| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.115684 |
| ACTG1 | actin gamma 1 | 0.110226 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0966532 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0951615 |
| TMSB10 | thymosin beta 10 | 0.0910983 |
| RPL3 | ribosomal protein L3 | 0.0869397 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0775872 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0769264 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0677913 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0659829 |
| CMIP | c-Maf inducing protein | 0.0649317 |
| ACTN1 | actinin, alpha 1 | 0.0602173 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0520516 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0506941 |
| HLA-B | major histocompatibility complex, class I, B | 0.0492087 |
| YBX3 | Y box binding protein 3 | 0.0490656 |
| GRAMD1B | GRAM domain containing 1B | 0.0487348 |
| PLEC | plectin | 0.0484847 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0470793 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0451664 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0451302 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0437612 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0432791 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0432149 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.042041 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0414365 |
| MSN | moesin | 0.0407172 |
| FLNA | filamin A, alpha | 0.0387515 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0367193 |
| APP | amyloid beta (A4) precursor protein | 0.0355804 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.034289 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0337497 |
| NONO | non-POU domain containing, octamer-binding | 0.0337187 |
| SFTPA2 | surfactant protein A2 | 0.0334959 |
| HDGF | hepatoma-derived growth factor | 0.0319767 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0314652 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0313069 |
| SMAD3 | SMAD family member 3 | 0.0312734 |
| LDHA | lactate dehydrogenase A | 0.0307809 |
| FUS | FUS RNA binding protein | 0.0307186 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0296706 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0295256 |
| RPL41 | ribosomal protein L41 | 0.0293052 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0293016 |
| SPAG5 | sperm associated antigen 5 | 0.0292965 |
| HLA-C | major histocompatibility complex, class I, C | 0.0292632 |
| ADAR | adenosine deaminase, RNA-specific | 0.0290366 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0290083 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0289944 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0289679 |
| USP36 | ubiquitin specific peptidase 36 | 0.0288261 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0288086 |
| FAM107B | family with sequence similarity 107, member B | 0.0287403 |
| MEF2D | myocyte enhancer factor 2D | 0.0279786 |
| NDRG1 | N-myc downstream regulated 1 | 0.0279133 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0277652 |
| ERGIC3 | ERGIC and golgi 3 | 0.0277278 |
| PFKP | phosphofructokinase, platelet | 0.0275907 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0275415 |
| EGR1 | early growth response 1 | 0.0273785 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0272957 |
| BRD2 | bromodomain containing 2 | 0.0266927 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0266858 |
| TPI1 | triosephosphate isomerase 1 | 0.0263012 |
| FLNB | filamin B, beta | 0.0262952 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0262054 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.026187 |
| RPL11 | ribosomal protein L11 | 0.0261042 |
| TPM3 | tropomyosin 3 | 0.0260338 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0260148 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.026014 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0257039 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0250586 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0250076 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0248854 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0248032 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 | 0.0246378 |
| RRM2 | ribonucleotide reductase M2 | 0.0244711 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0244228 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0243593 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0243079 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0242252 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0241183 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0237381 |
| CABIN1 | calcineurin binding protein 1 | 0.0237211 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0235447 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0234666 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0232941 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0232784 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0232349 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0231258 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0225847 |
| DIDO1 | death inducer-obliterator 1 | 0.0225822 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.022524 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0222947 |
| RPL35A | ribosomal protein L35a | 0.022212 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0221228 |
| USP32 | ubiquitin specific peptidase 32 | 0.0219793 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0218588 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0215463 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.302937 |
| FTL | ferritin, light polypeptide | -0.202783 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.150225 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.12753 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109049 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0967878 |
| FGB | fibrinogen beta chain | -0.0899385 |
| TXNRD1 | thioredoxin reductase 1 | -0.0855346 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0744113 |
| RPLP1 | ribosomal protein, large, P1 | -0.0553536 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0552493 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0474956 |
| IER3 | immediate early response 3 | -0.046867 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0466586 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0456307 |
| BICC1 | BicC family RNA binding protein 1 | -0.0414789 |
| RPS12 | ribosomal protein S12 | -0.0397541 |
| RPS2 | ribosomal protein S2 | -0.0390796 |
| EFNA5 | ephrin-A5 | -0.0365965 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0360862 |
| SVIL | supervillin | -0.0360793 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0356481 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0352534 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0349801 |
| RPS5 | ribosomal protein S5 | -0.0344605 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0339224 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0334801 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.033374 |
| HDAC9 | histone deacetylase 9 | -0.0330468 |
| RPL19 | ribosomal protein L19 | -0.0330146 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0322648 |
| SLC38A1 | solute carrier family 38, member 1 | -0.03149 |
| FGG | fibrinogen gamma chain | -0.0297765 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0295674 |
| SRGN | serglycin | -0.0293084 |
| IGF2 | insulin-like growth factor 2 | -0.0291172 |
| PTMA | prothymosin, alpha | -0.0287863 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0286226 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0285987 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0283147 |
| AHR | aryl hydrocarbon receptor | -0.0282871 |
| FNBP1L | formin binding protein 1-like | -0.0282114 |
| NTN4 | netrin 4 | -0.0277186 |
| ERBIN | erbb2 interacting protein | -0.0275437 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0270773 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0270468 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0266536 |
| S100A10 | S100 calcium binding protein A10 | -0.0265196 |
| RPS25 | ribosomal protein S25 | -0.025991 |
| RPS8 | ribosomal protein S8 | -0.0259241 |
| CANX | calnexin | -0.0257808 |
| GNAS | GNAS complex locus | -0.0257034 |
| RPL8 | ribosomal protein L8 | -0.02543 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0253179 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0251552 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0250983 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0250035 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0249993 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0245905 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0245902 |
| NOP58 | NOP58 ribonucleoprotein | -0.0245507 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0244248 |
| RTN4 | reticulon 4 | -0.0239805 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0238453 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0232352 |
| ZNF207 | zinc finger protein 207 | -0.0230749 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0230177 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0229023 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0228187 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0227949 |
| RNF145 | ring finger protein 145 | -0.0226931 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0226553 |
| NEGR1 | neuronal growth regulator 1 | -0.0225417 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0225139 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0218048 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0215513 |
| KLF6 | Kruppel-like factor 6 | -0.0213566 |
| RPS20 | ribosomal protein S20 | -0.0211672 |
| RHOA | ras homolog family member A | -0.0210041 |
| WBP11 | WW domain binding protein 11 | -0.0208091 |
| RPL14 | ribosomal protein L14 | -0.0207314 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0206066 |
| CLDN1 | claudin 1 | -0.0205758 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0204016 |
| AFTPH | aftiphilin | -0.0203792 |
| MAP4 | microtubule-associated protein 4 | -0.0202965 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0202221 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0201988 |
| RPL23A | ribosomal protein L23a | -0.019897 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0194708 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0192312 |
| KIF5B | kinesin family member 5B | -0.0192262 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0189534 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0186035 |
| RDX | radixin | -0.0185891 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0185644 |
| RBM25 | RNA binding motif protein 25 | -0.0181836 |
| HMGB1 | high mobility group box 1 | -0.0181499 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0180065 |
| CUX1 | cut-like homeobox 1 | -0.0175618 |
