| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.242437 |
| RPL3 | ribosomal protein L3 | 0.104393 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0964283 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0963733 |
| RPL35A | ribosomal protein L35a | 0.0892061 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0878158 |
| PGK1 | phosphoglycerate kinase 1 | 0.0778399 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.073306 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0726654 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0714626 |
| ACTG1 | actin gamma 1 | 0.0669155 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0576087 |
| RPL11 | ribosomal protein L11 | 0.0568699 |
| RPS19 | ribosomal protein S19 | 0.0564697 |
| RPLP0 | ribosomal protein, large, P0 | 0.0555434 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0548404 |
| NONO | non-POU domain containing, octamer-binding | 0.053965 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0537395 |
| ZNF292 | zinc finger protein 292 | 0.0514058 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0511003 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0496108 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0492481 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0492231 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0491957 |
| RPL13A | ribosomal protein L13a | 0.0482835 |
| PLXNA1 | plexin A1 | 0.0480649 |
| RBM39 | RNA binding motif protein 39 | 0.0477691 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0471509 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0467994 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0465921 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0465655 |
| QKI | QKI, KH domain containing, RNA binding | 0.0464915 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0454655 |
| RPS6 | ribosomal protein S6 | 0.0446916 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0446192 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0435668 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0434901 |
| EVI5 | ecotropic viral integration site 5 | 0.0428879 |
| NUP58 | nucleoporin 58 | 0.0420638 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0410783 |
| HLA-B | major histocompatibility complex, class I, B | 0.0398964 |
| MSI2 | musashi RNA-binding protein 2 | 0.0398853 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.039252 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0387862 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0387143 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0378228 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0376689 |
| RNF145 | ring finger protein 145 | 0.0374547 |
| YBX1 | Y box binding protein 1 | 0.0372806 |
| PTK2 | protein tyrosine kinase 2 | 0.0371189 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0358727 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0353837 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0353674 |
| PER1 | period circadian clock 1 | 0.034605 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0343169 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0339601 |
| RHEB | Ras homolog enriched in brain | 0.03385 |
| NFIA | nuclear factor I/A | 0.0336826 |
| FTL | ferritin, light polypeptide | 0.0332482 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0331704 |
| CDC73 | cell division cycle 73 | 0.0329629 |
| TFG | TRK-fused gene | 0.0329301 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.032806 |
| NBAS | neuroblastoma amplified sequence | 0.032793 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0327379 |
| CABIN1 | calcineurin binding protein 1 | 0.0326203 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0324013 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0323085 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0316144 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0315644 |
| WAC | WW domain containing adaptor with coiled-coil | 0.031258 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0312272 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0312079 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0306582 |
| GOLGA2 | golgin A2 | 0.0302805 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0301572 |
| B2M | beta-2-microglobulin | 0.0301266 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0299218 |
| CEP250 | centrosomal protein 250kDa | 0.0298636 |
| RPL9 | ribosomal protein L9 | 0.0295809 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0293821 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.029283 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0290818 |
| TMSB10 | thymosin beta 10 | 0.0289474 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0289362 |
| RPL19 | ribosomal protein L19 | 0.0287129 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0287022 |
| TMEM41B | transmembrane protein 41B | 0.0285914 |
| WDR43 | WD repeat domain 43 | 0.0284758 |
| MLEC | malectin | 0.0282565 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0281956 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0281343 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0281009 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0280162 |
| CCNL1 | cyclin L1 | 0.0279857 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0278057 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0277613 |
| FAM162A | family with sequence similarity 162, member A | 0.0277038 |
| SETD5 | SET domain containing 5 | 0.0276488 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0276381 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.287354 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.208844 |
| AHNAK | AHNAK nucleoprotein | -0.206305 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.16888 |
| UBC | ubiquitin C | -0.117027 |
| PKM | pyruvate kinase, muscle | -0.0915336 |
| BMP10 | bone morphogenetic protein 10 | -0.087089 |
| RPS27A | ribosomal protein S27a | -0.0607339 |
| CCND1 | cyclin D1 | -0.0591208 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0581583 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0547692 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0544354 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0543404 |
| ENO1 | enolase 1, (alpha) | -0.0523197 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0518559 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0507177 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0489354 |
| EGFR | epidermal growth factor receptor | -0.0470986 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0461627 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0446444 |
| VCL | vinculin | -0.0421063 |
| BMP2K | BMP2 inducible kinase | -0.0420988 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0409358 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0406014 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0377354 |
| NBEA | neurobeachin | -0.0376675 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0366118 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0350941 |
| HDAC9 | histone deacetylase 9 | -0.03497 |
| EZR | ezrin | -0.0348585 |
| MAP4 | microtubule-associated protein 4 | -0.0346441 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0339428 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0324474 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0323822 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0310327 |
| RPS2 | ribosomal protein S2 | -0.0308744 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0282564 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0279929 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.027882 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0274981 |
| POTEF | POTE ankyrin domain family, member F | -0.0268234 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.026766 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0265202 |
| RTN4 | reticulon 4 | -0.0262082 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0260281 |
| RPL14 | ribosomal protein L14 | -0.0254965 |
| FOXP1 | forkhead box P1 | -0.0253353 |
| TXNRD1 | thioredoxin reductase 1 | -0.0244167 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.024198 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0233537 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0227439 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0226142 |
| CCNI | cyclin I | -0.0218078 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.021018 |
| CEP350 | centrosomal protein 350kDa | -0.0207356 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0205436 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0205394 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0204436 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0201331 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0198147 |
| GLI3 | GLI family zinc finger 3 | -0.0196957 |
| RPL18 | ribosomal protein L18 | -0.0193377 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0192471 |
| DGKH | diacylglycerol kinase, eta | -0.0192327 |
| PDE7B | phosphodiesterase 7B | -0.0190782 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0186734 |
| ZNF638 | zinc finger protein 638 | -0.0186388 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0186004 |
| RHOA | ras homolog family member A | -0.0184379 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0182899 |
| TASOR2 | transcription activation suppressor family member 2 | -0.018224 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0180063 |
| MTAP | methylthioadenosine phosphorylase | -0.0179013 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0178686 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0178648 |
| DIAPH3 | diaphanous-related formin 3 | -0.0178635 |
| BPTF | bromodomain PHD finger transcription factor | -0.0178489 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0178139 |
| GPATCH8 | G patch domain containing 8 | -0.0177884 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0177639 |
| ZNF608 | zinc finger protein 608 | -0.0177027 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0176431 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0175488 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0174757 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.017462 |
| EXOC6B | exocyst complex component 6B | -0.017398 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0173183 |
| WASF2 | WAS protein family, member 2 | -0.0172604 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0171147 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0170867 |
| DEK | DEK proto-oncogene | -0.0170618 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0170161 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0169579 |
| ATP9B | ATPase, class II, type 9B | -0.0168674 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0168567 |
| ZNF106 | zinc finger protein 106 | -0.0168182 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0168138 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0167925 |
| ANXA1 | annexin A1 | -0.016782 |
| S100A10 | S100 calcium binding protein A10 | -0.0167171 |
