| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0906946 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0837808 |
| LAMB3 | laminin, beta 3 | 0.0789674 |
| SET | SET nuclear proto-oncogene | 0.0718016 |
| RPL3 | ribosomal protein L3 | 0.0664839 |
| RPL4 | ribosomal protein L4 | 0.062744 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0614413 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0589114 |
| PTMA | prothymosin, alpha | 0.0576731 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0576551 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0551616 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0536042 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0529402 |
| TXNRD1 | thioredoxin reductase 1 | 0.049759 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0487766 |
| OGA | O-GlcNAcase | 0.0479336 |
| RPS12 | ribosomal protein S12 | 0.0474803 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0459155 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0446927 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0425994 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0416894 |
| RPL37A | ribosomal protein L37a | 0.041134 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0401749 |
| ENO1 | enolase 1, (alpha) | 0.0397676 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.039641 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0395476 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0391385 |
| ACTN1 | actinin, alpha 1 | 0.0379865 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0372092 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0370583 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0369651 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0366511 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0363507 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0359866 |
| RPL26 | ribosomal protein L26 | 0.0359126 |
| CEP250 | centrosomal protein 250kDa | 0.0356519 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0348683 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0346701 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0343784 |
| RPL13A | ribosomal protein L13a | 0.0341923 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0325985 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 0.0319848 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0318847 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0315034 |
| YEATS2 | YEATS domain containing 2 | 0.0313245 |
| CAPRIN2 | caprin family member 2 | 0.0307816 |
| RPS18 | ribosomal protein S18 | 0.0300989 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0299732 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0298439 |
| RPS17 | ribosomal protein S17 | 0.0293121 |
| RPS3 | ribosomal protein S3 | 0.0292252 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0291628 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0291169 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0290145 |
| GPR107 | G protein-coupled receptor 107 | 0.028575 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0285736 |
| FLNA | filamin A, alpha | 0.0284419 |
| NONO | non-POU domain containing, octamer-binding | 0.0284283 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0283478 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0283112 |
| PGK1 | phosphoglycerate kinase 1 | 0.0282623 |
| PFKP | phosphofructokinase, platelet | 0.028026 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0278397 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0278173 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.027811 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0277446 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.027656 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0275031 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0274072 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0274028 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0271983 |
| RPL35 | ribosomal protein L35 | 0.0267786 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0267224 |
| HDAC9 | histone deacetylase 9 | 0.0263053 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0262503 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0260848 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0259451 |
| JUN | jun proto-oncogene | 0.025909 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0251957 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0251919 |
| RPL11 | ribosomal protein L11 | 0.0247548 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0245598 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.024519 |
| SETX | senataxin | 0.0244639 |
| KLC1 | kinesin light chain 1 | 0.0243259 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0241716 |
| DIDO1 | death inducer-obliterator 1 | 0.02408 |
| AFDN | afadin, adherens junction formation factor | 0.0239583 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0236553 |
| RPS15A | ribosomal protein S15a | 0.0234938 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0233815 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0233261 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.023298 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.0229853 |
| KIF5B | kinesin family member 5B | 0.0229133 |
| CCNY | cyclin Y | 0.0225633 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0225255 |
| RPS24 | ribosomal protein S24 | 0.0224178 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0223287 |
| SMTN | smoothelin | 0.0222851 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.183142 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.172258 |
| FRMD6 | FERM domain containing 6 | -0.097895 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0937296 |
| ZNF438 | zinc finger protein 438 | -0.0846871 |
| NABP1 | nucleic acid binding protein 1 | -0.0834408 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.075706 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0739103 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0738357 |
| HMGA1 | high mobility group AT-hook 1 | -0.0734248 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0731696 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0695889 |
| HMGA2 | high mobility group AT-hook 2 | -0.0686069 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0655615 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0644865 |
| NAV3 | neuron navigator 3 | -0.0644275 |
| JMJD1C | jumonji domain containing 1C | -0.0581648 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0542053 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0516938 |
| BNC2 | basonuclin 2 | -0.0500639 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0492874 |
| RPL8 | ribosomal protein L8 | -0.0483737 |
| DIAPH3 | diaphanous-related formin 3 | -0.0480109 |
| FTL | ferritin, light polypeptide | -0.0473886 |
| ANK2 | ankyrin 2, neuronal | -0.0471558 |
| FHIT | fragile histidine triad | -0.046099 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0457571 |
| MT2A | metallothionein 2A | -0.0455231 |
| POTEF | POTE ankyrin domain family, member F | -0.0446462 |
| MTAP | methylthioadenosine phosphorylase | -0.0444996 |
| SP100 | SP100 nuclear antigen | -0.0443274 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0439649 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0433819 |
| LDHA | lactate dehydrogenase A | -0.0426478 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0421838 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0417219 |
| ERBIN | erbb2 interacting protein | -0.0410886 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0403791 |
| PFN1 | profilin 1 | -0.0402456 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0400641 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0393831 |
| TTR | transthyretin | -0.037039 |
| INTS6 | integrator complex subunit 6 | -0.0347065 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0346224 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0338988 |
| BBX | bobby sox homolog (Drosophila) | -0.0327174 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0326168 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0323834 |
| DIAPH2 | diaphanous-related formin 2 | -0.0307899 |
| DENND4A | DENN/MADD domain containing 4A | -0.0303287 |
| CCNL1 | cyclin L1 | -0.0302648 |
| SETD5 | SET domain containing 5 | -0.0300982 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0294481 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0292086 |
| TRAM1 | translocation associated membrane protein 1 | -0.0291681 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0291461 |
| RYBP | RING1 and YY1 binding protein | -0.0290798 |
| CPNE3 | copine III | -0.0288068 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0285601 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0284563 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0282759 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0276512 |
| PARD3 | par-3 family cell polarity regulator | -0.0276025 |
| ACTG1 | actin gamma 1 | -0.0275574 |
| TMEM87A | transmembrane protein 87A | -0.027394 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0273535 |
| RPLP0 | ribosomal protein, large, P0 | -0.0269569 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.026499 |
| USP15 | ubiquitin specific peptidase 15 | -0.0263991 |
| DEK | DEK proto-oncogene | -0.0261672 |
| SGMS2 | sphingomyelin synthase 2 | -0.0260895 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0258598 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.025431 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0254028 |
| CD68 | CD68 molecule | -0.0253666 |
| ANXA2 | annexin A2 | -0.0251257 |
| CANX | calnexin | -0.0250728 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0247568 |
| TCF12 | transcription factor 12 | -0.0247468 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0245977 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0244192 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0244056 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.024323 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0240111 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0237007 |
| DGKH | diacylglycerol kinase, eta | -0.0236607 |
| AHNAK | AHNAK nucleoprotein | -0.0235919 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0235717 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0235693 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0232483 |
| ZNF292 | zinc finger protein 292 | -0.0229621 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0228574 |
| SEPTIN11 | septin 11 | -0.022739 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0227199 |
| MYRFL | myelin regulatory factor-like | -0.0223908 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0222316 |
| S100A10 | S100 calcium binding protein A10 | -0.0221299 |
| RPS23 | ribosomal protein S23 | -0.0219631 |
| SDCBP | syndecan binding protein (syntenin) | -0.0218447 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0215117 |
