| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Furosemide_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMC5 | transmembrane channel-like 5 | 0.077665 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0697523 |
| TSC22D1 | TSC22 domain family, member 1 | 0.068512 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0576754 |
| PHF3 | PHD finger protein 3 | 0.057546 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0542499 |
| SPATA13 | spermatogenesis associated 13 | 0.0527262 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0515546 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0476173 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0458113 |
| RAB7A | RAB7A, member RAS oncogene family | 0.042835 |
| LYZ | lysozyme | 0.0424913 |
| TJP1 | tight junction protein 1 | 0.0419683 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0419642 |
| GOLGB1 | golgin B1 | 0.0404532 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0390568 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0388855 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0369926 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0369558 |
| ANXA2 | annexin A2 | 0.0362734 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0357377 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0357225 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0354476 |
| B2M | beta-2-microglobulin | 0.0352535 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0352263 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0347519 |
| ITGA6 | integrin, alpha 6 | 0.0347245 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0341671 |
| EZR | ezrin | 0.0339081 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0328381 |
| AHI1 | Abelson helper integration site 1 | 0.0325411 |
| MAP7 | microtubule-associated protein 7 | 0.0324509 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.03182 |
| LMO7 | LIM domain 7 | 0.0312896 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.031287 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0308701 |
| MYO1E | myosin IE | 0.0303332 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0297456 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0296625 |
| RAD51B | RAD51 paralog B | 0.0293182 |
| MX2 | MX dynamin-like GTPase 2 | 0.0292338 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0292182 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0290224 |
| SSH2 | slingshot protein phosphatase 2 | 0.028861 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0286502 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0285059 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0282197 |
| ATP11A | ATPase, class VI, type 11A | 0.0277722 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0277016 |
| SQSTM1 | sequestosome 1 | 0.0275164 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0275041 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0274896 |
| NPSR1 | neuropeptide S receptor 1 | 0.0274784 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0272584 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0271696 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0268742 |
| MCU | mitochondrial calcium uniporter | 0.0257646 |
| SDC4 | syndecan 4 | 0.0251267 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0246629 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0245737 |
| SPAG9 | sperm associated antigen 9 | 0.023907 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0237681 |
| MLPH | melanophilin | 0.0236124 |
| TPM3 | tropomyosin 3 | 0.0235694 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0233638 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0233256 |
| HLA-E | major histocompatibility complex, class I, E | 0.0232446 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0229057 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0228522 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0227696 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0227256 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0225697 |
| ERBIN | erbb2 interacting protein | 0.0224944 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.0224717 |
| MX1 | MX dynamin-like GTPase 1 | 0.022429 |
| RBM47 | RNA binding motif protein 47 | 0.0222879 |
| VEGFA | vascular endothelial growth factor A | 0.0221395 |
| DIAPH1 | diaphanous-related formin 1 | 0.0219554 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0217647 |
| MUC20 | mucin 20, cell surface associated | 0.0210931 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0210737 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0210714 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0205681 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0205574 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0203296 |
| USP54 | ubiquitin specific peptidase 54 | 0.0202803 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0202315 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0201896 |
| POU2F2 | POU class 2 homeobox 2 | 0.0197401 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0197248 |
| JAK1 | Janus kinase 1 | 0.0196225 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0195369 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0194953 |
| CDK12 | cyclin-dependent kinase 12 | 0.0194454 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0192664 |
| AREG | amphiregulin | 0.0191311 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0188125 |
| JMJD1C | jumonji domain containing 1C | 0.0187293 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.018687 |
| F11R | F11 receptor | 0.018562 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0496192 |
| RNF43 | ring finger protein 43 | -0.0474338 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0444176 |
| RUNX1 | runt-related transcription factor 1 | -0.0437658 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0377131 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.034267 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0321444 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0312015 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0281393 |
| DIAPH3 | diaphanous-related formin 3 | -0.0276939 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0263817 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0259771 |
| MKI67 | marker of proliferation Ki-67 | -0.0253003 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0251475 |
| INTS6 | integrator complex subunit 6 | -0.0242537 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.023244 |
| EFNB2 | ephrin-B2 | -0.0216904 |
| RPL35A | ribosomal protein L35a | -0.0210478 |
| CENPF | centromere protein F, 350/400kDa | -0.0210161 |
| RPLP1 | ribosomal protein, large, P1 | -0.0196387 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0192182 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0191636 |
| TXNIP | thioredoxin interacting protein | -0.0188384 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0187192 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | -0.0182347 |
| TMSB10 | thymosin beta 10 | -0.0181209 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0178735 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.01768 |
| NDRG1 | N-myc downstream regulated 1 | -0.0176653 |
| EHF | ets homologous factor | -0.0172391 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0171231 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0169351 |
| TBPL1 | TBP-like 1 | -0.0169303 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0167318 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0165673 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.016466 |
| LURAP1L | leucine rich adaptor protein 1-like | -0.0164096 |
| TNNC1 | troponin C type 1 (slow) | -0.0162739 |
| RPS24 | ribosomal protein S24 | -0.0161934 |
| SMC4 | structural maintenance of chromosomes 4 | -0.016002 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0157897 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0156021 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.015299 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0149964 |
| RPS6 | ribosomal protein S6 | -0.0146072 |
| DUSP16 | dual specificity phosphatase 16 | -0.0145877 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0142139 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.014173 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0141694 |
| NCKAP5 | NCK-associated protein 5 | -0.0140093 |
| IFNGR1 | interferon gamma receptor 1 | -0.0140004 |
| H1-0 | H1.0 linker histone | -0.0139418 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | -0.013909 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0138502 |
| CD164 | CD164 molecule, sialomucin | -0.0137472 |
| ANLN | anillin, actin binding protein | -0.0136122 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0133285 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0131985 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0131233 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0130735 |
| RPS21 | ribosomal protein S21 | -0.0130686 |
| CERS6 | ceramide synthase 6 | -0.0129121 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0128906 |
| FANCI | Fanconi anemia, complementation group I | -0.0128856 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0128551 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0127425 |
| RBM39 | RNA binding motif protein 39 | -0.0125215 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0124824 |
| GNAS | GNAS complex locus | -0.012275 |
| MLEC | malectin | -0.0122498 |
| SMAD3 | SMAD family member 3 | -0.0120878 |
| PTEN | phosphatase and tensin homolog | -0.0120516 |
| HMGB2 | high mobility group box 2 | -0.0120067 |
| GRAMD2B | GRAM domain containing 2B | -0.0118879 |
| PER3 | period circadian clock 3 | -0.01188 |
| ABLIM1 | actin binding LIM protein 1 | -0.0118705 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0118539 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0118087 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.011716 |
| CLTC | clathrin, heavy chain (Hc) | -0.0116293 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -0.0115543 |
| RPL30 | ribosomal protein L30 | -0.0112208 |
| USP12 | ubiquitin specific peptidase 12 | -0.0111185 |
| RPL9 | ribosomal protein L9 | -0.0110557 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0110513 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.011032 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0109673 |
| SGO2 | shugoshin 2 | -0.0107912 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0107148 |
| GPX2 | glutathione peroxidase 2 | -0.0107011 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0106193 |
| TPI1 | triosephosphate isomerase 1 | -0.0105445 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0105384 |
| FNIP2 | folliculin interacting protein 2 | -0.0104968 |
| TUBB4B | tubulin, beta 4B class IVb | -0.010454 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0103885 |
| ITM2B | integral membrane protein 2B | -0.0103596 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0102764 |
| TUFT1 | tuftelin 1 | -0.0101317 |
| LDHA | lactate dehydrogenase A | -0.0101015 |
