| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.135044 |
| PLEC | plectin | 0.110082 |
| RAD51B | RAD51 paralog B | 0.0954965 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0951269 |
| FMN1 | formin 1 | 0.0918789 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0876265 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0825843 |
| SEPTIN9 | septin 9 | 0.0794203 |
| PRELID2 | PRELI domain containing 2 | 0.0791814 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0790815 |
| FNIP1 | folliculin interacting protein 1 | 0.0775064 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0770724 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0762545 |
| COPA | coatomer protein complex, subunit alpha | 0.0760323 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0751261 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0716407 |
| CDC73 | cell division cycle 73 | 0.0712366 |
| INSIG2 | insulin induced gene 2 | 0.0697509 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0694108 |
| NDRG1 | N-myc downstream regulated 1 | 0.0693318 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0672324 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0670159 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0667934 |
| DSTN | destrin (actin depolymerizing factor) | 0.0662172 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0648201 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0647943 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0646021 |
| YBX1 | Y box binding protein 1 | 0.0639924 |
| ANKRD11 | ankyrin repeat domain 11 | 0.062697 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0614881 |
| FAM13A | family with sequence similarity 13, member A | 0.0593872 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0580339 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0570035 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0564759 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0557912 |
| TJP1 | tight junction protein 1 | 0.0555346 |
| VGF | VGF nerve growth factor inducible | 0.054887 |
| ABI1 | abl-interactor 1 | 0.0538149 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0526455 |
| TPR | translocated promoter region, nuclear basket protein | 0.0526126 |
| RBM39 | RNA binding motif protein 39 | 0.0524655 |
| PGK1 | phosphoglycerate kinase 1 | 0.0516031 |
| NRG1 | neuregulin 1 | 0.0508354 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0507073 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0502897 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0497525 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0487075 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.048421 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0483348 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0480073 |
| TPM4 | tropomyosin 4 | 0.0479416 |
| SBF2 | SET binding factor 2 | 0.0470318 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0470277 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0459762 |
| TXNRD1 | thioredoxin reductase 1 | 0.0455203 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0449481 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0442435 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0420988 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0419038 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0417804 |
| KIZ | kizuna centrosomal protein | 0.0417525 |
| TOP1 | topoisomerase (DNA) I | 0.041349 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0413309 |
| COG5 | component of oligomeric golgi complex 5 | 0.0407717 |
| FBXO11 | F-box protein 11 | 0.0407529 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0406763 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0397981 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.039677 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0396736 |
| USP34 | ubiquitin specific peptidase 34 | 0.038819 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0386545 |
| CMIP | c-Maf inducing protein | 0.0385443 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0381965 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0377805 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0370912 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.036943 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0368345 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0365155 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0364616 |
| LAMA4 | laminin, alpha 4 | 0.0362973 |
| RPL23 | ribosomal protein L23 | 0.0361654 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0361417 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0360438 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0349866 |
| ETNK1 | ethanolamine kinase 1 | 0.0348552 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0342427 |
| SLTM | SAFB-like, transcription modulator | 0.0332698 |
| DOCK4 | dedicator of cytokinesis 4 | 0.032998 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.032705 |
| RPL37 | ribosomal protein L37 | 0.0325834 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0324112 |
| ZNF148 | zinc finger protein 148 | 0.0320892 |
| EFNA5 | ephrin-A5 | 0.0319188 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0315368 |
| FN1 | fibronectin 1 | 0.0313612 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.031265 |
| TMEM39A | transmembrane protein 39A | 0.0311115 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0306735 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0306631 |
| NCKAP1 | NCK-associated protein 1 | 0.0302418 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.241737 |
| VIM | vimentin | -0.18987 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.120015 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.109016 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.108076 |
| EXT1 | exostosin glycosyltransferase 1 | -0.102449 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.102306 |
| RPLP0 | ribosomal protein, large, P0 | -0.0982256 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0955673 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0955625 |
| PTMA | prothymosin, alpha | -0.0933893 |
| JMJD1C | jumonji domain containing 1C | -0.0851691 |
| RPLP1 | ribosomal protein, large, P1 | -0.084648 |
| NF1 | neurofibromin 1 | -0.0798745 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0767784 |
| RPS8 | ribosomal protein S8 | -0.0755351 |
| RPL35A | ribosomal protein L35a | -0.0748044 |
| RPS16 | ribosomal protein S16 | -0.0734404 |
| VCL | vinculin | -0.0715264 |
| RPL11 | ribosomal protein L11 | -0.0698593 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0686243 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0662025 |
| MYO1E | myosin IE | -0.0658274 |
| TMSB10 | thymosin beta 10 | -0.0642671 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0627459 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0625227 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.060559 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0602472 |
| RPL12 | ribosomal protein L12 | -0.0601504 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0598689 |
| MED13L | mediator complex subunit 13-like | -0.0593241 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0590227 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0584951 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0581826 |
| EGFR | epidermal growth factor receptor | -0.0575806 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0573939 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0560263 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0549109 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0534646 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0532496 |
| CDH13 | cadherin 13 | -0.0526498 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0523341 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0518492 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0517268 |
| PRKCA | protein kinase C, alpha | -0.0514565 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0502193 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0501645 |
| RPLP2 | ribosomal protein, large, P2 | -0.0497779 |
| RTN4 | reticulon 4 | -0.0491018 |
| ASPH | aspartate beta-hydroxylase | -0.048679 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0483613 |
| RIGI | RNA sensor RIG-I | -0.0477421 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0466823 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0462821 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0462016 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0458394 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0458296 |
| PARD3 | par-3 family cell polarity regulator | -0.0452317 |
| RPS23 | ribosomal protein S23 | -0.0445845 |
| RPS27A | ribosomal protein S27a | -0.0437974 |
| VMP1 | vacuole membrane protein 1 | -0.0436911 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0435732 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0435063 |
| ATXN1 | ataxin 1 | -0.0433569 |
| BPTF | bromodomain PHD finger transcription factor | -0.0427384 |
| GPC6 | glypican 6 | -0.0427065 |
| GNAS | GNAS complex locus | -0.0412971 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0410724 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0403305 |
| ANO6 | anoctamin 6 | -0.0401837 |
| HMGA2 | high mobility group AT-hook 2 | -0.0391858 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0387759 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0386911 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0385824 |
| MT2A | metallothionein 2A | -0.0378123 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0374036 |
| SNX9 | sorting nexin 9 | -0.0372058 |
| PUM2 | pumilio RNA-binding family member 2 | -0.037089 |
| RACK1 | receptor for activated C kinase 1 | -0.036947 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0366799 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.036497 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0356563 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0355858 |
| RPS13 | ribosomal protein S13 | -0.0353939 |
| RPS6 | ribosomal protein S6 | -0.0346569 |
| RBM25 | RNA binding motif protein 25 | -0.033467 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0331781 |
| PEG10 | paternally expressed 10 | -0.0329234 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0329175 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0328541 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0319929 |
| RORA | RAR-related orphan receptor A | -0.0314867 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0314174 |
| DTNA | dystrobrevin, alpha | -0.0313033 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0311425 |
| RPS24 | ribosomal protein S24 | -0.0309605 |
| NAV2 | neuron navigator 2 | -0.0305491 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0304268 |
| ZNF207 | zinc finger protein 207 | -0.0299336 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0288599 |
