| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.153969 |
| PGK1 | phosphoglycerate kinase 1 | 0.128026 |
| VIM | vimentin | 0.122643 |
| COL7A1 | collagen, type VII, alpha 1 | 0.108853 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0997281 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0892689 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.084295 |
| VEGFA | vascular endothelial growth factor A | 0.0822401 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0745985 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0737398 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.070022 |
| FAM20C | family with sequence similarity 20, member C | 0.0651153 |
| PLEC | plectin | 0.0620775 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0608165 |
| NDRG1 | N-myc downstream regulated 1 | 0.0583526 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0576045 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0573344 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0558951 |
| NONO | non-POU domain containing, octamer-binding | 0.0548299 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0512769 |
| COL5A1 | collagen, type V, alpha 1 | 0.0502384 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0488931 |
| FLNA | filamin A, alpha | 0.0485427 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0479942 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0478433 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0474381 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0473024 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0464167 |
| RLIM | ring finger protein, LIM domain interacting | 0.0449531 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0441682 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0436691 |
| FLNB | filamin B, beta | 0.0428805 |
| CALR | calreticulin | 0.0418165 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0393753 |
| ACTN1 | actinin, alpha 1 | 0.0391858 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0386342 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0383039 |
| MLPH | melanophilin | 0.0371019 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0370757 |
| HLA-C | major histocompatibility complex, class I, C | 0.0362533 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0354014 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0346382 |
| TMEM178B | transmembrane protein 178B | 0.0343798 |
| DIDO1 | death inducer-obliterator 1 | 0.0343708 |
| LMNA | lamin A/C | 0.0341915 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0339307 |
| CEP250 | centrosomal protein 250kDa | 0.0338296 |
| TPM1 | tropomyosin 1 (alpha) | 0.0337885 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0336847 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0331136 |
| FMNL2 | formin-like 2 | 0.0330015 |
| C1D | C1D nuclear receptor corepressor | 0.0326763 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0324989 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0323091 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0316858 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0316593 |
| CD109 | CD109 molecule | 0.0314878 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0313497 |
| APP | amyloid beta (A4) precursor protein | 0.031316 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0312229 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0306162 |
| MMP2 | matrix metallopeptidase 2 | 0.0300916 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0300493 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0297577 |
| TMSB4X | thymosin beta 4, X-linked | 0.0293606 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.0290077 |
| INSIG2 | insulin induced gene 2 | 0.0289001 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.028712 |
| NAV2 | neuron navigator 2 | 0.0287065 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0282543 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0282109 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0280922 |
| MSN | moesin | 0.0275465 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0274221 |
| RPL3 | ribosomal protein L3 | 0.0273463 |
| MED15 | mediator complex subunit 15 | 0.0271465 |
| PER1 | period circadian clock 1 | 0.0271096 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0270655 |
| FAM13A | family with sequence similarity 13, member A | 0.0268188 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0267291 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0261525 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0260519 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0257048 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 0.025567 |
| TGM2 | transglutaminase 2 | 0.0254596 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0252123 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0250546 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0249964 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0248652 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0248582 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0247297 |
| RPL4 | ribosomal protein L4 | 0.0246846 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0245286 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0244574 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0242179 |
| RPN1 | ribophorin I | 0.0241802 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0239359 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0236336 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0236019 |
| SEPTIN2 | septin 2 | 0.0235944 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.403382 |
| FN1 | fibronectin 1 | -0.10513 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0888299 |
| CD44 | CD44 molecule (Indian blood group) | -0.0771354 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0723564 |
| STC1 | stanniocalcin 1 | -0.0722919 |
| FTL | ferritin, light polypeptide | -0.0678029 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.062873 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0612686 |
| MT2A | metallothionein 2A | -0.0568396 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0554948 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0542478 |
| COL1A1 | collagen, type I, alpha 1 | -0.054024 |
| GOLGA4 | golgin A4 | -0.0512976 |
| B2M | beta-2-microglobulin | -0.0506683 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0487302 |
| NRP1 | neuropilin 1 | -0.045859 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0458257 |
| SP100 | SP100 nuclear antigen | -0.0445568 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0435445 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.043296 |
| POTEF | POTE ankyrin domain family, member F | -0.0427109 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0420873 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.041965 |
| FRMD4A | FERM domain containing 4A | -0.0413687 |
| CDCP1 | CUB domain containing protein 1 | -0.039497 |
| USP34 | ubiquitin specific peptidase 34 | -0.0389085 |
| MAP4 | microtubule-associated protein 4 | -0.0370619 |
| UBC | ubiquitin C | -0.0347083 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.034588 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0342803 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0340668 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0340076 |
| H1-0 | H1.0 linker histone | -0.0333954 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0327352 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0322707 |
| SVIL | supervillin | -0.0320081 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0316327 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0296717 |
| RPS2 | ribosomal protein S2 | -0.0293192 |
| CANX | calnexin | -0.029211 |
| IER3 | immediate early response 3 | -0.0290226 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0289329 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.028537 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0284699 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0283894 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0283114 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0279906 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0279578 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0279298 |
| SEPTIN7 | septin 7 | -0.027608 |
| TCF12 | transcription factor 12 | -0.0274497 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0273784 |
| DSTN | destrin (actin depolymerizing factor) | -0.0271908 |
| RYBP | RING1 and YY1 binding protein | -0.0271489 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0270132 |
| CLTC | clathrin, heavy chain (Hc) | -0.0265647 |
| FHIT | fragile histidine triad | -0.0259828 |
| LOX | lysyl oxidase | -0.0258 |
| SETD5 | SET domain containing 5 | -0.0257844 |
| S100A10 | S100 calcium binding protein A10 | -0.0257588 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.025298 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0249622 |
| FBN1 | fibrillin 1 | -0.0246145 |
| WASF2 | WAS protein family, member 2 | -0.0245002 |
| CLIC4 | chloride intracellular channel 4 | -0.0244163 |
| SEC24A | SEC24 family member A | -0.0242456 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0241968 |
| RPS6 | ribosomal protein S6 | -0.023991 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.023747 |
| GNAS | GNAS complex locus | -0.0237267 |
| THY1 | Thy-1 cell surface antigen | -0.0236698 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0235658 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0234611 |
| NKTR | natural killer cell triggering receptor | -0.0232992 |
| XAF1 | XIAP associated factor 1 | -0.023229 |
| IL1B | interleukin 1, beta | -0.0231719 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.023043 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0228758 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0227991 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0227826 |
| ZNF644 | zinc finger protein 644 | -0.0227169 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0226301 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0224107 |
| RPL32 | ribosomal protein L32 | -0.0223375 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.022258 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0222445 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0220969 |
| MTDH | metadherin | -0.0220309 |
| NF1 | neurofibromin 1 | -0.0218928 |
| GLG1 | golgi glycoprotein 1 | -0.0217551 |
| COL1A2 | collagen, type I, alpha 2 | -0.0217076 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0216546 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0216402 |
| ERBIN | erbb2 interacting protein | -0.0215035 |
| EXOC6B | exocyst complex component 6B | -0.0214534 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0213961 |
| ASPH | aspartate beta-hydroxylase | -0.0212627 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0212473 |
| VMP1 | vacuole membrane protein 1 | -0.0212327 |
