| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.169656 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.141763 |
| EZR | ezrin | 0.12226 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.109567 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.107935 |
| RPL3 | ribosomal protein L3 | 0.106147 |
| HSPA8 | heat shock 70kDa protein 8 | 0.100665 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0916504 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.074431 |
| EPHA2 | EPH receptor A2 | 0.0665325 |
| PLAUR | plasminogen activator, urokinase receptor | 0.065038 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0645666 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0595402 |
| CD9 | CD9 molecule | 0.0587885 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0576839 |
| FOSL1 | FOS-like antigen 1 | 0.0549911 |
| ANXA1 | annexin A1 | 0.0538384 |
| EGR1 | early growth response 1 | 0.0537735 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0533456 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.053098 |
| LAMC2 | laminin, gamma 2 | 0.0516634 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0510946 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0498424 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0490885 |
| FERMT1 | fermitin family member 1 | 0.0479082 |
| ANXA11 | annexin A11 | 0.0466073 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0449281 |
| PTMA | prothymosin, alpha | 0.0446558 |
| KRT8 | keratin 8, type II | 0.0437694 |
| NIBAN2 | niban apoptosis regulator 2 | 0.043653 |
| NONO | non-POU domain containing, octamer-binding | 0.0429588 |
| ACTN4 | actinin, alpha 4 | 0.0412547 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0411337 |
| DSPP | dentin sialophosphoprotein | 0.0405296 |
| RPL4 | ribosomal protein L4 | 0.0401701 |
| AREG | amphiregulin | 0.0400925 |
| SET | SET nuclear proto-oncogene | 0.0393446 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.039123 |
| BMP4 | bone morphogenetic protein 4 | 0.0372371 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0372001 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0366736 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0363256 |
| NDRG1 | N-myc downstream regulated 1 | 0.0361637 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0358656 |
| AXIN2 | axin 2 | 0.0353364 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0346098 |
| FAT1 | FAT atypical cadherin 1 | 0.0344293 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0340214 |
| PFKP | phosphofructokinase, platelet | 0.0336516 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0321821 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0320504 |
| PLEC | plectin | 0.032048 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.031709 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0313432 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0306452 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0303282 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.030324 |
| RPS3 | ribosomal protein S3 | 0.0298568 |
| SNX9 | sorting nexin 9 | 0.0295652 |
| HLA-B | major histocompatibility complex, class I, B | 0.0293797 |
| ITGB4 | integrin, beta 4 | 0.0287416 |
| LAMB3 | laminin, beta 3 | 0.0287163 |
| S100A6 | S100 calcium binding protein A6 | 0.028705 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0284927 |
| RPS17 | ribosomal protein S17 | 0.0282907 |
| RPS18 | ribosomal protein S18 | 0.0275848 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0274215 |
| APP | amyloid beta (A4) precursor protein | 0.0272744 |
| LMNA | lamin A/C | 0.0272474 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0270872 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0268611 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0267536 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0266538 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0264827 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0262185 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0260708 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0260038 |
| MYO5B | myosin VB | 0.0257624 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0257243 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0254328 |
| TBCD | tubulin folding cofactor D | 0.0253912 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0253526 |
| RPL37 | ribosomal protein L37 | 0.025065 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0249951 |
| PNN | pinin, desmosome associated protein | 0.0249396 |
| FLNA | filamin A, alpha | 0.0248392 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0246968 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0244058 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.024251 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0241134 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0239673 |
| PCBP2 | poly(rC) binding protein 2 | 0.0239079 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0237713 |
| ACTG1 | actin gamma 1 | 0.0237596 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0237525 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.023685 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0235537 |
| SF1 | splicing factor 1 | 0.023482 |
| TPM4 | tropomyosin 4 | 0.023262 |
| VEGFA | vascular endothelial growth factor A | 0.02321 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.278352 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.202694 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.169253 |
| IER3 | immediate early response 3 | -0.134161 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0896707 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0767241 |
| VCL | vinculin | -0.0646558 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0598741 |
| RPS24 | ribosomal protein S24 | -0.0592717 |
| GPHN | gephyrin | -0.0535873 |
| EGFR | epidermal growth factor receptor | -0.0500131 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0437996 |
| MTAP | methylthioadenosine phosphorylase | -0.0417715 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0401305 |
| FHL2 | four and a half LIM domains 2 | -0.0386266 |
| GOLGA4 | golgin A4 | -0.0383198 |
| GDF15 | growth differentiation factor 15 | -0.0361268 |
| CANX | calnexin | -0.0350441 |
| COG5 | component of oligomeric golgi complex 5 | -0.0350219 |
| CDK13 | cyclin-dependent kinase 13 | -0.0348101 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0321606 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0317791 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.030481 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0292044 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0290759 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0284594 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0281559 |
| RPL34 | ribosomal protein L34 | -0.0277214 |
| TOP1 | topoisomerase (DNA) I | -0.0274641 |
| TNPO1 | transportin 1 | -0.0266747 |
| RAB10 | RAB10, member RAS oncogene family | -0.0266419 |
| RTN3 | reticulon 3 | -0.0265279 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0264271 |
| SEC24D | SEC24 family member D | -0.0263127 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0262773 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0262747 |
| MAP4 | microtubule-associated protein 4 | -0.0260155 |
| RPLP1 | ribosomal protein, large, P1 | -0.0258848 |
| HMGA1 | high mobility group AT-hook 1 | -0.025477 |
| ECT2 | epithelial cell transforming 2 | -0.0245921 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0244911 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0243005 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0239534 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0238558 |
| EXOC6B | exocyst complex component 6B | -0.0238517 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0231269 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0230706 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0229677 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0229073 |
| RPS15 | ribosomal protein S15 | -0.0227741 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0227419 |
| UBC | ubiquitin C | -0.0224534 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0222631 |
| R3HDM1 | R3H domain containing 1 | -0.0219956 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0217804 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0216843 |
| EFNB2 | ephrin-B2 | -0.0216308 |
| HMGB1 | high mobility group box 1 | -0.0215726 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0211404 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0210451 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0209597 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0206868 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0206791 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0203575 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0202757 |
| RBM25 | RNA binding motif protein 25 | -0.020171 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0201542 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.01995 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0196758 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.01955 |
| DSG2 | desmoglein 2 | -0.0194911 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0194407 |
| TAOK1 | TAO kinase 1 | -0.0192389 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0192009 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0190158 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0188456 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0188209 |
| ARF1 | ADP-ribosylation factor 1 | -0.018696 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0186143 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0185897 |
| ZNF431 | zinc finger protein 431 | -0.0185654 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0185308 |
| DIAPH2 | diaphanous-related formin 2 | -0.0184988 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0184506 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0184438 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0184337 |
| DEK | DEK proto-oncogene | -0.018214 |
| EFNA5 | ephrin-A5 | -0.0180969 |
| CD44 | CD44 molecule (Indian blood group) | -0.0180956 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0178628 |
| TCF12 | transcription factor 12 | -0.0177722 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | -0.0177337 |
| GLCCI1 | glucocorticoid induced 1 | -0.0176818 |
| RPS8 | ribosomal protein S8 | -0.0176585 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0176575 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0175471 |
| PCNX4 | pecanex 4 | -0.0174146 |
| KITLG | KIT ligand | -0.0173513 |
| RPS11 | ribosomal protein S11 | -0.0173305 |
| COG6 | component of oligomeric golgi complex 6 | -0.0173002 |
