| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.154427 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0802166 |
| FAM13A | family with sequence similarity 13, member A | 0.0801326 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0775052 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0749444 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0749218 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0728844 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0724459 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0724044 |
| DST | dystonin | 0.0700584 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0699824 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0697222 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0694805 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0684253 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.062329 |
| STC1 | stanniocalcin 1 | 0.0610761 |
| PCBP2 | poly(rC) binding protein 2 | 0.0601033 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0559283 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0554699 |
| EFNA5 | ephrin-A5 | 0.0544734 |
| PGK1 | phosphoglycerate kinase 1 | 0.0530918 |
| NUP58 | nucleoporin 58 | 0.0525705 |
| MMP1 | matrix metallopeptidase 1 | 0.0524185 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0520822 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.051941 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0513239 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0505148 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0502727 |
| EGFR | epidermal growth factor receptor | 0.0502096 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0495726 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0495353 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0493258 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0486945 |
| SEPTIN9 | septin 9 | 0.0483817 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.047152 |
| ZNF292 | zinc finger protein 292 | 0.0471163 |
| CDH13 | cadherin 13 | 0.0470977 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0470404 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0461417 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0459823 |
| PTMA | prothymosin, alpha | 0.0457505 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0456483 |
| RPL3 | ribosomal protein L3 | 0.0449937 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0449468 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0446727 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0438096 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0436074 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0435832 |
| NPTN | neuroplastin | 0.0435415 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.043405 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0426582 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.042172 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.040933 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0405618 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0404819 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0404732 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0403393 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.039206 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0391942 |
| XPO1 | exportin 1 | 0.0389623 |
| TMSB4X | thymosin beta 4, X-linked | 0.038762 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0381883 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0378259 |
| LAMA4 | laminin, alpha 4 | 0.0375514 |
| ANGPTL4 | angiopoietin-like 4 | 0.0374738 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0373534 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0371104 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0368335 |
| VEGFA | vascular endothelial growth factor A | 0.036807 |
| MXD1 | MAX dimerization protein 1 | 0.0368068 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0366282 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0364707 |
| SON | SON DNA binding protein | 0.0362712 |
| GOLGA4 | golgin A4 | 0.0362053 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.035968 |
| NBAS | neuroblastoma amplified sequence | 0.0358368 |
| PLEC | plectin | 0.0355746 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0353789 |
| AFDN | afadin, adherens junction formation factor | 0.0352877 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0352129 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0351063 |
| UBAP2L | ubiquitin associated protein 2-like | 0.035072 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0350572 |
| FLNB | filamin B, beta | 0.0347596 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0345819 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0345716 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0345157 |
| KRT8 | keratin 8, type II | 0.0343943 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.033958 |
| INSIG2 | insulin induced gene 2 | 0.0338567 |
| DTNA | dystrobrevin, alpha | 0.0335287 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0332678 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0331661 |
| SMAD3 | SMAD family member 3 | 0.033109 |
| YTHDC1 | YTH domain containing 1 | 0.0330326 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0321343 |
| NRG1 | neuregulin 1 | 0.0319612 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.031522 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0314007 |
| TPM3 | tropomyosin 3 | 0.0312506 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.265815 |
| MYO1E | myosin IE | -0.132771 |
| FTL | ferritin, light polypeptide | -0.10851 |
| ANXA2 | annexin A2 | -0.0997887 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0872207 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0866125 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0845182 |
| ANXA1 | annexin A1 | -0.0793499 |
| S100A9 | S100 calcium binding protein A9 | -0.0774386 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0762822 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0718403 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0714238 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0680156 |
| S100A10 | S100 calcium binding protein A10 | -0.0659587 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0654266 |
| VIM | vimentin | -0.064468 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0625792 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0578975 |
| KRT17 | keratin 17, type I | -0.0575665 |
| ATOSA | atos homolog A | -0.05613 |
| LMO7 | LIM domain 7 | -0.0556155 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0554875 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0525868 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0524457 |
| KYNU | kynureninase | -0.0502745 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0500898 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0499243 |
| SLMAP | sarcolemma associated protein | -0.0491318 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0486373 |
| TMEM123 | transmembrane protein 123 | -0.0485048 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.047905 |
| ERBIN | erbb2 interacting protein | -0.0478041 |
| PRRC2C | proline-rich coiled-coil 2C | -0.047687 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0476633 |
| TXNIP | thioredoxin interacting protein | -0.0472825 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0470542 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0446072 |
| UBAP1 | ubiquitin associated protein 1 | -0.0437864 |
| SRPK2 | SRSF protein kinase 2 | -0.0435045 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0432804 |
| PERP | PERP, TP53 apoptosis effector | -0.0432708 |
| ZNF609 | zinc finger protein 609 | -0.0429174 |
| INTS6 | integrator complex subunit 6 | -0.0425458 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0422608 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0421942 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0419815 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0411443 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0404746 |
| RPS11 | ribosomal protein S11 | -0.0401105 |
| PARD3 | par-3 family cell polarity regulator | -0.0400917 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0398117 |
| CYTH1 | cytohesin 1 | -0.0397991 |
| CCNI | cyclin I | -0.0397476 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0396083 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0392387 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0387649 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0387089 |
| CCDC6 | coiled-coil domain containing 6 | -0.0385597 |
| GDF15 | growth differentiation factor 15 | -0.038403 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0382526 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0380844 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0377984 |
| RPS29 | ribosomal protein S29 | -0.0368768 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0367427 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0365431 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.03624 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0360359 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0360296 |
| RPS4X | ribosomal protein S4, X-linked | -0.0356701 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0356508 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0356417 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0356116 |
| PKM | pyruvate kinase, muscle | -0.0353974 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0353277 |
| ZNF217 | zinc finger protein 217 | -0.0348288 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0344759 |
| FRYL | FRY-like | -0.0343603 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0341128 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0340039 |
| GPC6 | glypican 6 | -0.0339155 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0334474 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0334234 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0333095 |
| LAMB1 | laminin, beta 1 | -0.0332033 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0328988 |
| PHF21A | PHD finger protein 21A | -0.0327779 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0326013 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0315249 |
| TAOK3 | TAO kinase 3 | -0.031459 |
| YAP1 | Yes-associated protein 1 | -0.0313351 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0313248 |
| MYO6 | myosin VI | -0.0310506 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0306322 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0305956 |
| EMP1 | epithelial membrane protein 1 | -0.0304699 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0303878 |
| CD44 | CD44 molecule (Indian blood group) | -0.0303391 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0302706 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.0302684 |
| SRP54 | signal recognition particle 54kDa | -0.0302296 |
