| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Furosemide_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.110497 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0979149 |
| AHNAK | AHNAK nucleoprotein | 0.0799368 |
| CD44 | CD44 molecule (Indian blood group) | 0.0794247 |
| PLAT | plasminogen activator, tissue | 0.077201 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0591557 |
| ANXA2 | annexin A2 | 0.055322 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0479611 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0474872 |
| NDRG1 | N-myc downstream regulated 1 | 0.0468643 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0419919 |
| SQSTM1 | sequestosome 1 | 0.0416973 |
| FLNA | filamin A, alpha | 0.0409549 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0405923 |
| FLNB | filamin B, beta | 0.0404465 |
| MT2A | metallothionein 2A | 0.039683 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0381047 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0380098 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0365543 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0353751 |
| THBS2 | thrombospondin 2 | 0.0353719 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0347523 |
| DST | dystonin | 0.0344968 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0344924 |
| HDAC9 | histone deacetylase 9 | 0.0336416 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.033084 |
| HLA-C | major histocompatibility complex, class I, C | 0.0329664 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0323392 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0321514 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0316863 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0303963 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0303315 |
| B2M | beta-2-microglobulin | 0.029434 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0293198 |
| ENO1 | enolase 1, (alpha) | 0.0291672 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0284378 |
| RTN4 | reticulon 4 | 0.0281854 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.027723 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0264341 |
| TPM3 | tropomyosin 3 | 0.0260944 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0259564 |
| TMSB4X | thymosin beta 4, X-linked | 0.0259547 |
| OGA | O-GlcNAcase | 0.0258772 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0257853 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0257681 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.025416 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0253144 |
| ASPH | aspartate beta-hydroxylase | 0.0250635 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0243208 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0240304 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0238231 |
| VEGFA | vascular endothelial growth factor A | 0.0237676 |
| KLF6 | Kruppel-like factor 6 | 0.023242 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0224009 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0220387 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0219844 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0217599 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0216852 |
| PRELID2 | PRELI domain containing 2 | 0.0209571 |
| NAV2 | neuron navigator 2 | 0.0207862 |
| STC1 | stanniocalcin 1 | 0.0207451 |
| CSTB | cystatin B (stefin B) | 0.0206799 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0206793 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0206569 |
| SEPTIN7 | septin 7 | 0.0206285 |
| HLA-B | major histocompatibility complex, class I, B | 0.0202873 |
| HELZ | helicase with zinc finger | 0.0201719 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0201345 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0198705 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.01976 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0195548 |
| ANLN | anillin, actin binding protein | 0.0193991 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0190801 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0187393 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0186089 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0184873 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0184204 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0180754 |
| CTSB | cathepsin B | 0.0179573 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0177302 |
| ADAR | adenosine deaminase, RNA-specific | 0.017703 |
| PLEC | plectin | 0.0175275 |
| CENPF | centromere protein F, 350/400kDa | 0.0174895 |
| ARRDC3 | arrestin domain containing 3 | 0.0173579 |
| HLA-A | major histocompatibility complex, class I, A | 0.0173268 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0173198 |
| DSG2 | desmoglein 2 | 0.0172687 |
| FNIP1 | folliculin interacting protein 1 | 0.017188 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0169557 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0169422 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0168424 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0168277 |
| NAV1 | neuron navigator 1 | 0.0167073 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0164035 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0163484 |
| POTEF | POTE ankyrin domain family, member F | 0.0161669 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0160958 |
| MYOF | myoferlin | 0.0159194 |
