| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.10221 |
| MT2A | metallothionein 2A | 0.0691618 |
| VEGFA | vascular endothelial growth factor A | 0.0676719 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0572327 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.045378 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0433102 |
| TMSB4X | thymosin beta 4, X-linked | 0.0411727 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0407297 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0404259 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0389797 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0374823 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0359731 |
| SMAD3 | SMAD family member 3 | 0.0339756 |
| PELO | pelota homolog (Drosophila) | 0.0334384 |
| RPL3 | ribosomal protein L3 | 0.0326357 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0318139 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0312542 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0294626 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0286661 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0283083 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0277996 |
| PLEC | plectin | 0.0273208 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0268169 |
| FLNA | filamin A, alpha | 0.0267422 |
| NONO | non-POU domain containing, octamer-binding | 0.0263865 |
| SFTPA2 | surfactant protein A2 | 0.0260635 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.025959 |
| SMOX | spermine oxidase | 0.0249542 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0248579 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0247638 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0245268 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0236643 |
| HLA-C | major histocompatibility complex, class I, C | 0.0235226 |
| NCOR2 | nuclear receptor corepressor 2 | 0.023521 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0234897 |
| TMSB10 | thymosin beta 10 | 0.0226304 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0221657 |
| AFDN | afadin, adherens junction formation factor | 0.0213282 |
| RPL37 | ribosomal protein L37 | 0.0212725 |
| HLA-B | major histocompatibility complex, class I, B | 0.0211743 |
| CEP250 | centrosomal protein 250kDa | 0.0211606 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0211342 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0206674 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0203435 |
| HDGF | hepatoma-derived growth factor | 0.0203159 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0196711 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0195276 |
| FOSL1 | FOS-like antigen 1 | 0.0192493 |
| CPNE1 | copine I | 0.0192357 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0191266 |
| ANGPTL4 | angiopoietin-like 4 | 0.0190645 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0186065 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0184191 |
| SON | SON DNA binding protein | 0.018166 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0179201 |
| HRNR | hornerin | 0.0178852 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0178094 |
| SQSTM1 | sequestosome 1 | 0.0176785 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0176541 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0176521 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0175954 |
| SYNJ2 | synaptojanin 2 | 0.0175939 |
| SDC4 | syndecan 4 | 0.0175779 |
| FOSL2 | FOS-like antigen 2 | 0.0175622 |
| PRELID2 | PRELI domain containing 2 | 0.0175614 |
| MSN | moesin | 0.0175512 |
| SEPTIN2 | septin 2 | 0.0173223 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0171256 |
| NDRG1 | N-myc downstream regulated 1 | 0.0171186 |
| GOLGA2 | golgin A2 | 0.0169397 |
| RPS27 | ribosomal protein S27 | 0.0169249 |
| ACTN1 | actinin, alpha 1 | 0.0166817 |
| INTS1 | integrator complex subunit 1 | 0.01662 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.0164755 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0164069 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.0163552 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.016353 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0162446 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0161611 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0160788 |
| YBX3 | Y box binding protein 3 | 0.0159631 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0158364 |
| MEF2D | myocyte enhancer factor 2D | 0.015789 |
| PNN | pinin, desmosome associated protein | 0.0157422 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0157416 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0155469 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0155305 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0151824 |
| GUK1 | guanylate kinase 1 | 0.0151461 |
| PDCD6 | programmed cell death 6 | 0.0151283 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0151062 |
| HLA-A | major histocompatibility complex, class I, A | 0.0150851 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0150137 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0149133 |
| DBN1 | drebrin 1 | 0.0147705 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0147431 |
| TGM2 | transglutaminase 2 | 0.014587 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0145833 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0144599 |
| CAB39 | calcium binding protein 39 | 0.0143421 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.582652 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.162179 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.153255 |
| FN1 | fibronectin 1 | -0.149244 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.135221 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.130258 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0903001 |
| CANX | calnexin | -0.0788847 |
| NRG1 | neuregulin 1 | -0.0750911 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0748375 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0664155 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0573557 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0519427 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0494523 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0489765 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0471967 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0467346 |
| IER3 | immediate early response 3 | -0.0463245 |
| S100A10 | S100 calcium binding protein A10 | -0.0438793 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0426096 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0412618 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0410076 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0402321 |
| TXNIP | thioredoxin interacting protein | -0.0388581 |
| WAC | WW domain containing adaptor with coiled-coil | -0.038528 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0379714 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0379375 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0362649 |
| VIM | vimentin | -0.0357738 |
| RTN4 | reticulon 4 | -0.0355845 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0350777 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0346912 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0341747 |
| JMJD1C | jumonji domain containing 1C | -0.0338137 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.033302 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0324102 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0319372 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.031733 |
| H1-0 | H1.0 linker histone | -0.0316605 |
| ITGA1 | integrin, alpha 1 | -0.0316517 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0312738 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0307563 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0299966 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0298073 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0294746 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0293327 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0292703 |
| TMEM263 | transmembrane protein 263 | -0.0288941 |
| TMEM156 | transmembrane protein 156 | -0.0287542 |
| QKI | QKI, KH domain containing, RNA binding | -0.0287108 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0286668 |
| GNAS | GNAS complex locus | -0.0279867 |
| HMGA1 | high mobility group AT-hook 1 | -0.0279163 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0277767 |
| SYT1 | synaptotagmin I | -0.0277655 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0276463 |
| HMGA2 | high mobility group AT-hook 2 | -0.0273713 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0268847 |
| NEK7 | NIMA-related kinase 7 | -0.0267392 |
| UBC | ubiquitin C | -0.0263208 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0261735 |
| SEPTIN7 | septin 7 | -0.0261695 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0261291 |
| PARD3 | par-3 family cell polarity regulator | -0.0259736 |
| MAP1B | microtubule-associated protein 1B | -0.025799 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0256789 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0255038 |
| RPS24 | ribosomal protein S24 | -0.0254858 |
| DSTN | destrin (actin depolymerizing factor) | -0.0254572 |
| SPAG9 | sperm associated antigen 9 | -0.0254003 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0252824 |
| FTL | ferritin, light polypeptide | -0.0250897 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0250483 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0249529 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0247912 |
| RPS23 | ribosomal protein S23 | -0.024617 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0246159 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0245874 |
| PTK2 | protein tyrosine kinase 2 | -0.0245122 |
| VCL | vinculin | -0.0241555 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0240598 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0240482 |
| PTMA | prothymosin, alpha | -0.0240138 |
| WASF2 | WAS protein family, member 2 | -0.0235372 |
| RLF | rearranged L-myc fusion | -0.0235313 |
| MTDH | metadherin | -0.0234913 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0234018 |
| DNM1L | dynamin 1-like | -0.0233826 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0231397 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0230095 |
| ASPH | aspartate beta-hydroxylase | -0.0229446 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0229002 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0228479 |
| RPS8 | ribosomal protein S8 | -0.0228255 |
| RASAL2 | RAS protein activator like 2 | -0.0225802 |
| ZNF217 | zinc finger protein 217 | -0.0222182 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.022167 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.022077 |
| TXNRD1 | thioredoxin reductase 1 | -0.022057 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0218491 |
