| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT8 | keratin 8, type II | 0.208679 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.111555 |
| KRT18 | keratin 18, type I | 0.107676 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0862195 |
| PLEC | plectin | 0.0840435 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0821418 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0775675 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.075468 |
| TMSB10 | thymosin beta 10 | 0.0717529 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0584784 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0577226 |
| NONO | non-POU domain containing, octamer-binding | 0.0558671 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0553533 |
| TMSB4X | thymosin beta 4, X-linked | 0.0527604 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0514965 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0514415 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0508984 |
| ANXA11 | annexin A11 | 0.0505635 |
| PTMA | prothymosin, alpha | 0.0498662 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0483535 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.047894 |
| RPL3 | ribosomal protein L3 | 0.0474254 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0472969 |
| PGK1 | phosphoglycerate kinase 1 | 0.0469078 |
| FLNA | filamin A, alpha | 0.0454477 |
| B2M | beta-2-microglobulin | 0.0450305 |
| NDRG1 | N-myc downstream regulated 1 | 0.0445478 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0438314 |
| ACTN4 | actinin, alpha 4 | 0.0437858 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0424655 |
| EZR | ezrin | 0.0421067 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0418467 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0417967 |
| VEGFA | vascular endothelial growth factor A | 0.0398934 |
| FOSL1 | FOS-like antigen 1 | 0.0379029 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0378246 |
| MXD1 | MAX dimerization protein 1 | 0.0360822 |
| MKRN1 | makorin ring finger protein 1 | 0.0360232 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0356929 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0356004 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0351923 |
| MYO5B | myosin VB | 0.0351305 |
| PCBP2 | poly(rC) binding protein 2 | 0.0345756 |
| YBX1 | Y box binding protein 1 | 0.034202 |
| RPL23 | ribosomal protein L23 | 0.0339004 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0330793 |
| TSC22D2 | TSC22 domain family, member 2 | 0.033008 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0328656 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0323915 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0323394 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0322033 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0316106 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0315932 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0311561 |
| DIDO1 | death inducer-obliterator 1 | 0.0309928 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0306651 |
| CEP250 | centrosomal protein 250kDa | 0.0301806 |
| NPTN | neuroplastin | 0.0301622 |
| CXXC5 | CXXC finger protein 5 | 0.0300964 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0299815 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0298331 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0296999 |
| RPS19 | ribosomal protein S19 | 0.0295275 |
| ADM | adrenomedullin | 0.0294204 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0292191 |
| SET | SET nuclear proto-oncogene | 0.029127 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0291215 |
| PKM | pyruvate kinase, muscle | 0.0289526 |
| DSPP | dentin sialophosphoprotein | 0.0281154 |
| AFDN | afadin, adherens junction formation factor | 0.0278303 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0277855 |
| HLA-A | major histocompatibility complex, class I, A | 0.0270233 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0270069 |
| AMOTL2 | angiomotin like 2 | 0.0269902 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0269655 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.026925 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0268758 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0267114 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0266737 |
| MYO10 | myosin X | 0.0265171 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0263269 |
| TPM3 | tropomyosin 3 | 0.0261097 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0260023 |
| HLA-C | major histocompatibility complex, class I, C | 0.0256891 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.025299 |
| SF1 | splicing factor 1 | 0.0252237 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.025156 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0251176 |
| HOXB6 | homeobox B6 | 0.0250974 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0250806 |
| JUN | jun proto-oncogene | 0.0249466 |
| SFTPA2 | surfactant protein A2 | 0.0243947 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0243911 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0242983 |
| PRELID3B | PRELI domain containing 3B | 0.0241811 |
| CST3 | cystatin C | 0.0239817 |
| HYOU1 | hypoxia up-regulated 1 | 0.0239617 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0239504 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0239347 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0238884 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0899501 |
| EHBP1 | EH domain binding protein 1 | -0.0711712 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0678197 |
| NEBL | nebulette | -0.0648998 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0637353 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0626446 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0605378 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.06035 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0602336 |
| CDK13 | cyclin-dependent kinase 13 | -0.0581875 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0552521 |
| JMJD1C | jumonji domain containing 1C | -0.0526355 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0499201 |
| GNAS | GNAS complex locus | -0.0498163 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0459896 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0455134 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0444627 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0432227 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0429071 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0425685 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0420281 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0414985 |
| CCND1 | cyclin D1 | -0.0412785 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0400675 |
| PLSCR1 | phospholipid scramblase 1 | -0.0399813 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.039899 |
| IER3 | immediate early response 3 | -0.0397926 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0395673 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0387701 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0384407 |
| GOLGB1 | golgin B1 | -0.0378764 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0376735 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0374079 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0366886 |
| CADPS | Ca++-dependent secretion activator | -0.0353494 |
| CD2AP | CD2-associated protein | -0.0353392 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0352334 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.035132 |
| GOLGA4 | golgin A4 | -0.0350494 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0346418 |
| MAP4 | microtubule-associated protein 4 | -0.0341806 |
| GPHN | gephyrin | -0.0341554 |
| MYO1E | myosin IE | -0.0340958 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0338518 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0329779 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0325774 |
| NF1 | neurofibromin 1 | -0.0323753 |
| PKP4 | plakophilin 4 | -0.0322369 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0320984 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0319638 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0306608 |
| EXOC4 | exocyst complex component 4 | -0.0306123 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.03035 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0301436 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0299788 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0299085 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0294841 |
| CUX1 | cut-like homeobox 1 | -0.0291078 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0289227 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0286859 |
| ETV6 | ets variant 6 | -0.028506 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0284729 |
| TMEM123 | transmembrane protein 123 | -0.0282634 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0276981 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0274558 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0274345 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0264053 |
| VCL | vinculin | -0.0259591 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0257132 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0256907 |
| CANX | calnexin | -0.0255147 |
| FBXO11 | F-box protein 11 | -0.0254626 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0251758 |
| USP34 | ubiquitin specific peptidase 34 | -0.0246916 |
| HM13 | histocompatibility (minor) 13 | -0.0245876 |
| NFIA | nuclear factor I/A | -0.024317 |
| TCF12 | transcription factor 12 | -0.0241718 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0239965 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0239347 |
| SMAD2 | SMAD family member 2 | -0.0238461 |
| PHF14 | PHD finger protein 14 | -0.0238436 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0234885 |
| NRP1 | neuropilin 1 | -0.023473 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0233591 |
| TOP1 | topoisomerase (DNA) I | -0.02332 |
| MX2 | MX dynamin-like GTPase 2 | -0.0232735 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0232254 |
| GPATCH8 | G patch domain containing 8 | -0.023094 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0230907 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0230376 |
| COG5 | component of oligomeric golgi complex 5 | -0.0229742 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0229186 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0227983 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0226825 |
| SBF2 | SET binding factor 2 | -0.0225844 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0224296 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.022384 |
| RTN3 | reticulon 3 | -0.0222949 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0221088 |
| CDK12 | cyclin-dependent kinase 12 | -0.0219718 |
