| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.12897 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.120736 |
| NONO | non-POU domain containing, octamer-binding | 0.0887867 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0816262 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0789552 |
| RPL3 | ribosomal protein L3 | 0.0752664 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0727163 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0709628 |
| DST | dystonin | 0.0650805 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0645615 |
| SFTPA2 | surfactant protein A2 | 0.0621285 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0576163 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0569012 |
| NTM | neurotrimin | 0.0566192 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0535094 |
| CCN2 | cellular communication network factor 2 | 0.0525196 |
| LOC112694756 | uncharaterized LOC112694756 | 0.05218 |
| RPL37 | ribosomal protein L37 | 0.0519474 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0513319 |
| FUS | FUS RNA binding protein | 0.0495167 |
| RPL11 | ribosomal protein L11 | 0.0482613 |
| ACTG1 | actin gamma 1 | 0.0481055 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0446313 |
| RFPL4B | ret finger protein-like 4B | 0.0425416 |
| HDAC9 | histone deacetylase 9 | 0.0411106 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0404224 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0403228 |
| DLX2 | distal-less homeobox 2 | 0.0396366 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0395951 |
| H1-2 | H1.2 linker histone, cluster member | 0.0387416 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.0380923 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0375819 |
| CALR | calreticulin | 0.0375063 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0357259 |
| RPS16 | ribosomal protein S16 | 0.0355325 |
| COL1A2 | collagen, type I, alpha 2 | 0.0354623 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0352614 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0345005 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.034081 |
| PGK1 | phosphoglycerate kinase 1 | 0.0340697 |
| CAPRIN1 | cell cycle associated protein 1 | 0.033751 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0336028 |
| B2M | beta-2-microglobulin | 0.0332324 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0326436 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0321753 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0320881 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0315837 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0313069 |
| SMYD3 | SET and MYND domain containing 3 | 0.0312852 |
| CPNE1 | copine I | 0.0310181 |
| ITGAV | integrin, alpha V | 0.0305135 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0303568 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0303165 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0302004 |
| ANXA1 | annexin A1 | 0.0301772 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0300509 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0298168 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0295966 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0295903 |
| SCRN1 | secernin 1 | 0.0295755 |
| MB21D2 | Mab-21 domain containing 2 | 0.0295011 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.029112 |
| RLIM | ring finger protein, LIM domain interacting | 0.0288388 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0284773 |
| PHF21A | PHD finger protein 21A | 0.0284227 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.028417 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0283397 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0281906 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0280565 |
| NUP98 | nucleoporin 98kDa | 0.0279611 |
| GRB2 | growth factor receptor-bound protein 2 | 0.0279473 |
| TMSB10 | thymosin beta 10 | 0.0278792 |
| SF1 | splicing factor 1 | 0.0278717 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0274436 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0273573 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.0271017 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0269325 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0266508 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0265609 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0265281 |
| HMGN1 | high mobility group nucleosome binding domain 1 | 0.0262333 |
| RPL35A | ribosomal protein L35a | 0.0261943 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0260123 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0259361 |
| TENM3 | teneurin transmembrane protein 3 | 0.0256355 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0256007 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0253685 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0251621 |
| APP | amyloid beta (A4) precursor protein | 0.0250146 |
| TFRC | transferrin receptor | 0.0250105 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0249274 |
| BRD4 | bromodomain containing 4 | 0.0248136 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0241462 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.024022 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0240205 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0240027 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0238819 |
| MORF4L2 | mortality factor 4 like 2 | 0.0236529 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0236243 |
| FIGN | fidgetin | 0.0235951 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10256 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0983955 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0779179 |
| MED13L | mediator complex subunit 13-like | -0.0749359 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0746624 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0723668 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0685595 |
| GPC3 | glypican 3 | -0.0636763 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0611346 |
| VIM | vimentin | -0.0563206 |
| HMGB1 | high mobility group box 1 | -0.0498352 |
| RDX | radixin | -0.0488103 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0476132 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0475006 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0464267 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0459706 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0451985 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0449561 |
| RBM25 | RNA binding motif protein 25 | -0.0431632 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0424404 |
| CADM2 | cell adhesion molecule 2 | -0.0424133 |
| RAD51B | RAD51 paralog B | -0.0421112 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0419709 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0416739 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0407762 |
| PHIP | pleckstrin homology domain interacting protein | -0.040638 |
| UBC | ubiquitin C | -0.0396607 |
| RPS27A | ribosomal protein S27a | -0.0393858 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0388873 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0382961 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0381878 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.038159 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0372636 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0369213 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0367445 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0366174 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.036542 |
| RFX7 | regulatory factor X, 7 | -0.0362099 |
| PRELID2 | PRELI domain containing 2 | -0.034789 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0347071 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0346592 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0344171 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0341578 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0322723 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0321465 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0317988 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.031506 |
| RBM39 | RNA binding motif protein 39 | -0.0313244 |
| TFG | TRK-fused gene | -0.0311659 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0310948 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0306673 |
| SRP54 | signal recognition particle 54kDa | -0.0305592 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0302118 |
| EMP1 | epithelial membrane protein 1 | -0.0301021 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0300995 |
| BTG3 | BTG family, member 3 | -0.0300683 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0298627 |
| XPO1 | exportin 1 | -0.029794 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0297363 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0295945 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0295874 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0293857 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0293693 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0293127 |
| GNAS | GNAS complex locus | -0.0292337 |
| PRTG | protogenin | -0.0290477 |
| RTN4 | reticulon 4 | -0.0289461 |
| PCDH9 | protocadherin 9 | -0.0287159 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0285592 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0284873 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0284622 |
| MAP4 | microtubule-associated protein 4 | -0.0284597 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0282689 |
| ANK2 | ankyrin 2, neuronal | -0.0281946 |
| THOC2 | THO complex 2 | -0.0281536 |
| ZNF148 | zinc finger protein 148 | -0.0278865 |
| COL3A1 | collagen, type III, alpha 1 | -0.0277382 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.027527 |
| DKC1 | dyskeratosis congenita 1, dyskerin | -0.0272867 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0271977 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0270621 |
| HMGA2 | high mobility group AT-hook 2 | -0.0269561 |
| RPL5 | ribosomal protein L5 | -0.0269182 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0267545 |
| RBM20 | RNA binding motif protein 20 | -0.0266987 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0266011 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.026558 |
| TNPO3 | transportin 3 | -0.0264397 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.026245 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0261057 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0260046 |
| POTEF | POTE ankyrin domain family, member F | -0.0259645 |
| POGZ | pogo transposable element with ZNF domain | -0.0259051 |
| UBN2 | ubinuclein 2 | -0.0258511 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.025807 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0256397 |
| GOLGA4 | golgin A4 | -0.0255891 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0253902 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0253862 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0252442 |
