| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.113526 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0858406 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0856018 |
| CEP250 | centrosomal protein 250kDa | 0.0743777 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0723305 |
| TMSB10 | thymosin beta 10 | 0.0720413 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0700695 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.064135 |
| RPL23 | ribosomal protein L23 | 0.0509936 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0505514 |
| PKM | pyruvate kinase, muscle | 0.0505469 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0480819 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0476759 |
| NONO | non-POU domain containing, octamer-binding | 0.0474078 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0469403 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0436823 |
| SEPTIN2 | septin 2 | 0.0436439 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0432731 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0415795 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0408365 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0408129 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0405577 |
| FUS | FUS RNA binding protein | 0.0404503 |
| NDRG1 | N-myc downstream regulated 1 | 0.0383751 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0375698 |
| GPR107 | G protein-coupled receptor 107 | 0.0352133 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0348735 |
| STAG3 | stromal antigen 3 | 0.0346352 |
| MT2A | metallothionein 2A | 0.0345095 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0342271 |
| NBAS | neuroblastoma amplified sequence | 0.034223 |
| SET | SET nuclear proto-oncogene | 0.0341269 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0333723 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0333507 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0331632 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0329389 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0326115 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0320312 |
| RPL35A | ribosomal protein L35a | 0.0316817 |
| INSIG1 | insulin induced gene 1 | 0.03162 |
| HLA-A | major histocompatibility complex, class I, A | 0.0314613 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0312245 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0305265 |
| PARD3 | par-3 family cell polarity regulator | 0.0305251 |
| FMNL2 | formin-like 2 | 0.0303469 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0302838 |
| ARRDC3 | arrestin domain containing 3 | 0.0298362 |
| NUP58 | nucleoporin 58 | 0.0295705 |
| SDC4 | syndecan 4 | 0.029308 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0292198 |
| TPI1 | triosephosphate isomerase 1 | 0.0291382 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0288399 |
| ARF4 | ADP-ribosylation factor 4 | 0.0285937 |
| YBX1 | Y box binding protein 1 | 0.0282644 |
| RNF145 | ring finger protein 145 | 0.0281721 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0281175 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0278521 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0276958 |
| HLA-B | major histocompatibility complex, class I, B | 0.0274474 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.0274312 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0271243 |
| RPLP1 | ribosomal protein, large, P1 | 0.0269766 |
| PER1 | period circadian clock 1 | 0.026791 |
| ZNF292 | zinc finger protein 292 | 0.0265359 |
| NPTN | neuroplastin | 0.0264713 |
| HLA-C | major histocompatibility complex, class I, C | 0.0264007 |
| ERGIC3 | ERGIC and golgi 3 | 0.0263159 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0262915 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0262306 |
| SNX3 | sorting nexin 3 | 0.0260943 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0258949 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0257916 |
| FAM13A | family with sequence similarity 13, member A | 0.0257253 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0256849 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0256211 |
| JUN | jun proto-oncogene | 0.0255945 |
| EGR1 | early growth response 1 | 0.0252875 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0252871 |
| RNF213 | ring finger protein 213 | 0.024923 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0248238 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0245532 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0245281 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0242002 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0240583 |
| RACK1 | receptor for activated C kinase 1 | 0.0238071 |
| RBM33 | RNA binding motif protein 33 | 0.0237285 |
| RPL7A | ribosomal protein L7a | 0.0231828 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.023039 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0229764 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0229457 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0229301 |
| RPL35 | ribosomal protein L35 | 0.022537 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0224991 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0224009 |
| SEC13 | SEC13 homolog (S. cerevisiae) | 0.0223694 |
| PLEC | plectin | 0.0223567 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0222299 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0221687 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.022133 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.021923 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.39944 |
| CD44 | CD44 molecule (Indian blood group) | -0.115491 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0822016 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0658628 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.064953 |
| GOLGA4 | golgin A4 | -0.0577473 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0574623 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0568201 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0562504 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0555638 |
| ATM | ATM serine/threonine kinase | -0.0535919 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0514788 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0493266 |
| SMYD3 | SET and MYND domain containing 3 | -0.0486405 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0485269 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0455791 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0451788 |
| NBEAL1 | neurobeachin-like 1 | -0.0445751 |
| CENPF | centromere protein F, 350/400kDa | -0.0433359 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0409256 |
| GOLGB1 | golgin B1 | -0.0403348 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0398336 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0384754 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0384476 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0374589 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0366711 |
| INTS6 | integrator complex subunit 6 | -0.0366075 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0363414 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0363266 |
| VMP1 | vacuole membrane protein 1 | -0.0360442 |
| METTL15 | methyltransferase like 15 | -0.0359647 |
| HMGA2 | high mobility group AT-hook 2 | -0.0350498 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0350339 |
| RDX | radixin | -0.0340347 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0340286 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0340139 |
| NBEA | neurobeachin | -0.0337068 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0334302 |
| USP34 | ubiquitin specific peptidase 34 | -0.0327143 |
| DST | dystonin | -0.0322686 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0320413 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0319594 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.031803 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0316971 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0312522 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0307264 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.030625 |
| VCL | vinculin | -0.0305926 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0305834 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0301837 |
| NALCN | sodium leak channel, non selective | -0.0299252 |
| GPHN | gephyrin | -0.0298841 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.029364 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0290355 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0289751 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0289624 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0286004 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0284942 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0282442 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0280628 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0279357 |
| FBXO11 | F-box protein 11 | -0.0277938 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0277709 |
| EXOC4 | exocyst complex component 4 | -0.0277556 |
| HDAC9 | histone deacetylase 9 | -0.0275014 |
| TAOK1 | TAO kinase 1 | -0.0272799 |
| RAB10 | RAB10, member RAS oncogene family | -0.0270758 |
| RB1 | retinoblastoma 1 | -0.0269973 |
| BPTF | bromodomain PHD finger transcription factor | -0.026944 |
| SETX | senataxin | -0.0268214 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0267908 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0266488 |
| IGF2 | insulin-like growth factor 2 | -0.0265744 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0264849 |
| OSBPL6 | oxysterol binding protein-like 6 | -0.0263053 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0262424 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0259758 |
| OSMR | oncostatin M receptor | -0.0259623 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0255967 |
| NF1 | neurofibromin 1 | -0.0254365 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0253146 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0253007 |
| PRR11 | proline rich 11 | -0.0252529 |
| CEP57 | centrosomal protein 57kDa | -0.0251963 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0251827 |
| TPX2 | TPX2, microtubule-associated | -0.0251537 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0251257 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0250056 |
| RPS2 | ribosomal protein S2 | -0.0249069 |
| TMEM123 | transmembrane protein 123 | -0.024853 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0245616 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0245389 |
| CCDC88A | coiled-coil domain containing 88A | -0.0244523 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0243073 |
| AK1 | adenylate kinase 1 | -0.0242376 |
| CEP350 | centrosomal protein 350kDa | -0.0241895 |
| NLK | nemo-like kinase | -0.0241485 |
| ATG7 | autophagy related 7 | -0.0241484 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.024062 |
| RIGI | RNA sensor RIG-I | -0.0237607 |
