| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Furosemide_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0821069 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0666034 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0628822 |
| CD44 | CD44 molecule (Indian blood group) | 0.0605927 |
| CLU | clusterin | 0.0593229 |
| MEF2A | myocyte enhancer factor 2A | 0.0583643 |
| ANXA2 | annexin A2 | 0.0489462 |
| TMSB4X | thymosin beta 4, X-linked | 0.0476932 |
| MYOF | myoferlin | 0.0472252 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0463254 |
| AHNAK | AHNAK nucleoprotein | 0.0461808 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0441636 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0426593 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0420027 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0390393 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0384918 |
| ENO1 | enolase 1, (alpha) | 0.0372466 |
| KIAA1217 | KIAA1217 | 0.0366083 |
| EMP1 | epithelial membrane protein 1 | 0.0352952 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0348854 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0343515 |
| ARRDC3 | arrestin domain containing 3 | 0.0340509 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.032114 |
| SMAD3 | SMAD family member 3 | 0.0316202 |
| H1-0 | H1.0 linker histone | 0.0303875 |
| CUL4B | cullin 4B | 0.0299985 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0296663 |
| HLA-A | major histocompatibility complex, class I, A | 0.0281256 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0274833 |
| EZR | ezrin | 0.0273105 |
| FOXO1 | forkhead box O1 | 0.0271957 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.02662 |
| TXNIP | thioredoxin interacting protein | 0.0260668 |
| ZNF292 | zinc finger protein 292 | 0.0260647 |
| TGM2 | transglutaminase 2 | 0.0259041 |
| YBX3 | Y box binding protein 3 | 0.0258118 |
| OSMR | oncostatin M receptor | 0.0255266 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.024346 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0239954 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.023874 |
| TPM3 | tropomyosin 3 | 0.0233321 |
| RIN2 | Ras and Rab interactor 2 | 0.0233118 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0225791 |
| HLA-C | major histocompatibility complex, class I, C | 0.0225353 |
| PRELID2 | PRELI domain containing 2 | 0.0224912 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0220105 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0217594 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0215094 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0209132 |
| ASPH | aspartate beta-hydroxylase | 0.0208968 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0208165 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0207541 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0207489 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0200988 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0197472 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0194406 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.01935 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0190504 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0189413 |
| HLA-B | major histocompatibility complex, class I, B | 0.0187481 |
| AFAP1 | actin filament associated protein 1 | 0.0187065 |
| PLAT | plasminogen activator, tissue | 0.0181843 |
| AOPEP | aminopeptidase O (putative) | 0.0180877 |
| PLEC | plectin | 0.017966 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0179305 |
| ANGPTL4 | angiopoietin-like 4 | 0.017901 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0178541 |
| DUSP6 | dual specificity phosphatase 6 | 0.017827 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0176648 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0173034 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.017215 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0170873 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0168489 |
| IGF2 | insulin-like growth factor 2 | 0.0168383 |
| SLK | STE20-like kinase | 0.0167112 |
| SYNJ2 | synaptojanin 2 | 0.0164936 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0163901 |
| ANXA11 | annexin A11 | 0.0163276 |
| RPS3 | ribosomal protein S3 | 0.0162812 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0162713 |
| MTSS1 | metastasis suppressor 1 | 0.0161987 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0161867 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.016131 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.016128 |
| EPHA2 | EPH receptor A2 | 0.0160927 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0160012 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.015971 |
| SLTM | SAFB-like, transcription modulator | 0.0158506 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0157978 |
| BCL2L1 | BCL2-like 1 | 0.0157658 |
| RIOK3 | RIO kinase 3 | 0.0156788 |
| GBP4 | guanylate binding protein 4 | 0.015653 |
| PODXL | podocalyxin-like | 0.015437 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0152743 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0152143 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.015159 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0150863 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0150727 |
| FNIP1 | folliculin interacting protein 1 | 0.0150133 |
