| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.230342 |
| VIM | vimentin | 0.188647 |
| NDRG1 | N-myc downstream regulated 1 | 0.12532 |
| COL6A3 | collagen, type VI, alpha 3 | 0.121175 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.118362 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.106849 |
| STC1 | stanniocalcin 1 | 0.102933 |
| FAM13A | family with sequence similarity 13, member A | 0.10238 |
| HLA-B | major histocompatibility complex, class I, B | 0.100405 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0927722 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0926896 |
| ADM | adrenomedullin | 0.0839705 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.079123 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0762997 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0726679 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0716648 |
| B2M | beta-2-microglobulin | 0.0710068 |
| VEGFA | vascular endothelial growth factor A | 0.0688973 |
| TMSB10 | thymosin beta 10 | 0.0673096 |
| NAV2 | neuron navigator 2 | 0.0668244 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0625396 |
| DST | dystonin | 0.0610576 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0594261 |
| RPL3 | ribosomal protein L3 | 0.0573367 |
| GOLGA4 | golgin A4 | 0.0572171 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0563642 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0556419 |
| MSN | moesin | 0.0530158 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0528563 |
| TMSB4X | thymosin beta 4, X-linked | 0.0510769 |
| HLA-A | major histocompatibility complex, class I, A | 0.0507042 |
| TNS1 | tensin 1 | 0.0483102 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0475564 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0472267 |
| NBAS | neuroblastoma amplified sequence | 0.0472243 |
| CALU | calumenin | 0.0467091 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.045955 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0458165 |
| MMP12 | matrix metallopeptidase 12 | 0.0441237 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0440269 |
| MYO10 | myosin X | 0.0439987 |
| PCBP2 | poly(rC) binding protein 2 | 0.0435882 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0424356 |
| YBX1 | Y box binding protein 1 | 0.0404256 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0403183 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0402162 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0398161 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0395421 |
| CALR | calreticulin | 0.0392641 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0390858 |
| FLNA | filamin A, alpha | 0.0389809 |
| NAV1 | neuron navigator 1 | 0.0378783 |
| ZNF292 | zinc finger protein 292 | 0.0366633 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0364251 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0363926 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0363629 |
| SPAG9 | sperm associated antigen 9 | 0.035828 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0357103 |
| FOSL1 | FOS-like antigen 1 | 0.0354727 |
| ENO1 | enolase 1, (alpha) | 0.0351633 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0348664 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0343263 |
| SEPTIN9 | septin 9 | 0.0342256 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0338174 |
| MT2A | metallothionein 2A | 0.032665 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0324275 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0322558 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.031725 |
| AXL | AXL receptor tyrosine kinase | 0.0316833 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0316211 |
| SETD5 | SET domain containing 5 | 0.0310502 |
| INSIG1 | insulin induced gene 1 | 0.0309383 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0305058 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0302208 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0299885 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0298899 |
| COPA | coatomer protein complex, subunit alpha | 0.0297653 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0296546 |
| YBX3 | Y box binding protein 3 | 0.0295773 |
| ATP13A3 | ATPase type 13A3 | 0.029486 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0293419 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0292132 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0290997 |
| NUP58 | nucleoporin 58 | 0.0288415 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0284477 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0281468 |
| FMNL2 | formin-like 2 | 0.0281448 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0275535 |
| FNIP1 | folliculin interacting protein 1 | 0.0275346 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0274285 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0273588 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0273075 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.02703 |
| MEIS1 | Meis homeobox 1 | 0.0268309 |
| STC2 | stanniocalcin 2 | 0.026752 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0266171 |
| CDK19 | cyclin-dependent kinase 19 | 0.0265958 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0263175 |
| PRELID2 | PRELI domain containing 2 | 0.0261867 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0261657 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.271898 |
| COL1A1 | collagen, type I, alpha 1 | -0.143431 |
| FN1 | fibronectin 1 | -0.115474 |
| INHBA | inhibin, beta A | -0.110012 |
| EMP1 | epithelial membrane protein 1 | -0.0881535 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0758079 |
| VCL | vinculin | -0.066694 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0615407 |
| CD44 | CD44 molecule (Indian blood group) | -0.0586455 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0554502 |
| RAI14 | retinoic acid induced 14 | -0.0552329 |
| AHNAK | AHNAK nucleoprotein | -0.0534691 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0491768 |
| ASPH | aspartate beta-hydroxylase | -0.0476301 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0457861 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0443689 |
| LOX | lysyl oxidase | -0.0424851 |
| EGFR | epidermal growth factor receptor | -0.0390602 |
| COL5A3 | collagen, type V, alpha 3 | -0.0371532 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0370207 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0365835 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0363027 |
| CCND1 | cyclin D1 | -0.0360819 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0357367 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0355627 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0352027 |
| FRMD4A | FERM domain containing 4A | -0.035068 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0345477 |
| CAVIN1 | caveolae associated protein 1 | -0.0339042 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0338031 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0314589 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0311678 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0311495 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0309471 |
| CCDC102B | coiled-coil domain containing 102B | -0.0304948 |
| OSMR | oncostatin M receptor | -0.0300791 |
| HMGA2 | high mobility group AT-hook 2 | -0.0279907 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0272003 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0249602 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0249264 |
| DIAPH2 | diaphanous-related formin 2 | -0.0243477 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0240942 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0239158 |
| COL3A1 | collagen, type III, alpha 1 | -0.0236692 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0235868 |
| MTAP | methylthioadenosine phosphorylase | -0.0233679 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0231253 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0230043 |
| BPTF | bromodomain PHD finger transcription factor | -0.0223542 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0216131 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0215996 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0215433 |
| IER3 | immediate early response 3 | -0.0211723 |
| MAP4 | microtubule-associated protein 4 | -0.0207501 |
| GLG1 | golgi glycoprotein 1 | -0.0199008 |
| NABP1 | nucleic acid binding protein 1 | -0.0198215 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0197674 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.019517 |
| JAK1 | Janus kinase 1 | -0.0194145 |
| JMJD1C | jumonji domain containing 1C | -0.0193998 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0189565 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0188508 |
| NF1 | neurofibromin 1 | -0.0186229 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0184552 |
| H1-0 | H1.0 linker histone | -0.0180982 |
| ZNF804A | zinc finger protein 804A | -0.0179355 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0179245 |
| TCF12 | transcription factor 12 | -0.0177764 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.0174342 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0174275 |
| FTL | ferritin, light polypeptide | -0.0174101 |
| PLPP3 | phospholipid phosphatase 3 | -0.0172705 |
| IGF2 | insulin-like growth factor 2 | -0.0171814 |
| CPA6 | carboxypeptidase A6 | -0.0171013 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.016856 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.016833 |
| EHBP1 | EH domain binding protein 1 | -0.0167889 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0167419 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0165362 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0163617 |
| PARVA | parvin, alpha | -0.0163503 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0163374 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0160624 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0160181 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0160021 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0159847 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.01569 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0156704 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.015664 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0156606 |
| THBS2 | thrombospondin 2 | -0.0156417 |
| NOTCH3 | notch 3 | -0.0155436 |
| LOXL2 | lysyl oxidase-like 2 | -0.0154476 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0151553 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0149375 |
| NRP1 | neuropilin 1 | -0.0149062 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0148468 |
| ITPRIPL2 | inositol 1,4,5-trisphosphate receptor interacting protein-like 2 | -0.0147856 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0147087 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0146717 |
