| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0828622 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.075792 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0744135 |
| TXNRD1 | thioredoxin reductase 1 | 0.0704056 |
| OGA | O-GlcNAcase | 0.0696498 |
| KRT18 | keratin 18, type I | 0.063429 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0586743 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0573635 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0515897 |
| YBX3 | Y box binding protein 3 | 0.0509276 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.049147 |
| PLEC | plectin | 0.0490223 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0488172 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0484964 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0482266 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0479779 |
| ADAR | adenosine deaminase, RNA-specific | 0.0476982 |
| NONO | non-POU domain containing, octamer-binding | 0.0465416 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0452867 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0436483 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0429878 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0423051 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0420657 |
| PGK1 | phosphoglycerate kinase 1 | 0.0417047 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0409123 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0407934 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0398622 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0397479 |
| CTTN | cortactin | 0.0380763 |
| GRAMD1B | GRAM domain containing 1B | 0.0377921 |
| RPL3 | ribosomal protein L3 | 0.0371168 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0365961 |
| YBX1 | Y box binding protein 1 | 0.0358051 |
| TPM3 | tropomyosin 3 | 0.0356194 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0355134 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0354933 |
| RBM39 | RNA binding motif protein 39 | 0.0346036 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0345713 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.033896 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0323592 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.032206 |
| PER1 | period circadian clock 1 | 0.0318822 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0317497 |
| XPO1 | exportin 1 | 0.0316006 |
| RLIM | ring finger protein, LIM domain interacting | 0.0315485 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0314197 |
| FUS | FUS RNA binding protein | 0.0313324 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0312256 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0305465 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0303795 |
| RTN4 | reticulon 4 | 0.0298277 |
| CEP192 | centrosomal protein 192kDa | 0.029805 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0296828 |
| RRM2 | ribonucleotide reductase M2 | 0.0295314 |
| KRT8 | keratin 8, type II | 0.0294425 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0293896 |
| PHIP | pleckstrin homology domain interacting protein | 0.0293358 |
| H1-0 | H1.0 linker histone | 0.0292543 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0289046 |
| DIDO1 | death inducer-obliterator 1 | 0.0281759 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0278453 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0276828 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0275642 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0272827 |
| RPL4 | ribosomal protein L4 | 0.0270945 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.026845 |
| USP22 | ubiquitin specific peptidase 22 | 0.0265281 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0264848 |
| CEP250 | centrosomal protein 250kDa | 0.0263063 |
| MKI67 | marker of proliferation Ki-67 | 0.0262722 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0262664 |
| DENR | density-regulated protein | 0.026199 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0258446 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0254646 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.025229 |
| APP | amyloid beta (A4) precursor protein | 0.025159 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.024806 |
| SEPTIN2 | septin 2 | 0.0246397 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0245575 |
| SET | SET nuclear proto-oncogene | 0.0245005 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0241234 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0240344 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0239641 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0236021 |
| MORF4L2 | mortality factor 4 like 2 | 0.0233836 |
| MATR3 | matrin 3 | 0.0233608 |
| RBM33 | RNA binding motif protein 33 | 0.0232405 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0231471 |
| UBC | ubiquitin C | 0.0229564 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.022844 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0227731 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0227516 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0225796 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0224563 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0224414 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0224384 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0222999 |
| ANXA5 | annexin A5 | 0.0222433 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0222158 |
| RPL37 | ribosomal protein L37 | 0.0218962 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.125829 |
| RAD51B | RAD51 paralog B | -0.0728561 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0685163 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0643635 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0631437 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0598089 |
| EGFR | epidermal growth factor receptor | -0.0539189 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0523169 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0521627 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0503296 |
| EGR1 | early growth response 1 | -0.0494683 |
| HMGA2 | high mobility group AT-hook 2 | -0.0474997 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0468302 |
| POTEF | POTE ankyrin domain family, member F | -0.0447957 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0406371 |
| BPTF | bromodomain PHD finger transcription factor | -0.0377547 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0374885 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0370226 |
| ATXN1 | ataxin 1 | -0.0354871 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0348578 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0345177 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0342525 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0332716 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0329693 |
| USP34 | ubiquitin specific peptidase 34 | -0.0328892 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0328299 |
| AEBP2 | AE binding protein 2 | -0.0325521 |
| NF1 | neurofibromin 1 | -0.0322541 |
| PDE10A | phosphodiesterase 10A | -0.0312084 |
| INTS6 | integrator complex subunit 6 | -0.0312033 |
| NABP1 | nucleic acid binding protein 1 | -0.030528 |
| MAP4 | microtubule-associated protein 4 | -0.0285904 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0279609 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.027817 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0276216 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.02759 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0273265 |
| MCL1 | myeloid cell leukemia 1 | -0.0272838 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0272696 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0269551 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0263012 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.025909 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0257467 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0254579 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0252476 |
| WDR70 | WD repeat domain 70 | -0.0249435 |
| NBEAL1 | neurobeachin-like 1 | -0.024775 |
| ZNF638 | zinc finger protein 638 | -0.0246437 |
| GOLGB1 | golgin B1 | -0.0245963 |
| EXOC4 | exocyst complex component 4 | -0.0245742 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0243467 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0242083 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0241764 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0240563 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0235417 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.023334 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.023324 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0228866 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0223773 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0219269 |
| RYR3 | ryanodine receptor 3 | -0.0218021 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0217444 |
| FTL | ferritin, light polypeptide | -0.0215577 |
| CCNL1 | cyclin L1 | -0.0215373 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0206381 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0205109 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0204838 |
| PTK2 | protein tyrosine kinase 2 | -0.020433 |
| DIAPH2 | diaphanous-related formin 2 | -0.0203897 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0201538 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0197613 |
| PHF14 | PHD finger protein 14 | -0.0195461 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0195381 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0194146 |
| CUX1 | cut-like homeobox 1 | -0.0193375 |
| EHBP1 | EH domain binding protein 1 | -0.019156 |
| HMGA1 | high mobility group AT-hook 1 | -0.0190606 |
| TAPBP | TAP binding protein (tapasin) | -0.0188957 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0188797 |
| GPATCH2L | G patch domain containing 2-like | -0.0187268 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0186824 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0185305 |
| THADA | thyroid adenoma associated | -0.0184162 |
| TPM2 | tropomyosin 2 (beta) | -0.0184059 |
| GPHN | gephyrin | -0.0183341 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.018264 |
| HDAC8 | histone deacetylase 8 | -0.0182236 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0182202 |
| SVIL | supervillin | -0.018131 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0180559 |
| ATM | ATM serine/threonine kinase | -0.0179786 |
| OSMR | oncostatin M receptor | -0.0178682 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0177709 |
| DST | dystonin | -0.0177665 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0176648 |
| NLGN1 | neuroligin 1 | -0.0175041 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0173797 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.0173679 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0173619 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0173139 |
