| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.128054 |
| MSI2 | musashi RNA-binding protein 2 | 0.113493 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.110127 |
| FLNA | filamin A, alpha | 0.0851738 |
| PLEC | plectin | 0.0786112 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0782518 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0765943 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0742525 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0693795 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0660823 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.062809 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0617456 |
| FLNB | filamin B, beta | 0.0611757 |
| FMNL2 | formin-like 2 | 0.0608575 |
| PGK1 | phosphoglycerate kinase 1 | 0.0593189 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0592184 |
| ANGPTL4 | angiopoietin-like 4 | 0.0582814 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0572746 |
| CADM1 | cell adhesion molecule 1 | 0.0554744 |
| SFTPA2 | surfactant protein A2 | 0.0552275 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0538472 |
| VIM | vimentin | 0.0533706 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0531451 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0510754 |
| SEPTIN9 | septin 9 | 0.0508204 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0500218 |
| NLGN1 | neuroligin 1 | 0.0489759 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0485771 |
| RPL3 | ribosomal protein L3 | 0.0478719 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0465514 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0465393 |
| NONO | non-POU domain containing, octamer-binding | 0.046222 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0453057 |
| OGA | O-GlcNAcase | 0.0446349 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0432813 |
| CEP250 | centrosomal protein 250kDa | 0.0432734 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0417749 |
| CTBP2 | C-terminal binding protein 2 | 0.04171 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0416994 |
| CABIN1 | calcineurin binding protein 1 | 0.0412355 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0411458 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0406372 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0401783 |
| FAM13A | family with sequence similarity 13, member A | 0.0399993 |
| VEGFA | vascular endothelial growth factor A | 0.0399714 |
| ACTN1 | actinin, alpha 1 | 0.038978 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0388632 |
| PTMA | prothymosin, alpha | 0.0387109 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0382286 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0380502 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0374983 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0373345 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.037162 |
| HDAC4 | histone deacetylase 4 | 0.0364211 |
| LDHA | lactate dehydrogenase A | 0.0360901 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0355969 |
| HELZ | helicase with zinc finger | 0.0355503 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0349875 |
| DENND1A | DENN/MADD domain containing 1A | 0.0341931 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.034034 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.033607 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0330738 |
| YEATS2 | YEATS domain containing 2 | 0.0328646 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.032857 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0325178 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0323265 |
| RPL23 | ribosomal protein L23 | 0.0323177 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0319464 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0316413 |
| HPCAL1 | hippocalcin-like 1 | 0.0316111 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0313287 |
| PRELID2 | PRELI domain containing 2 | 0.0309947 |
| MED15 | mediator complex subunit 15 | 0.0309054 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0306021 |
| TMEM51 | transmembrane protein 51 | 0.0302757 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0302237 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0299488 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 0.0298873 |
| SMAD3 | SMAD family member 3 | 0.0297214 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0296875 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0293614 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0293604 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0292727 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0291261 |
| TMSB10 | thymosin beta 10 | 0.0288794 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0288463 |
| USP3 | ubiquitin specific peptidase 3 | 0.0287671 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0287564 |
| CD109 | CD109 molecule | 0.0287493 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0286947 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0286227 |
| WDR45B | WD repeat domain 45B | 0.0280359 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0280167 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0279452 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0277781 |
| HMG20B | high mobility group 20B | 0.0274089 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0270768 |
| PRRC2B | proline-rich coiled-coil 2B | 0.026827 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0266127 |
| DST | dystonin | 0.0262355 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195432 |
| FMN1 | formin 1 | -0.17462 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0877539 |
| TXNRD1 | thioredoxin reductase 1 | -0.0849416 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0668506 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0555729 |
| CCND1 | cyclin D1 | -0.0541915 |
| MAP4 | microtubule-associated protein 4 | -0.0535516 |
| CD44 | CD44 molecule (Indian blood group) | -0.0531193 |
| FRMD5 | FERM domain containing 5 | -0.051609 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0511063 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0492955 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0452433 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0435216 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0434607 |
| SQSTM1 | sequestosome 1 | -0.043026 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.039895 |
| TENM1 | teneurin transmembrane protein 1 | -0.0394512 |
| RASAL2 | RAS protein activator like 2 | -0.0388735 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0369186 |
| HDAC9 | histone deacetylase 9 | -0.036697 |
| ERBIN | erbb2 interacting protein | -0.0363411 |
| VMP1 | vacuole membrane protein 1 | -0.0363021 |
| POTEF | POTE ankyrin domain family, member F | -0.0348731 |
| CLTC | clathrin, heavy chain (Hc) | -0.0340419 |
| NRG3 | neuregulin 3 | -0.0335328 |
| RPS2 | ribosomal protein S2 | -0.0324525 |
| GOLGB1 | golgin B1 | -0.0310134 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0302086 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0298939 |
| GOLGA4 | golgin A4 | -0.029502 |
| TP63 | tumor protein p63 | -0.0292014 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0280605 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0277143 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0276095 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0273051 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0268803 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0268089 |
| PCNX4 | pecanex 4 | -0.0264826 |
| RUNX1 | runt-related transcription factor 1 | -0.0260993 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0255506 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0254035 |
| BPTF | bromodomain PHD finger transcription factor | -0.0250645 |
| FNIP1 | folliculin interacting protein 1 | -0.0249937 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0244131 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0243694 |
| EMP1 | epithelial membrane protein 1 | -0.0241449 |
| RPS6 | ribosomal protein S6 | -0.0240745 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0239734 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0238947 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0238912 |
| HMGA1 | high mobility group AT-hook 1 | -0.023802 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0237996 |
| IL6ST | interleukin 6 signal transducer | -0.0237037 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0234259 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0233427 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0228924 |
| RPS23 | ribosomal protein S23 | -0.0228288 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0226535 |
| PAPOLA | poly(A) polymerase alpha | -0.0225814 |
| COMMD10 | COMM domain containing 10 | -0.0225454 |
| PKP4 | plakophilin 4 | -0.0224697 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0220895 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0216643 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0214012 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.020823 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0206355 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0201974 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0200596 |
| MYO9A | myosin IXA | -0.020057 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0200288 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0197875 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0196239 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.0194248 |
| USP53 | ubiquitin specific peptidase 53 | -0.0192944 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0192623 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0192103 |
| CDK13 | cyclin-dependent kinase 13 | -0.0191638 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0191227 |
| MED13 | mediator complex subunit 13 | -0.0191205 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0189951 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.018966 |
| GPHN | gephyrin | -0.0189085 |
| IPO7 | importin 7 | -0.0188813 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | -0.0187748 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0187105 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0185463 |
| GPATCH8 | G patch domain containing 8 | -0.018469 |
| MYO1D | myosin ID | -0.0184524 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0184157 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0183836 |
| CENPF | centromere protein F, 350/400kDa | -0.0183758 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0182749 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0180755 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0180717 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.01802 |
| NF1 | neurofibromin 1 | -0.0179658 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0178941 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0178068 |
| WASF2 | WAS protein family, member 2 | -0.0177723 |
