| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.146 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.125892 |
| MT2A | metallothionein 2A | 0.107157 |
| TMSB10 | thymosin beta 10 | 0.100375 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0943999 |
| PTMA | prothymosin, alpha | 0.0925991 |
| LOC112694756 | uncharaterized LOC112694756 | 0.085488 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0807717 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.07768 |
| FMNL2 | formin-like 2 | 0.0746072 |
| PGK1 | phosphoglycerate kinase 1 | 0.0677002 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0673558 |
| NONO | non-POU domain containing, octamer-binding | 0.0666565 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0658114 |
| DST | dystonin | 0.0640747 |
| RPL3 | ribosomal protein L3 | 0.0588118 |
| YBX1 | Y box binding protein 1 | 0.0548343 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0523785 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0501145 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0499848 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0488127 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0481023 |
| RPL23 | ribosomal protein L23 | 0.0477762 |
| PLEC | plectin | 0.0473153 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0467163 |
| APP | amyloid beta (A4) precursor protein | 0.0461707 |
| EZR | ezrin | 0.04579 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0457496 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0455462 |
| XPO1 | exportin 1 | 0.0452015 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0443616 |
| ZNF292 | zinc finger protein 292 | 0.0439674 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0438747 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0436923 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0424878 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.041026 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0406338 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0405904 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0405846 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0403634 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0401413 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0388194 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0387797 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0385367 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0382262 |
| OGA | O-GlcNAcase | 0.0381974 |
| SEPTIN2 | septin 2 | 0.0381777 |
| MT1X | metallothionein 1X | 0.0380533 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0379866 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0378309 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.037515 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0366207 |
| NIBAN2 | niban apoptosis regulator 2 | 0.036135 |
| FUS | FUS RNA binding protein | 0.035898 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0356132 |
| SRPK2 | SRSF protein kinase 2 | 0.0355171 |
| RPL35A | ribosomal protein L35a | 0.0349457 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0349425 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0349368 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0343967 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0343326 |
| SPAG9 | sperm associated antigen 9 | 0.0342107 |
| PODXL | podocalyxin-like | 0.0341439 |
| PCBP2 | poly(rC) binding protein 2 | 0.0340017 |
| NDRG1 | N-myc downstream regulated 1 | 0.0338185 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0338181 |
| SET | SET nuclear proto-oncogene | 0.0338071 |
| RLIM | ring finger protein, LIM domain interacting | 0.0337508 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0326688 |
| PKM | pyruvate kinase, muscle | 0.0325055 |
| RPS19 | ribosomal protein S19 | 0.0323381 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0323153 |
| FLNB | filamin B, beta | 0.0322764 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0318808 |
| CEP250 | centrosomal protein 250kDa | 0.0316075 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0311579 |
| NUP58 | nucleoporin 58 | 0.0307786 |
| MSN | moesin | 0.0307507 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0307063 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0306556 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0306033 |
| ADAR | adenosine deaminase, RNA-specific | 0.0301889 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0299148 |
| RPL37 | ribosomal protein L37 | 0.0297248 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0295539 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0294687 |
| WDR45B | WD repeat domain 45B | 0.0294596 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0288056 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0287132 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0286703 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0285951 |
| PDE8A | phosphodiesterase 8A | 0.0285859 |
| YBX3 | Y box binding protein 3 | 0.028561 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0284561 |
| FOSL1 | FOS-like antigen 1 | 0.0283773 |
| LDHA | lactate dehydrogenase A | 0.0282582 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0281103 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0279575 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0277475 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0271935 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.339386 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.129002 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.119002 |
| TP63 | tumor protein p63 | -0.0938546 |
| TXNRD1 | thioredoxin reductase 1 | -0.0917305 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0650984 |
| CD44 | CD44 molecule (Indian blood group) | -0.0606017 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0538185 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0529954 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0466731 |
| EHBP1 | EH domain binding protein 1 | -0.0450886 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0450428 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0442231 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.038893 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0382457 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.036449 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0350551 |
| HMGA1 | high mobility group AT-hook 1 | -0.0341393 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.032221 |
| EGR1 | early growth response 1 | -0.0317764 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0310602 |
| VIM | vimentin | -0.0308055 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0299011 |
| BPTF | bromodomain PHD finger transcription factor | -0.0291486 |
| USP34 | ubiquitin specific peptidase 34 | -0.0275411 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0273484 |
| PDE10A | phosphodiesterase 10A | -0.026779 |
| SRGN | serglycin | -0.0264646 |
| RPS2 | ribosomal protein S2 | -0.0255544 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.024747 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0244786 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0243356 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0240225 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0235267 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0233448 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0222647 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0220343 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0219095 |
| OSMR | oncostatin M receptor | -0.0213327 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.021075 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0210099 |
| PLSCR1 | phospholipid scramblase 1 | -0.0210027 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0209441 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0197042 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.019647 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.019414 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.019072 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0182085 |
| CANX | calnexin | -0.0182035 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0181685 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0181615 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0179626 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0177741 |
| CDK13 | cyclin-dependent kinase 13 | -0.0177548 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0176806 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0175939 |
| EREG | epiregulin | -0.0173936 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0172995 |
| RIGI | RNA sensor RIG-I | -0.0172077 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0171597 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0169342 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0164945 |
| CDCP1 | CUB domain containing protein 1 | -0.0163809 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0162448 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0162269 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0161327 |
| MYO9A | myosin IXA | -0.0160478 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0157023 |
| GNAS | GNAS complex locus | -0.0154768 |
| AHI1 | Abelson helper integration site 1 | -0.0152981 |
| NEK10 | NIMA-related kinase 10 | -0.0151899 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0151832 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0150861 |
| GOLGB1 | golgin B1 | -0.014764 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.014756 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0146644 |
| PHF14 | PHD finger protein 14 | -0.0142956 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0139146 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0138924 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0137957 |
| NBEAL1 | neurobeachin-like 1 | -0.0133842 |
| INTS6 | integrator complex subunit 6 | -0.0133417 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0133199 |
| CEP112 | centrosomal protein 112kDa | -0.0133189 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0131996 |
| CADM2 | cell adhesion molecule 2 | -0.0131913 |
| MAP4 | microtubule-associated protein 4 | -0.0130437 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0130319 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.012736 |
| RGS4 | regulator of G-protein signaling 4 | -0.0126881 |
| HDAC8 | histone deacetylase 8 | -0.0126295 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0126266 |
| GAN | gigaxonin | -0.0126116 |
| BMERB1 | bMERB domain containing 1 | -0.0126008 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0123967 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0123104 |
| ATF6 | activating transcription factor 6 | -0.0122185 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0122073 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0119668 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0119098 |
