| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.170133 |
| PLEC | plectin | 0.162004 |
| NDRG1 | N-myc downstream regulated 1 | 0.128622 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.113623 |
| VEGFA | vascular endothelial growth factor A | 0.0918633 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0818756 |
| LAMB3 | laminin, beta 3 | 0.0802519 |
| TMSB4X | thymosin beta 4, X-linked | 0.0801067 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0795251 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0779787 |
| LAMC2 | laminin, gamma 2 | 0.0768709 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0718085 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0714974 |
| CALR | calreticulin | 0.0702142 |
| ACTG1 | actin gamma 1 | 0.0685558 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0677479 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0677381 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0641623 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0618679 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0613691 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0609088 |
| KRT8 | keratin 8, type II | 0.0574448 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0550985 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0547499 |
| RPL3 | ribosomal protein L3 | 0.0526257 |
| FLNA | filamin A, alpha | 0.0520845 |
| KRT7 | keratin 7, type II | 0.0505607 |
| RPL4 | ribosomal protein L4 | 0.0496873 |
| HLA-B | major histocompatibility complex, class I, B | 0.0490704 |
| RACK1 | receptor for activated C kinase 1 | 0.0469592 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0457399 |
| SMAD3 | SMAD family member 3 | 0.045254 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0450494 |
| TPM3 | tropomyosin 3 | 0.0447239 |
| MSN | moesin | 0.0446918 |
| RPL37 | ribosomal protein L37 | 0.044439 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0442814 |
| FLNB | filamin B, beta | 0.0432447 |
| SQSTM1 | sequestosome 1 | 0.0416893 |
| SDC4 | syndecan 4 | 0.0416076 |
| NONO | non-POU domain containing, octamer-binding | 0.0414736 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0410774 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0408347 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0407333 |
| PLAU | plasminogen activator, urokinase | 0.0404057 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0397181 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0392781 |
| KRT18 | keratin 18, type I | 0.0391252 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0386163 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0374596 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0371872 |
| RPL23 | ribosomal protein L23 | 0.0364251 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0361219 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0353996 |
| MYO5B | myosin VB | 0.035384 |
| EZR | ezrin | 0.0350708 |
| PKM | pyruvate kinase, muscle | 0.0344027 |
| LMNA | lamin A/C | 0.034385 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0326405 |
| TUFT1 | tuftelin 1 | 0.0324009 |
| HLA-A | major histocompatibility complex, class I, A | 0.0319954 |
| ASPH | aspartate beta-hydroxylase | 0.0319831 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0316531 |
| SET | SET nuclear proto-oncogene | 0.0316381 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0315736 |
| RPS3 | ribosomal protein S3 | 0.0313686 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.031033 |
| APP | amyloid beta (A4) precursor protein | 0.0308709 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0284397 |
| DUSP10 | dual specificity phosphatase 10 | 0.0282782 |
| PCBP2 | poly(rC) binding protein 2 | 0.0279582 |
| RPL11 | ribosomal protein L11 | 0.0279353 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0277582 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0277331 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.027705 |
| RPS12 | ribosomal protein S12 | 0.0273931 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0271228 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0269765 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0269594 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0268415 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0265069 |
| HDGF | hepatoma-derived growth factor | 0.0261537 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0258389 |
| RPL37A | ribosomal protein L37a | 0.0256676 |
| BRD2 | bromodomain containing 2 | 0.0255344 |
| TSPAN15 | tetraspanin 15 | 0.0253931 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0250825 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0247617 |
| RPL13A | ribosomal protein L13a | 0.0246553 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0245418 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0242003 |
| ANXA11 | annexin A11 | 0.0238688 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0238183 |
| IRF6 | interferon regulatory factor 6 | 0.023817 |
| PTK2 | protein tyrosine kinase 2 | 0.0237406 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0236449 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0235661 |
| YBX3 | Y box binding protein 3 | 0.0235392 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0233431 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0232001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.312505 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.133853 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.133049 |
| FTL | ferritin, light polypeptide | -0.0741738 |
| POTEF | POTE ankyrin domain family, member F | -0.0634363 |
| CD2AP | CD2-associated protein | -0.0605291 |
| HMGA1 | high mobility group AT-hook 1 | -0.0582418 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.058125 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0537125 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.053142 |
| TMEM263 | transmembrane protein 263 | -0.0502795 |
| S100A10 | S100 calcium binding protein A10 | -0.0456353 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.043282 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0409131 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0406273 |
| TMEM123 | transmembrane protein 123 | -0.0397717 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0394607 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0387515 |
| UBC | ubiquitin C | -0.0378794 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0371026 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0363652 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0362914 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0356575 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0356539 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0355724 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0355638 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0344005 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.032998 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0329475 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0324458 |
| ERBIN | erbb2 interacting protein | -0.0324218 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0320937 |
| CCNI | cyclin I | -0.0314543 |
| LMO7 | LIM domain 7 | -0.0308139 |
| MAP4 | microtubule-associated protein 4 | -0.0303937 |
| CANX | calnexin | -0.0302187 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0301184 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0293646 |
| GNAS | GNAS complex locus | -0.0284611 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0282255 |
| TOP1 | topoisomerase (DNA) I | -0.0281387 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0280455 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0265321 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0261084 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0256893 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0255833 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0251612 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0248781 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0242701 |
| JMJD1C | jumonji domain containing 1C | -0.0238019 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0236356 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0232052 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0231304 |
| WASF2 | WAS protein family, member 2 | -0.0231267 |
| RPS23 | ribosomal protein S23 | -0.023095 |
| CCND1 | cyclin D1 | -0.0229919 |
| RAB1A | RAB1A, member RAS oncogene family | -0.022901 |
| SLMAP | sarcolemma associated protein | -0.0227836 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0226916 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0226688 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0225927 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0218306 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0217823 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0216032 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0215168 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0210237 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0206622 |
| SETD5 | SET domain containing 5 | -0.0204282 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0201211 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0200542 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0198718 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0195534 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0194677 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0193572 |
| PTMA | prothymosin, alpha | -0.019309 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0189632 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0188978 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0187855 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0187453 |
| SP100 | SP100 nuclear antigen | -0.0187246 |
| NRP1 | neuropilin 1 | -0.0186654 |
| RNF145 | ring finger protein 145 | -0.0186373 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0185833 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0185219 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0184347 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0184148 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0183902 |
| PARD3 | par-3 family cell polarity regulator | -0.0183188 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0181477 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0178531 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0176765 |
| RPL8 | ribosomal protein L8 | -0.0176524 |
| IER3 | immediate early response 3 | -0.0176309 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0174697 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0173863 |
| RPL32 | ribosomal protein L32 | -0.0172469 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0172085 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.017194 |
| TRAM1 | translocation associated membrane protein 1 | -0.0171852 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0171682 |
