| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.133269 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0971602 |
| TMSB10 | thymosin beta 10 | 0.0885423 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0884655 |
| RPL3 | ribosomal protein L3 | 0.0874644 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0855973 |
| NONO | non-POU domain containing, octamer-binding | 0.0825613 |
| DST | dystonin | 0.0811586 |
| EFNA5 | ephrin-A5 | 0.0767413 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0761303 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.074947 |
| LOC112694756 | uncharaterized LOC112694756 | 0.063657 |
| MCL1 | myeloid cell leukemia 1 | 0.0628135 |
| TBXT | T-box transcription factor T | 0.0591154 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0586767 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0564443 |
| MSN | moesin | 0.0547614 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0535592 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0516094 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0513369 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0485623 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0473207 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0470118 |
| B2M | beta-2-microglobulin | 0.0459651 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0456619 |
| GRAMD1B | GRAM domain containing 1B | 0.0452572 |
| FLNB | filamin B, beta | 0.0448245 |
| HDAC4 | histone deacetylase 4 | 0.0446336 |
| PGK1 | phosphoglycerate kinase 1 | 0.0439089 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0425401 |
| RLIM | ring finger protein, LIM domain interacting | 0.0413008 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0408732 |
| PCBP2 | poly(rC) binding protein 2 | 0.0407714 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0402848 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0397434 |
| YBX1 | Y box binding protein 1 | 0.0392878 |
| FLNA | filamin A, alpha | 0.0391588 |
| HLA-A | major histocompatibility complex, class I, A | 0.0390902 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0387582 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0383711 |
| YBX3 | Y box binding protein 3 | 0.037263 |
| RPL23 | ribosomal protein L23 | 0.0372071 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0368285 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.036167 |
| CDH13 | cadherin 13 | 0.0360478 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0355856 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0355041 |
| PRELID2 | PRELI domain containing 2 | 0.0351829 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0348581 |
| TMSB4X | thymosin beta 4, X-linked | 0.0347075 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0346933 |
| ANXA1 | annexin A1 | 0.034644 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0334465 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0334393 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0329639 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0324863 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0321673 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0320365 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0318277 |
| DENND1A | DENN/MADD domain containing 1A | 0.0309684 |
| RPL11 | ribosomal protein L11 | 0.0307891 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0306843 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0303163 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0300726 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0300098 |
| HLA-B | major histocompatibility complex, class I, B | 0.0298903 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0293154 |
| RPL35A | ribosomal protein L35a | 0.0288803 |
| TPM3 | tropomyosin 3 | 0.028537 |
| AUTS2 | autism susceptibility candidate 2 | 0.0284674 |
| DNER | delta/notch-like EGF repeat containing | 0.0284044 |
| LDHA | lactate dehydrogenase A | 0.0281151 |
| MORF4L2 | mortality factor 4 like 2 | 0.0279996 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0274568 |
| ACTG1 | actin gamma 1 | 0.0274277 |
| RPL37 | ribosomal protein L37 | 0.0273941 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0273185 |
| RPL35 | ribosomal protein L35 | 0.027279 |
| SET | SET nuclear proto-oncogene | 0.0267998 |
| CTSL | cathepsin L | 0.0266995 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0261441 |
| HYOU1 | hypoxia up-regulated 1 | 0.0259705 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0256371 |
| ARGLU1 | arginine and glutamate rich 1 | 0.025517 |
| EZR | ezrin | 0.0254837 |
| PYGL | phosphorylase, glycogen, liver | 0.0253756 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0252646 |
| PKM | pyruvate kinase, muscle | 0.0251614 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.025139 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0248192 |
| GLRX | glutaredoxin (thioltransferase) | 0.0248125 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0244582 |
| RACK1 | receptor for activated C kinase 1 | 0.0244515 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0244498 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0244391 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0242913 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0240688 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.023811 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0237641 |
| CEP250 | centrosomal protein 250kDa | 0.0237546 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.166048 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.164612 |
| GDA | guanine deaminase | -0.151174 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.132595 |
| COL5A2 | collagen, type V, alpha 2 | -0.0909805 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0764262 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0742229 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0688766 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0682018 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0655822 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.063155 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0610431 |
| KYNU | kynureninase | -0.0588909 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.050593 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0493788 |
| SMYD3 | SET and MYND domain containing 3 | -0.0481691 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0471944 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0438024 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0429167 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0408046 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0402728 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0398503 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0392036 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0389023 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0383752 |
| TXNRD1 | thioredoxin reductase 1 | -0.0382909 |
| NTN4 | netrin 4 | -0.0382793 |
| SRGN | serglycin | -0.0375951 |
| NEK7 | NIMA-related kinase 7 | -0.0370172 |
| BMERB1 | bMERB domain containing 1 | -0.0367627 |
| OSMR | oncostatin M receptor | -0.0366023 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0364442 |
| TNPO1 | transportin 1 | -0.0341626 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.0337515 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0333677 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0326388 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0306755 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0300131 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0296699 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0290902 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0277107 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0272105 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0267993 |
| INHBA | inhibin, beta A | -0.0266022 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0262954 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.02629 |
| CD109 | CD109 molecule | -0.0253095 |
| JMJD1C | jumonji domain containing 1C | -0.0252549 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0249575 |
| RPS23 | ribosomal protein S23 | -0.0231837 |
| IER3 | immediate early response 3 | -0.0231685 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0227563 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.022419 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0221284 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.021888 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0217962 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0217917 |
| ENAH | enabled homolog (Drosophila) | -0.0216284 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0211186 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0207989 |
| FN1 | fibronectin 1 | -0.0202769 |
| VIM | vimentin | -0.020091 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0198782 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0197405 |
| TUSC3 | tumor suppressor candidate 3 | -0.0192011 |
| RPS2 | ribosomal protein S2 | -0.0189153 |
| NF1 | neurofibromin 1 | -0.0187581 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0186873 |
| PALLD | palladin, cytoskeletal associated protein | -0.0183094 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0180938 |
| PDE10A | phosphodiesterase 10A | -0.0180185 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0179397 |
| CCDC68 | coiled-coil domain containing 68 | -0.017862 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0177871 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0176396 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0175141 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0175086 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0172192 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0171004 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0169544 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0167787 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0167467 |
| PRKD3 | protein kinase D3 | -0.0167398 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0166961 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0165342 |
| CD44 | CD44 molecule (Indian blood group) | -0.0165125 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0163404 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0163198 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0162664 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0162629 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0162332 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0161324 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0161091 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0160975 |
| GNAS | GNAS complex locus | -0.0159276 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0153792 |
| GPHN | gephyrin | -0.0151624 |
| UBXN4 | UBX domain protein 4 | -0.0150613 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0150216 |
| BPTF | bromodomain PHD finger transcription factor | -0.0150119 |
