| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | 0.164774 |
| KRT8 | keratin 8, type II | 0.128853 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.117362 |
| TMSB4X | thymosin beta 4, X-linked | 0.116983 |
| LAMB3 | laminin, beta 3 | 0.108121 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.105113 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.103135 |
| PLAU | plasminogen activator, urokinase | 0.102054 |
| NDRG1 | N-myc downstream regulated 1 | 0.0888692 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0880958 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0867036 |
| PLEC | plectin | 0.0774319 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0744709 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0738973 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0714768 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0703951 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0701393 |
| KRT18 | keratin 18, type I | 0.0693047 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0680698 |
| NAV2 | neuron navigator 2 | 0.0654065 |
| SMAD3 | SMAD family member 3 | 0.0644059 |
| TMSB10 | thymosin beta 10 | 0.0637246 |
| HLA-C | major histocompatibility complex, class I, C | 0.0636873 |
| KRT7 | keratin 7, type II | 0.0633709 |
| ANXA11 | annexin A11 | 0.0620568 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0590902 |
| B2M | beta-2-microglobulin | 0.0575679 |
| LDHA | lactate dehydrogenase A | 0.0559486 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0541619 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0534764 |
| NONO | non-POU domain containing, octamer-binding | 0.0522042 |
| PGK1 | phosphoglycerate kinase 1 | 0.0521645 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0521446 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0520312 |
| VEGFA | vascular endothelial growth factor A | 0.0503472 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0500365 |
| AFDN | afadin, adherens junction formation factor | 0.0488566 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0478658 |
| SQSTM1 | sequestosome 1 | 0.0476382 |
| HLA-A | major histocompatibility complex, class I, A | 0.0460521 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0457273 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0449223 |
| FOSL1 | FOS-like antigen 1 | 0.0438304 |
| ARGLU1 | arginine and glutamate rich 1 | 0.043421 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0426336 |
| RPL3 | ribosomal protein L3 | 0.0424978 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0418722 |
| TGM2 | transglutaminase 2 | 0.0414268 |
| SDC4 | syndecan 4 | 0.0404915 |
| YBX3 | Y box binding protein 3 | 0.0396414 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0387748 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0387297 |
| ARRDC3 | arrestin domain containing 3 | 0.0384007 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0378307 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0374307 |
| AHNAK | AHNAK nucleoprotein | 0.0364773 |
| AFAP1 | actin filament associated protein 1 | 0.0361094 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0359267 |
| G0S2 | G0/G1 switch 2 | 0.0358474 |
| EZR | ezrin | 0.0354769 |
| LAMC2 | laminin, gamma 2 | 0.035073 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0349842 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0341456 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0340681 |
| RLIM | ring finger protein, LIM domain interacting | 0.0332512 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0331892 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0329845 |
| OGA | O-GlcNAcase | 0.0329603 |
| YBX1 | Y box binding protein 1 | 0.0327679 |
| ADAR | adenosine deaminase, RNA-specific | 0.0322368 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0321359 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0318256 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0316347 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0314711 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0314162 |
| FLNB | filamin B, beta | 0.0313229 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0312857 |
| MYO5B | myosin VB | 0.0311815 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0309518 |
| RNF213 | ring finger protein 213 | 0.0308947 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0306577 |
| MED15 | mediator complex subunit 15 | 0.0304256 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0302155 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0297939 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0295429 |
| TJP2 | tight junction protein 2 | 0.0294876 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0292144 |
| TPM4 | tropomyosin 4 | 0.0289859 |
| PLAT | plasminogen activator, tissue | 0.0289085 |
| PKM | pyruvate kinase, muscle | 0.0285062 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0284348 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0281199 |
| WDR45B | WD repeat domain 45B | 0.028042 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0279384 |
| EFHD2 | EF-hand domain family, member D2 | 0.027795 |
| CPNE1 | copine I | 0.0276261 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0272697 |
| CEP250 | centrosomal protein 250kDa | 0.0270434 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0270134 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0266817 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.297441 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0812144 |
| INTS6 | integrator complex subunit 6 | -0.0707065 |
| HMGA1 | high mobility group AT-hook 1 | -0.066217 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0647904 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0638988 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0541559 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0535171 |
| LMO7 | LIM domain 7 | -0.0532013 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0504288 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0486161 |
| ANXA2 | annexin A2 | -0.0450508 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.042541 |
| GOLGB1 | golgin B1 | -0.0414428 |
| EGFR | epidermal growth factor receptor | -0.041339 |
| PLSCR1 | phospholipid scramblase 1 | -0.038801 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.038486 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0384554 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0375457 |
| PHF3 | PHD finger protein 3 | -0.0362236 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0356386 |
| EFNA5 | ephrin-A5 | -0.0351466 |
| BPTF | bromodomain PHD finger transcription factor | -0.0332951 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0326435 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0326356 |
| DSG2 | desmoglein 2 | -0.0324572 |
| GOLGA4 | golgin A4 | -0.0315859 |
| SMC4 | structural maintenance of chromosomes 4 | -0.03069 |
| RPS8 | ribosomal protein S8 | -0.0294282 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.0292032 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0290819 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0288374 |
| POTEF | POTE ankyrin domain family, member F | -0.0282729 |
| CDK13 | cyclin-dependent kinase 13 | -0.0280557 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0279401 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0273721 |
| EHBP1 | EH domain binding protein 1 | -0.0266497 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0262172 |
| RPS15 | ribosomal protein S15 | -0.0261777 |
| CANX | calnexin | -0.025903 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0258247 |
| RASAL2 | RAS protein activator like 2 | -0.0254573 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0252533 |
| MTDH | metadherin | -0.0250465 |
| USP34 | ubiquitin specific peptidase 34 | -0.0250275 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0247819 |
| DIAPH3 | diaphanous-related formin 3 | -0.024748 |
| HMGB1 | high mobility group box 1 | -0.0245276 |
| RPL21 | ribosomal protein L21 | -0.0244464 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0244007 |
| CLDN1 | claudin 1 | -0.024366 |
| TCF12 | transcription factor 12 | -0.0241801 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0239173 |
| PTMA | prothymosin, alpha | -0.0238536 |
| NF1 | neurofibromin 1 | -0.0236049 |
| RPS27A | ribosomal protein S27a | -0.0234759 |
| DEK | DEK proto-oncogene | -0.0232104 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0231371 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0231276 |
| CD2AP | CD2-associated protein | -0.0230925 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | -0.0228355 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0227906 |
| MKI67 | marker of proliferation Ki-67 | -0.0226532 |
| FN1 | fibronectin 1 | -0.0225008 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0223418 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0222099 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0220738 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0217992 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0217474 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0217226 |
| ERBIN | erbb2 interacting protein | -0.0216263 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0215748 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0214875 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0214576 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | -0.0213526 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0211611 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0208474 |
| RTN3 | reticulon 3 | -0.0207166 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0206042 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0204969 |
| RPL8 | ribosomal protein L8 | -0.0204861 |
| ZNF638 | zinc finger protein 638 | -0.0204345 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0203592 |
| NABP1 | nucleic acid binding protein 1 | -0.0203446 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.020312 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0202426 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0202256 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0202048 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0202024 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.019995 |
| GNAS | GNAS complex locus | -0.0199661 |
| MAP4 | microtubule-associated protein 4 | -0.0199397 |
| RTKN2 | rhotekin 2 | -0.0198838 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0195923 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0194573 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0193383 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.019257 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0191931 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0191054 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0190935 |
