| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.359086 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0968328 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0935306 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0880139 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0602998 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0536152 |
| MSN | moesin | 0.0517556 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0508052 |
| B2M | beta-2-microglobulin | 0.0498372 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0491956 |
| MT1X | metallothionein 1X | 0.048577 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0482367 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0481413 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0480906 |
| HLA-B | major histocompatibility complex, class I, B | 0.0477045 |
| HLA-A | major histocompatibility complex, class I, A | 0.0469003 |
| TMSB10 | thymosin beta 10 | 0.0441408 |
| TMSB4X | thymosin beta 4, X-linked | 0.0437197 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0420037 |
| NDRG1 | N-myc downstream regulated 1 | 0.0406381 |
| FRMD6 | FERM domain containing 6 | 0.0402704 |
| MT2A | metallothionein 2A | 0.0379425 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0377657 |
| VEGFA | vascular endothelial growth factor A | 0.0362603 |
| PTMA | prothymosin, alpha | 0.0362218 |
| FLNA | filamin A, alpha | 0.0361196 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0360966 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0359337 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0351018 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0347607 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0331789 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0327542 |
| NONO | non-POU domain containing, octamer-binding | 0.0327387 |
| HLA-C | major histocompatibility complex, class I, C | 0.0325725 |
| TPM3 | tropomyosin 3 | 0.0319534 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0308766 |
| EFNA5 | ephrin-A5 | 0.0304956 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0294353 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0292881 |
| EFHD2 | EF-hand domain family, member D2 | 0.0290883 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0289586 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0279839 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.027617 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0275386 |
| APOL2 | apolipoprotein L, 2 | 0.0273814 |
| PRKCA | protein kinase C, alpha | 0.0270335 |
| MAP1B | microtubule-associated protein 1B | 0.0262628 |
| PHF14 | PHD finger protein 14 | 0.0262265 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0261795 |
| RPS8 | ribosomal protein S8 | 0.0256922 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0255981 |
| VDAC1 | voltage-dependent anion channel 1 | 0.025187 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.025037 |
| SERINC3 | serine incorporator 3 | 0.0248603 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0245789 |
| PFKP | phosphofructokinase, platelet | 0.0245358 |
| GPC6 | glypican 6 | 0.0241666 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0239723 |
| GOLGB1 | golgin B1 | 0.0239275 |
| RPL23 | ribosomal protein L23 | 0.0238179 |
| PTN | pleiotrophin | 0.0236969 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0235662 |
| PARD3 | par-3 family cell polarity regulator | 0.0235383 |
| GOLT1B | golgi transport 1B | 0.0235336 |
| SMTN | smoothelin | 0.0234119 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0233671 |
| MYLK | myosin light chain kinase | 0.0233107 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.023302 |
| RPL3 | ribosomal protein L3 | 0.0229505 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0228086 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0227412 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0225327 |
| TPM2 | tropomyosin 2 (beta) | 0.0224856 |
| PLEC | plectin | 0.0222256 |
| SNW1 | SNW domain containing 1 | 0.0220819 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0220001 |
| COL5A1 | collagen, type V, alpha 1 | 0.021939 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0217896 |
| RPS27 | ribosomal protein S27 | 0.0217613 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.0217523 |
| RPS19 | ribosomal protein S19 | 0.0215911 |
| RNF213 | ring finger protein 213 | 0.0214357 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0212992 |
| LAMB3 | laminin, beta 3 | 0.0212961 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.020858 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0208147 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.020711 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0206763 |
| YTHDC1 | YTH domain containing 1 | 0.0206756 |
| CPAP | centrosome assembly and centriole elongation protein | 0.0206289 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0204875 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0204661 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.0204653 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0204496 |
| ADAR | adenosine deaminase, RNA-specific | 0.0204131 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0203014 |
| PNN | pinin, desmosome associated protein | 0.02024 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0201514 |
| RPL12 | ribosomal protein L12 | 0.0199965 |
| SMAD3 | SMAD family member 3 | 0.0198328 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.319887 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.222675 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.100305 |
| VIM | vimentin | -0.0955477 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0739631 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0691806 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0691678 |
| ATP13A3 | ATPase type 13A3 | -0.0647859 |
| LOX | lysyl oxidase | -0.0644767 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0639059 |
| GOLGA4 | golgin A4 | -0.0635372 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0621186 |
| CALD1 | caldesmon 1 | -0.0581632 |
| GLIS3 | GLIS family zinc finger 3 | -0.0563435 |
| SEPTIN7 | septin 7 | -0.0543258 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0540818 |
| VCL | vinculin | -0.0530694 |
| CANX | calnexin | -0.0519156 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.050679 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0490492 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0480927 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0473259 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0463738 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0461548 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0460003 |
| FN1 | fibronectin 1 | -0.0453797 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0442104 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0439165 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0435427 |
| UBC | ubiquitin C | -0.0427485 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0421216 |
| MEF2A | myocyte enhancer factor 2A | -0.0418561 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0416176 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0415168 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0397421 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0394049 |
| COL1A2 | collagen, type I, alpha 2 | -0.0388608 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.038603 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0380567 |
| NOP58 | NOP58 ribonucleoprotein | -0.0371629 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0366473 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0364488 |
| WASF2 | WAS protein family, member 2 | -0.0363255 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0361691 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0360036 |
| ANKRD12 | ankyrin repeat domain 12 | -0.035856 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0358399 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0344931 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0340314 |
| RTN4 | reticulon 4 | -0.0338861 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0338578 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0338476 |
| MAP4 | microtubule-associated protein 4 | -0.0337251 |
| CD44 | CD44 molecule (Indian blood group) | -0.0334954 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0334704 |
| PRELID2 | PRELI domain containing 2 | -0.0333332 |
| GNAS | GNAS complex locus | -0.0331314 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0330738 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0326726 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0325098 |
| TMEM165 | transmembrane protein 165 | -0.0321697 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0318797 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0318418 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0317954 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.031588 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0312763 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0312593 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0309652 |
| CALU | calumenin | -0.0303123 |
| SEC24D | SEC24 family member D | -0.0303081 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0302582 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0302181 |
| AHNAK | AHNAK nucleoprotein | -0.0302159 |
| S100A10 | S100 calcium binding protein A10 | -0.0296094 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0292506 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0292061 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0289371 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.028831 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0284712 |
| HIP1 | huntingtin interacting protein 1 | -0.0283931 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0283301 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.028311 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.028208 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0281175 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0274811 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0274717 |
| FAM20C | family with sequence similarity 20, member C | -0.0270621 |
| NRXN3 | neurexin 3 | -0.0268589 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0268512 |
| MATR3 | matrin 3 | -0.0268092 |
| HPCAL1 | hippocalcin-like 1 | -0.0267825 |
| RRBP1 | ribosome binding protein 1 | -0.0267245 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0266864 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0266514 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.026604 |
| RUNX1 | runt-related transcription factor 1 | -0.0262806 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0260516 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0259568 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0255911 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0255413 |
