| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Furosemide_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.180992 |
| NDRG1 | N-myc downstream regulated 1 | 0.163478 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.116729 |
| VEGFA | vascular endothelial growth factor A | 0.108367 |
| CD44 | CD44 molecule (Indian blood group) | 0.0858266 |
| COL6A3 | collagen, type VI, alpha 3 | 0.084569 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0667249 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.06335 |
| ENO1 | enolase 1, (alpha) | 0.0498296 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0485426 |
| STC1 | stanniocalcin 1 | 0.0461178 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0451405 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0428438 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0370581 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0347371 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0341288 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0330004 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0318824 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0317717 |
| HLA-A | major histocompatibility complex, class I, A | 0.0308578 |
| CADM1 | cell adhesion molecule 1 | 0.0286883 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0281168 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0270465 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0266348 |
| RPS3 | ribosomal protein S3 | 0.0263541 |
| CALU | calumenin | 0.0262731 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0261027 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.026059 |
| SQSTM1 | sequestosome 1 | 0.025783 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0254754 |
| ARRDC3 | arrestin domain containing 3 | 0.0250985 |
| LOXL2 | lysyl oxidase-like 2 | 0.0246934 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0238168 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0229554 |
| FAT1 | FAT atypical cadherin 1 | 0.0215656 |
| LOX | lysyl oxidase | 0.0212518 |
| POSTN | periostin, osteoblast specific factor | 0.0211564 |
| RPS8 | ribosomal protein S8 | 0.0209523 |
| ATP13A3 | ATPase type 13A3 | 0.0207242 |
| ANXA2 | annexin A2 | 0.0202812 |
| RUNX1 | runt-related transcription factor 1 | 0.0198616 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0195509 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0194811 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0192135 |
| PDE10A | phosphodiesterase 10A | 0.0191142 |
| AHNAK | AHNAK nucleoprotein | 0.0189903 |
| TMSB4X | thymosin beta 4, X-linked | 0.0188537 |
| FLNA | filamin A, alpha | 0.0182997 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0180989 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0180085 |
| SMAD3 | SMAD family member 3 | 0.0179238 |
| SPAG9 | sperm associated antigen 9 | 0.0176953 |
| RPN1 | ribophorin I | 0.0176228 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0172469 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0170723 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.017054 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.016827 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0167805 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0166462 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.016541 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0165016 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0161021 |
| YBX1 | Y box binding protein 1 | 0.0159613 |
| DUSP6 | dual specificity phosphatase 6 | 0.0156687 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0156632 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0155703 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0155164 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0153157 |
| APP | amyloid beta (A4) precursor protein | 0.0153008 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0150512 |
| H1-0 | H1.0 linker histone | 0.0149302 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.014919 |
| RPS12 | ribosomal protein S12 | 0.0147893 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0147629 |
| ZNF292 | zinc finger protein 292 | 0.0146912 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0145757 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0145271 |
| BRD4 | bromodomain containing 4 | 0.0145228 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.014397 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0143905 |
| TPM3 | tropomyosin 3 | 0.01435 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0141768 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0141275 |
| CALR | calreticulin | 0.0139032 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.013736 |
| RPS2 | ribosomal protein S2 | 0.0136838 |
| TMF1 | TATA element modulatory factor 1 | 0.0134695 |
| ACTG1 | actin gamma 1 | 0.0133738 |
| CTSB | cathepsin B | 0.0133099 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0133012 |
| RACK1 | receptor for activated C kinase 1 | 0.0132755 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0131734 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.013132 |
| JUN | jun proto-oncogene | 0.0130364 |
| HLA-B | major histocompatibility complex, class I, B | 0.0130088 |
| QKI | QKI, KH domain containing, RNA binding | 0.0127826 |
| MLF1 | myeloid leukemia factor 1 | 0.0127195 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0126879 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0125035 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0124257 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.222224 |
