| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.124016 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.117786 |
| CHGB | chromogranin B | 0.115905 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.105384 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.105044 |
| LOC112694756 | uncharaterized LOC112694756 | 0.100049 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0996732 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0901121 |
| TMSB4X | thymosin beta 4, X-linked | 0.0861389 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0829275 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.079133 |
| CENPF | centromere protein F, 350/400kDa | 0.0743357 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0738947 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0677457 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0667185 |
| SCG2 | secretogranin II | 0.0661966 |
| RPL3 | ribosomal protein L3 | 0.0643812 |
| NDRG1 | N-myc downstream regulated 1 | 0.0643069 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0614672 |
| HMGB3 | high mobility group box 3 | 0.0611313 |
| NONO | non-POU domain containing, octamer-binding | 0.0600722 |
| MT2A | metallothionein 2A | 0.0594827 |
| RPL23 | ribosomal protein L23 | 0.0575299 |
| VEGFA | vascular endothelial growth factor A | 0.0575291 |
| ENO1 | enolase 1, (alpha) | 0.0571516 |
| RPS21 | ribosomal protein S21 | 0.056731 |
| SET | SET nuclear proto-oncogene | 0.0560108 |
| RPL37 | ribosomal protein L37 | 0.053462 |
| PTMA | prothymosin, alpha | 0.0511661 |
| PRELID3B | PRELI domain containing 3B | 0.0492544 |
| RPS6 | ribosomal protein S6 | 0.0478822 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0440875 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0436813 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.0427719 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0425304 |
| IRS2 | insulin receptor substrate 2 | 0.0420447 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0420014 |
| TMSB10 | thymosin beta 10 | 0.0413247 |
| ACTG1 | actin gamma 1 | 0.0410314 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0408694 |
| B2M | beta-2-microglobulin | 0.0405217 |
| RPL35 | ribosomal protein L35 | 0.0399247 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0392358 |
| RPS27 | ribosomal protein S27 | 0.0391977 |
| YBX1 | Y box binding protein 1 | 0.0391822 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.039031 |
| RPL37A | ribosomal protein L37a | 0.038922 |
| RPS17 | ribosomal protein S17 | 0.0383993 |
| GRAMD4 | GRAM domain containing 4 | 0.0380744 |
| RPS19 | ribosomal protein S19 | 0.0376146 |
| RPL11 | ribosomal protein L11 | 0.0375261 |
| FTL | ferritin, light polypeptide | 0.0374545 |
| RACK1 | receptor for activated C kinase 1 | 0.0370789 |
| TPM3 | tropomyosin 3 | 0.0367763 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.0356788 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0343519 |
| PNN | pinin, desmosome associated protein | 0.0341871 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0339619 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0338591 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0332522 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0330219 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.0326866 |
| ADAR | adenosine deaminase, RNA-specific | 0.0324027 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0323691 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0322409 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0320003 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0316729 |
| NAV1 | neuron navigator 1 | 0.0312121 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0312016 |
| CPE | carboxypeptidase E | 0.030967 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0303434 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0299449 |
| TSPYL2 | TSPY-like 2 | 0.0297966 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0297699 |
| RPL19 | ribosomal protein L19 | 0.0295916 |
| CEP250 | centrosomal protein 250kDa | 0.0295823 |
| HLA-A | major histocompatibility complex, class I, A | 0.0295402 |
| MAP1B | microtubule-associated protein 1B | 0.0292464 |
| PHF21A | PHD finger protein 21A | 0.0292073 |
| ZNF395 | zinc finger protein 395 | 0.0291676 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0291516 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0290206 |
| RPL36AL | ribosomal protein L36a-like | 0.0289256 |
| RPL36 | ribosomal protein L36 | 0.0287439 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0286526 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0286511 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0285328 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0281722 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0278551 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0273115 |
| RPS3 | ribosomal protein S3 | 0.0265712 |
| PKM | pyruvate kinase, muscle | 0.0264312 |
| RPL4 | ribosomal protein L4 | 0.0262806 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0260151 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0259919 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0250701 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0250434 |
| LMNB1 | lamin B1 | 0.0250264 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0249587 |
| MINK1 | misshapen-like kinase 1 | 0.0248938 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.118807 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.110436 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0782747 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0781939 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0686671 |
| TENM1 | teneurin transmembrane protein 1 | -0.0685532 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0639344 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0531857 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.05269 |
| GPC6 | glypican 6 | -0.0466963 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0416406 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0411756 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0406493 |
| GPHN | gephyrin | -0.0404653 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0384539 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0381311 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0374046 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0364926 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0362886 |
| STXBP5L | syntaxin binding protein 5-like | -0.033853 |
| HOMER1 | homer scaffolding protein 1 | -0.0338405 |
| NRG1 | neuregulin 1 | -0.0337319 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0337172 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0335354 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0332452 |
| INHBA | inhibin, beta A | -0.0332233 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0325447 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0323135 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -0.0323058 |
| DTNA | dystrobrevin, alpha | -0.0319656 |
| PDE10A | phosphodiesterase 10A | -0.0316985 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0316047 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0312467 |
| TUSC3 | tumor suppressor candidate 3 | -0.0311604 |
| NF1 | neurofibromin 1 | -0.0310431 |
| ZNF804A | zinc finger protein 804A | -0.0307949 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0307345 |
| SRP72 | signal recognition particle 72kDa | -0.030599 |
| VMP1 | vacuole membrane protein 1 | -0.0298834 |
| NBEA | neurobeachin | -0.0293644 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0290538 |
| GOLGA4 | golgin A4 | -0.0290093 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0287679 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0287296 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0286118 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0285088 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0285074 |
| SCFD2 | sec1 family domain containing 2 | -0.0277225 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0275957 |
| CDK13 | cyclin-dependent kinase 13 | -0.0275416 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0271489 |
| CANX | calnexin | -0.0271452 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0266573 |
| USP15 | ubiquitin specific peptidase 15 | -0.0262742 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | -0.0261301 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0261258 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | -0.0261149 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0259663 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.025646 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.025289 |
| GPATCH8 | G patch domain containing 8 | -0.0252027 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0248061 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0247886 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0245983 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0245774 |
| TTC19 | tetratricopeptide repeat domain 19 | -0.0244985 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0244232 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0244154 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0244114 |
| SGO2 | shugoshin 2 | -0.0243961 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0243709 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0242708 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0242192 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0241624 |
| PTCHD4 | patched domain containing 4 | -0.0241471 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0241183 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0238201 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0237749 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0237324 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0235575 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0235359 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0235149 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.023497 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0234835 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0234728 |
| RLF | rearranged L-myc fusion | -0.023069 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0230124 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.022618 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0224957 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0224706 |
| ATF6 | activating transcription factor 6 | -0.0224677 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.022331 |
| JMJD1C | jumonji domain containing 1C | -0.0221221 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0219827 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0219604 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0219224 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0219219 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0218727 |
| GOLGB1 | golgin B1 | -0.0217501 |
| HDAC2 | histone deacetylase 2 | -0.0216816 |