| GOLGA4 | golgin A4 | 0.0157881 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0155777 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.247279 |
| TMSB10 | thymosin beta 10 | -0.197589 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.119841 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0795389 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0539955 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0453692 |
| FN1 | fibronectin 1 | -0.0451393 |
| SUCNR1 | succinate receptor 1 | -0.0445927 |
| COL5A2 | collagen, type V, alpha 2 | -0.040106 |
| COL1A2 | collagen, type I, alpha 2 | -0.0399389 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0350933 |
| TPM1 | tropomyosin 1 (alpha) | -0.0345076 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0336257 |
| CUX1 | cut-like homeobox 1 | -0.0315934 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0307132 |
| FBN1 | fibrillin 1 | -0.0306022 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0263922 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.026222 |
| FTL | ferritin, light polypeptide | -0.0243872 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0235343 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0233471 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0230606 |
| MEIS2 | Meis homeobox 2 | -0.0227645 |
| S100A6 | S100 calcium binding protein A6 | -0.0221053 |
| LMNA | lamin A/C | -0.0217308 |
| TNS3 | tensin 3 | -0.0216659 |
| MX2 | MX dynamin-like GTPase 2 | -0.0216326 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0207582 |
| TENM3 | teneurin transmembrane protein 3 | -0.020569 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0205688 |
| S100A10 | S100 calcium binding protein A10 | -0.0205209 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0205153 |
| AUTS2 | autism susceptibility candidate 2 | -0.017891 |
| TAPBP | TAP binding protein (tapasin) | -0.017027 |
| KRT81 | keratin 81, type II | -0.0166986 |
| LOX | lysyl oxidase | -0.0164238 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0164222 |
| JAZF1 | JAZF zinc finger 1 | -0.0163495 |
| MSI2 | musashi RNA-binding protein 2 | -0.0160997 |
| FRMD4A | FERM domain containing 4A | -0.015933 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0156732 |
| INSIG1 | insulin induced gene 1 | -0.0156428 |
| NPR2 | natriuretic peptide receptor 2 | -0.014874 |
| RPLP1 | ribosomal protein, large, P1 | -0.0148153 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0145944 |
| BSG | basigin (Ok blood group) | -0.0143781 |
| PCDH7 | protocadherin 7 | -0.0143534 |
| TAGLN2 | transgelin 2 | -0.0140968 |
| RIGI | RNA sensor RIG-I | -0.0138692 |
| SRPK2 | SRSF protein kinase 2 | -0.0134625 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0133892 |
| S100A4 | S100 calcium binding protein A4 | -0.0133065 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0129979 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0128742 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0127558 |
| EFNA5 | ephrin-A5 | -0.0126145 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0125931 |
| PKM | pyruvate kinase, muscle | -0.0125787 |
| HOXD10 | homeobox D10 | -0.0125715 |
| PTMA | prothymosin, alpha | -0.0122085 |
| TUBB | tubulin, beta class I | -0.0117985 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0117767 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0117165 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0116062 |
| TOX | thymocyte selection-associated high mobility group box | -0.0114734 |
| COL1A1 | collagen, type I, alpha 1 | -0.0112297 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0111243 |
| FGF13 | fibroblast growth factor 13 | -0.0109721 |
| PRRX1 | paired related homeobox 1 | -0.010774 |
| CCM2 | cerebral cavernous malformation 2 | -0.0107659 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0105342 |
| FADS2 | fatty acid desaturase 2 | -0.0103787 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.0103704 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0102227 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0102091 |
| SP100 | SP100 nuclear antigen | -0.0100826 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0100012 |
| VEGFC | vascular endothelial growth factor C | -0.00998644 |
| GDF15 | growth differentiation factor 15 | -0.0098691 |
| CBX3 | chromobox homolog 3 | -0.00979568 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.00967153 |
| IL7R | interleukin 7 receptor | -0.00919056 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00915212 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0091466 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00907961 |
| COL5A1 | collagen, type V, alpha 1 | -0.00902718 |
| PRSS23 | protease, serine, 23 | -0.00896769 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.00894616 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.00886163 |
| LAP3 | leucine aminopeptidase 3 | -0.00885168 |
| IL32 | interleukin 32 | -0.00880889 |
| ZNF609 | zinc finger protein 609 | -0.00873452 |
| MAP4 | microtubule-associated protein 4 | -0.00867625 |
| TAOK1 | TAO kinase 1 | -0.00865646 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00859214 |
| TMEM165 | transmembrane protein 165 | -0.00854795 |
| ECM1 | extracellular matrix protein 1 | -0.00837647 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00834972 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00828886 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00827324 |