| TMSB10 | thymosin beta 10 | -0.177699 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0577924 |
| FTL | ferritin, light polypeptide | -0.0574797 |
| TPM4 | tropomyosin 4 | -0.0539774 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0465923 |
| PTMA | prothymosin, alpha | -0.0389556 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0382955 |
| CDH13 | cadherin 13 | -0.0363122 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0349386 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0346904 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0343279 |
| VCL | vinculin | -0.0322342 |
| RPS6 | ribosomal protein S6 | -0.0308777 |
| VCAN | versican | -0.0307784 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0288001 |
| RPLP1 | ribosomal protein, large, P1 | -0.0274257 |
| COL1A2 | collagen, type I, alpha 2 | -0.0272967 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.025859 |
| FBN1 | fibrillin 1 | -0.0232526 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0217709 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0215499 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0215462 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.020941 |
| RRBP1 | ribosome binding protein 1 | -0.0208156 |
| CALD1 | caldesmon 1 | -0.0207551 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0205384 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0203001 |
| TPM1 | tropomyosin 1 (alpha) | -0.0198656 |
| CLIC4 | chloride intracellular channel 4 | -0.0191306 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0189513 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0184842 |
| S100A6 | S100 calcium binding protein A6 | -0.0184819 |
| RPS19 | ribosomal protein S19 | -0.0184315 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0182692 |
| TENM3 | teneurin transmembrane protein 3 | -0.0181617 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0178456 |
| TPM2 | tropomyosin 2 (beta) | -0.0177839 |
| IL6ST | interleukin 6 signal transducer | -0.0175407 |
| FOXP1 | forkhead box P1 | -0.0172516 |
| S100A9 | S100 calcium binding protein A9 | -0.0169053 |
| GLIS3 | GLIS family zinc finger 3 | -0.0164544 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0163315 |
| RPL31 | ribosomal protein L31 | -0.016254 |
| CST3 | cystatin C | -0.0156311 |
| NREP | neuronal regeneration related protein | -0.0154942 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0153496 |
| CLMP | CXADR-like membrane protein | -0.0152874 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.01516 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0150319 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0149182 |
| SULF1 | sulfatase 1 | -0.0147531 |
| RPS5 | ribosomal protein S5 | -0.0143271 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0143267 |
| RPL32 | ribosomal protein L32 | -0.0142507 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.014238 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0142251 |
| FRMD4A | FERM domain containing 4A | -0.0141166 |
| COL1A1 | collagen, type I, alpha 1 | -0.0141025 |
| EBF1 | early B-cell factor 1 | -0.0139041 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0138758 |
| PALLD | palladin, cytoskeletal associated protein | -0.0138289 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0137887 |
| PRKCA | protein kinase C, alpha | -0.0137755 |
| HMGA2 | high mobility group AT-hook 2 | -0.0135858 |
| MAP4 | microtubule-associated protein 4 | -0.0131067 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.013091 |
| VMP1 | vacuole membrane protein 1 | -0.0128997 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0128967 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0128479 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.012802 |
| MYDGF | myeloid-derived growth factor | -0.0126795 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0126479 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0126426 |
| LMO4 | LIM domain only 4 | -0.0124569 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0124502 |
| PRELID2 | PRELI domain containing 2 | -0.0119 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0117832 |
| DGKI | diacylglycerol kinase, iota | -0.0117696 |
| SERINC3 | serine incorporator 3 | -0.0117004 |
| RPL8 | ribosomal protein L8 | -0.0116354 |
| LMNA | lamin A/C | -0.0116223 |
| IER3 | immediate early response 3 | -0.011389 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0113489 |
| PKM | pyruvate kinase, muscle | -0.0112559 |
| ATM | ATM serine/threonine kinase | -0.0110684 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0110486 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0109842 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0108857 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0107788 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0105163 |
| RPS20 | ribosomal protein S20 | -0.0104943 |
| EGR1 | early growth response 1 | -0.0104289 |
| TUBB | tubulin, beta class I | -0.010191 |
| TRAM1 | translocation associated membrane protein 1 | -0.0101774 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0101331 |
| DSTN | destrin (actin depolymerizing factor) | -0.0101219 |
| CUX1 | cut-like homeobox 1 | -0.0100596 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00988265 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0098728 |
