| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.295319 |
| COL6A3 | collagen, type VI, alpha 3 | 0.129741 |
| VEGFA | vascular endothelial growth factor A | 0.123275 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.12198 |
| HLA-B | major histocompatibility complex, class I, B | 0.119674 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.096109 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0879852 |
| NONO | non-POU domain containing, octamer-binding | 0.0872539 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0727105 |
| ADM | adrenomedullin | 0.0724731 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0720013 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0674164 |
| NAV2 | neuron navigator 2 | 0.0673326 |
| HLA-A | major histocompatibility complex, class I, A | 0.0668398 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0601607 |
| TMSB4X | thymosin beta 4, X-linked | 0.0563493 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0550701 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0535086 |
| CEP250 | centrosomal protein 250kDa | 0.0530298 |
| OGA | O-GlcNAcase | 0.050611 |
| MSN | moesin | 0.0485581 |
| PGK1 | phosphoglycerate kinase 1 | 0.0483216 |
| ZNF292 | zinc finger protein 292 | 0.0467094 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0458576 |
| ANLN | anillin, actin binding protein | 0.0451993 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0451785 |
| PTMA | prothymosin, alpha | 0.045072 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0449631 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0430414 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0417716 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.041243 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0400763 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0396803 |
| SMAD3 | SMAD family member 3 | 0.0392856 |
| ATP13A3 | ATPase type 13A3 | 0.0392485 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0392237 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0386483 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0386411 |
| SDC4 | syndecan 4 | 0.0380025 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0378297 |
| HLA-C | major histocompatibility complex, class I, C | 0.0374825 |
| DENND5A | DENN/MADD domain containing 5A | 0.0373435 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0369692 |
| CENPF | centromere protein F, 350/400kDa | 0.0365622 |
| AFDN | afadin, adherens junction formation factor | 0.0355953 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0355017 |
| RPL3 | ribosomal protein L3 | 0.0350766 |
| NDRG1 | N-myc downstream regulated 1 | 0.0345464 |
| SFTPA2 | surfactant protein A2 | 0.0342589 |
| APP | amyloid beta (A4) precursor protein | 0.0341164 |
| FLNA | filamin A, alpha | 0.0339219 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0326883 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0321497 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0317484 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0313101 |
| YBX3 | Y box binding protein 3 | 0.0307452 |
| PRRC2C | proline-rich coiled-coil 2C | 0.030206 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0301435 |
| RAI1 | retinoic acid induced 1 | 0.0296091 |
| HELZ | helicase with zinc finger | 0.0294996 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0293187 |
| SET | SET nuclear proto-oncogene | 0.0285819 |
| MKI67 | marker of proliferation Ki-67 | 0.0284103 |
| B2M | beta-2-microglobulin | 0.0283867 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0283823 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0276832 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0276171 |
| YBX1 | Y box binding protein 1 | 0.0271935 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0271229 |
| COL1A2 | collagen, type I, alpha 2 | 0.0269161 |
| PFKP | phosphofructokinase, platelet | 0.0267009 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0266728 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0265071 |
| MLPH | melanophilin | 0.026434 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.026429 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0263314 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0260712 |
| OPTN | optineurin | 0.0257894 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0255244 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0255128 |
| CADM1 | cell adhesion molecule 1 | 0.0254873 |
| RPL4 | ribosomal protein L4 | 0.02535 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0249909 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0249843 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0243772 |
| ARRDC3 | arrestin domain containing 3 | 0.0234936 |
| TMSB10 | thymosin beta 10 | 0.0234129 |
| FOSL1 | FOS-like antigen 1 | 0.0232992 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0232021 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.023126 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0231181 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0230657 |
| STC1 | stanniocalcin 1 | 0.0228296 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0227102 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0224242 |
| RPL23 | ribosomal protein L23 | 0.0223123 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0222686 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0222556 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0221805 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0221546 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.317786 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.136497 |
