| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.181229 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.140512 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.10661 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.075507 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0711768 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0664476 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0655539 |
| PLEC | plectin | 0.0654177 |
| SEPTIN9 | septin 9 | 0.0635207 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0616703 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0515916 |
| SMAD3 | SMAD family member 3 | 0.0496334 |
| NONO | non-POU domain containing, octamer-binding | 0.0474863 |
| TMSB10 | thymosin beta 10 | 0.0467146 |
| RPL3 | ribosomal protein L3 | 0.0461209 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0457849 |
| ANKRD11 | ankyrin repeat domain 11 | 0.044411 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.04149 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0412577 |
| PTMA | prothymosin, alpha | 0.0392053 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.038744 |
| MT2A | metallothionein 2A | 0.0379106 |
| NCOR2 | nuclear receptor corepressor 2 | 0.037088 |
| ANGPTL4 | angiopoietin-like 4 | 0.0358115 |
| RPL35A | ribosomal protein L35a | 0.0337259 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.0337158 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0334691 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0327601 |
| VEGFA | vascular endothelial growth factor A | 0.0320352 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.031233 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0304112 |
| APP | amyloid beta (A4) precursor protein | 0.0302364 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.029406 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0293189 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0291343 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0289761 |
| CLTA | clathrin, light chain A | 0.0288927 |
| SET | SET nuclear proto-oncogene | 0.0285398 |
| FOSL1 | FOS-like antigen 1 | 0.0284735 |
| NAV2 | neuron navigator 2 | 0.0280828 |
| TMSB4X | thymosin beta 4, X-linked | 0.0280642 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0277294 |
| RPL23 | ribosomal protein L23 | 0.0267458 |
| YBX1 | Y box binding protein 1 | 0.0266321 |
| AFDN | afadin, adherens junction formation factor | 0.0265341 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0264139 |
| MSN | moesin | 0.0263465 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0259924 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0259135 |
| AFAP1 | actin filament associated protein 1 | 0.0258716 |
| RPS3 | ribosomal protein S3 | 0.0256833 |
| FLNB | filamin B, beta | 0.0255009 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0254483 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0252844 |
| FLNA | filamin A, alpha | 0.0250733 |
| SFTPA2 | surfactant protein A2 | 0.0250145 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0246439 |
| CEP250 | centrosomal protein 250kDa | 0.0235492 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0229821 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0225083 |
| RPL37 | ribosomal protein L37 | 0.0223008 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0222877 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0222344 |
| RPL4 | ribosomal protein L4 | 0.022143 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0220774 |
| RPL37A | ribosomal protein L37a | 0.0220424 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0216653 |
| CTBP2 | C-terminal binding protein 2 | 0.0216048 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0215972 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0215662 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0215506 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0214668 |
| RPS19 | ribosomal protein S19 | 0.0214144 |
| CALR | calreticulin | 0.021386 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0210671 |
| RPL11 | ribosomal protein L11 | 0.0210476 |
| KRT18 | keratin 18, type I | 0.0209723 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0207921 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0207669 |
| KRT8 | keratin 8, type II | 0.0206304 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0205164 |
| CPNE1 | copine I | 0.0202433 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0202121 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0201952 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0201246 |
| ACTN1 | actinin, alpha 1 | 0.0201222 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.02008 |
| ACTN4 | actinin, alpha 4 | 0.0199702 |
| CMIP | c-Maf inducing protein | 0.0199153 |
| LMNA | lamin A/C | 0.0194328 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.019407 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0194047 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0193034 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0191402 |
| PHRF1 | PHD and ring finger domains 1 | 0.0190417 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0189792 |
| RPS17 | ribosomal protein S17 | 0.0188127 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0186022 |
| RPLP2 | ribosomal protein, large, P2 | 0.0185938 |
| HYOU1 | hypoxia up-regulated 1 | 0.0184809 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.36701 |
| VCL | vinculin | -0.14616 |
| VIM | vimentin | -0.0973841 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0900503 |
| CD44 | CD44 molecule (Indian blood group) | -0.0798677 |
| JMJD1C | jumonji domain containing 1C | -0.0694199 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.063387 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0629414 |
| TMEM123 | transmembrane protein 123 | -0.0619605 |
| ZFP36 | ZFP36 ring finger protein | -0.0559024 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0536096 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0499912 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0490604 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0475626 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0468399 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0459864 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0450436 |
| NF1 | neurofibromin 1 | -0.0441162 |
| SBF2 | SET binding factor 2 | -0.0430231 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0421921 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0416123 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0384582 |
| VMP1 | vacuole membrane protein 1 | -0.0367686 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0364671 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0355663 |
| UBC | ubiquitin C | -0.0347904 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0347014 |
| AHNAK | AHNAK nucleoprotein | -0.0343155 |
| HMGA1 | high mobility group AT-hook 1 | -0.0337809 |
| WASF2 | WAS protein family, member 2 | -0.0336802 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0329817 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0328068 |
| CANX | calnexin | -0.0326429 |
| ANXA2 | annexin A2 | -0.032421 |
| ZNF780B | zinc finger protein 780B | -0.0323161 |
| ERBIN | erbb2 interacting protein | -0.0321679 |
| ZNF644 | zinc finger protein 644 | -0.031981 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0305798 |
| ITGAV | integrin, alpha V | -0.0304997 |
| RTN4 | reticulon 4 | -0.0300723 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.029845 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0298258 |
| RASAL2 | RAS protein activator like 2 | -0.0294939 |
| DSTN | destrin (actin depolymerizing factor) | -0.0289139 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0284971 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0281529 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0280532 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0277519 |
| CDK13 | cyclin-dependent kinase 13 | -0.0275508 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.027234 |
| MAP4 | microtubule-associated protein 4 | -0.0269723 |
| PHF14 | PHD finger protein 14 | -0.0268791 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0266504 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0263922 |
| HMGA2 | high mobility group AT-hook 2 | -0.0260514 |
| TAOK1 | TAO kinase 1 | -0.026022 |
| EHBP1 | EH domain binding protein 1 | -0.0257746 |
| MAP1B | microtubule-associated protein 1B | -0.0256051 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0252655 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0252342 |
| IPO7 | importin 7 | -0.0251869 |
| TCF12 | transcription factor 12 | -0.0250811 |
| CCND1 | cyclin D1 | -0.0247597 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0241393 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0241178 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0239783 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0235672 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0234601 |
| OSMR | oncostatin M receptor | -0.0230219 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0229099 |
| RPLP0 | ribosomal protein, large, P0 | -0.0228971 |
| DEK | DEK proto-oncogene | -0.0224962 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0222315 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0222011 |
| USP34 | ubiquitin specific peptidase 34 | -0.0217485 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0216385 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0215187 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0213092 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0212721 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0211335 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0211042 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0209388 |
| GPHN | gephyrin | -0.0208553 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0208185 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0207237 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0207231 |
| RDX | radixin | -0.0205051 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0205007 |
| MYO1E | myosin IE | -0.0204423 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0203873 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0203678 |
| FRMD5 | FERM domain containing 5 | -0.0200917 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0199617 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0197855 |
| SEPTIN7 | septin 7 | -0.0197355 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0197213 |
| THOC2 | THO complex 2 | -0.0195295 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0194919 |
| EGFR | epidermal growth factor receptor | -0.0194548 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0194241 |