| PHF21A | PHD finger protein 21A | 0.0149024 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.103175 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0837548 |
| TMSB10 | thymosin beta 10 | -0.0769707 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0642244 |
| PTMA | prothymosin, alpha | -0.0613739 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0567301 |
| INTS6 | integrator complex subunit 6 | -0.0556621 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0537763 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0510686 |
| POTEF | POTE ankyrin domain family, member F | -0.050093 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0486361 |
| PLS3 | plastin 3 | -0.0429392 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0429267 |
| RPS6 | ribosomal protein S6 | -0.0407648 |
| PALLD | palladin, cytoskeletal associated protein | -0.0398182 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.038443 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0377133 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0375249 |
| LDHA | lactate dehydrogenase A | -0.0374676 |
| RPLP1 | ribosomal protein, large, P1 | -0.0358728 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0355355 |
| UTRN | utrophin | -0.034568 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0332386 |
| FTL | ferritin, light polypeptide | -0.0328851 |
| ITGA6 | integrin, alpha 6 | -0.0319448 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0302751 |
| CDK6 | cyclin-dependent kinase 6 | -0.0295352 |
| DGKH | diacylglycerol kinase, eta | -0.0293692 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0292976 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0292116 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0290141 |
| RPS25 | ribosomal protein S25 | -0.0288595 |
| FLNB | filamin B, beta | -0.0280814 |
| TPM4 | tropomyosin 4 | -0.0272473 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0267849 |
| HMGA2 | high mobility group AT-hook 2 | -0.0258947 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0257008 |
| RPS23 | ribosomal protein S23 | -0.0252164 |
| RPL31 | ribosomal protein L31 | -0.0251264 |
| PKM | pyruvate kinase, muscle | -0.0248402 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0244737 |
| KRT17 | keratin 17, type I | -0.0237315 |
| S100A10 | S100 calcium binding protein A10 | -0.0229609 |
| RASAL2 | RAS protein activator like 2 | -0.0229486 |
| SULF2 | sulfatase 2 | -0.0228551 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0223272 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0219021 |
| WASF2 | WAS protein family, member 2 | -0.0212755 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0210412 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0208116 |
| RPS24 | ribosomal protein S24 | -0.0202932 |
| RPL11 | ribosomal protein L11 | -0.0199438 |
| RPS29 | ribosomal protein S29 | -0.0197674 |
| RCOR1 | REST corepressor 1 | -0.0197084 |
| SULF1 | sulfatase 1 | -0.0196535 |
| S100A2 | S100 calcium binding protein A2 | -0.0196218 |
| PRSS23 | protease, serine, 23 | -0.0194462 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0193719 |
| RPLP2 | ribosomal protein, large, P2 | -0.0193228 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.019197 |
| RPL23 | ribosomal protein L23 | -0.0189006 |
| HMGA1 | high mobility group AT-hook 1 | -0.0188834 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0187982 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0185949 |
| HM13 | histocompatibility (minor) 13 | -0.0184908 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0184492 |
| C4BPB | complement component 4 binding protein, beta | -0.0177791 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0177664 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0176839 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0176078 |
| KIAA1671 | KIAA1671 | -0.0175282 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0174367 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0173199 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0172873 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0172296 |
| EGFR | epidermal growth factor receptor | -0.0171194 |
| NCKAP5 | NCK-associated protein 5 | -0.0171017 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.01703 |
| RPS13 | ribosomal protein S13 | -0.0169596 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0168715 |
| RAB2A | RAB2A, member RAS oncogene family | -0.016871 |
| EFHD2 | EF-hand domain family, member D2 | -0.016317 |
| RPL34 | ribosomal protein L34 | -0.0163014 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.016265 |
| GUK1 | guanylate kinase 1 | -0.0162642 |
| S100A11 | S100 calcium binding protein A11 | -0.0159281 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0158817 |
| TAGLN2 | transgelin 2 | -0.0158091 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0157034 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0155618 |
| PDS5B | PDS5 cohesin associated factor B | -0.0155199 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0155094 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0155044 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.015472 |
| FRMD6 | FERM domain containing 6 | -0.0154037 |
| FBXO11 | F-box protein 11 | -0.0150932 |
| RPS14 | ribosomal protein S14 | -0.0150216 |
| RPS17 | ribosomal protein S17 | -0.0148357 |
| GNAS | GNAS complex locus | -0.0148017 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.014767 |