| VCL | vinculin | -0.101982 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0944789 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0891203 |
| HMGA2 | high mobility group AT-hook 2 | -0.0727435 |
| IER3 | immediate early response 3 | -0.0654172 |
| INTS6 | integrator complex subunit 6 | -0.0637336 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0610609 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0605994 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0588122 |
| HDAC9 | histone deacetylase 9 | -0.0570742 |
| FRMD4A | FERM domain containing 4A | -0.0515959 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0513186 |
| EXT1 | exostosin glycosyltransferase 1 | -0.050359 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0500598 |
| BICC1 | BicC family RNA binding protein 1 | -0.0487045 |
| GLIS3 | GLIS family zinc finger 3 | -0.0462856 |
| GOLGB1 | golgin B1 | -0.0455932 |
| NABP1 | nucleic acid binding protein 1 | -0.045314 |
| CANX | calnexin | -0.0444766 |
| FTL | ferritin, light polypeptide | -0.0442034 |
| FN1 | fibronectin 1 | -0.0435109 |
| PALLD | palladin, cytoskeletal associated protein | -0.0425038 |
| DIAPH2 | diaphanous-related formin 2 | -0.0411684 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0403415 |
| MAP4 | microtubule-associated protein 4 | -0.0401179 |
| KYNU | kynureninase | -0.0399477 |
| ATXN1 | ataxin 1 | -0.039736 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0387539 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0381156 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0378957 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0374926 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0372392 |
| CD44 | CD44 molecule (Indian blood group) | -0.0368706 |
| VMP1 | vacuole membrane protein 1 | -0.0351369 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0349815 |
| SMYD3 | SET and MYND domain containing 3 | -0.034974 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0347486 |
| FNIP1 | folliculin interacting protein 1 | -0.0344574 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0344535 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0340916 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0339934 |
| BPTF | bromodomain PHD finger transcription factor | -0.0338501 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0323871 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0321405 |
| GPC6 | glypican 6 | -0.0313578 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0301127 |
| RPS23 | ribosomal protein S23 | -0.0301106 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0300671 |
| UBC | ubiquitin C | -0.0298195 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0297592 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0293668 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0293075 |
| CDH13 | cadherin 13 | -0.0287584 |
| MAP1B | microtubule-associated protein 1B | -0.0287412 |
| AHNAK | AHNAK nucleoprotein | -0.028506 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0278246 |
| SQSTM1 | sequestosome 1 | -0.0267146 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0265696 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0259181 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0257469 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0257376 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0256497 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0253002 |
| RTN3 | reticulon 3 | -0.0245486 |
| PHF3 | PHD finger protein 3 | -0.0243293 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0242028 |
| ANXA2 | annexin A2 | -0.0241911 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.0237725 |
| EGFR | epidermal growth factor receptor | -0.0231037 |
| JMJD1C | jumonji domain containing 1C | -0.0228715 |
| ASPH | aspartate beta-hydroxylase | -0.0228459 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0225636 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0224668 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0221237 |
| TMEM263 | transmembrane protein 263 | -0.0219255 |
| TMEM132D | transmembrane protein 132D | -0.0216684 |
| RND3 | Rho family GTPase 3 | -0.0215134 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0210171 |
| WASF2 | WAS protein family, member 2 | -0.0210138 |
| CDK13 | cyclin-dependent kinase 13 | -0.0208506 |
| PLIN2 | perilipin 2 | -0.0207611 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0207602 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.0205914 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0204905 |
| EHBP1 | EH domain binding protein 1 | -0.0201837 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0201711 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0201248 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0200931 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.019954 |
| TBCA | tubulin folding cofactor A | -0.0193 |
| RASAL2 | RAS protein activator like 2 | -0.0192859 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0191622 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0190793 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0190758 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0190537 |
| RIGI | RNA sensor RIG-I | -0.0190451 |
| TAOK1 | TAO kinase 1 | -0.0189234 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0188041 |
