| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Furosemide_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.154296 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0978325 |
| AHNAK | AHNAK nucleoprotein | 0.0895639 |
| VEGFA | vascular endothelial growth factor A | 0.0739265 |
| FAT1 | FAT atypical cadherin 1 | 0.0730299 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0660914 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0648201 |
| NDRG1 | N-myc downstream regulated 1 | 0.0645447 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0638295 |
| ONECUT3 | one cut homeobox 3 | 0.0596179 |
| RPS8 | ribosomal protein S8 | 0.0594067 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0585833 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0551121 |
| TXNIP | thioredoxin interacting protein | 0.0541579 |
| EZR | ezrin | 0.0526636 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.05211 |
| ENO1 | enolase 1, (alpha) | 0.0504531 |
| RPS12 | ribosomal protein S12 | 0.0482444 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0467181 |
| DSPP | dentin sialophosphoprotein | 0.0454598 |
| CANX | calnexin | 0.0452444 |
| H1-0 | H1.0 linker histone | 0.0427119 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0393758 |
| DSG2 | desmoglein 2 | 0.039258 |
| GOLGA4 | golgin A4 | 0.0392284 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0390822 |
| CALR | calreticulin | 0.0389638 |
| NEBL | nebulette | 0.0387667 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0369125 |
| ATXN1 | ataxin 1 | 0.0369043 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0367713 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0365705 |
| FAM13A | family with sequence similarity 13, member A | 0.0359047 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0351407 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0346968 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0335856 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0331031 |
| MUC13 | mucin 13, cell surface associated | 0.0330003 |
| ZNF292 | zinc finger protein 292 | 0.0323629 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0317677 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0308606 |
| MT2A | metallothionein 2A | 0.030338 |
| TMSB4X | thymosin beta 4, X-linked | 0.0288725 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0285912 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0284003 |
| RPS3 | ribosomal protein S3 | 0.0273428 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0266773 |
| RPS27A | ribosomal protein S27a | 0.0266348 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0262678 |
| ANXA2 | annexin A2 | 0.0259029 |
| RPL26 | ribosomal protein L26 | 0.0258428 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0257861 |
| RPL13A | ribosomal protein L13a | 0.0249825 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0249554 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0248778 |
| GOLGB1 | golgin B1 | 0.0247924 |
| RPS6 | ribosomal protein S6 | 0.0244919 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0244108 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0243745 |
| ANXA1 | annexin A1 | 0.0243378 |
| LMO7 | LIM domain 7 | 0.0240728 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0240713 |
| B2M | beta-2-microglobulin | 0.0239653 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0234752 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0234449 |
| KLF6 | Kruppel-like factor 6 | 0.0232619 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0223485 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0223203 |
| SQSTM1 | sequestosome 1 | 0.0217535 |
| AFDN | afadin, adherens junction formation factor | 0.0216232 |
| CADPS | Ca++-dependent secretion activator | 0.0214302 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0213178 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0211155 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0210747 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0210269 |
| OGA | O-GlcNAcase | 0.0208007 |
| RPL37A | ribosomal protein L37a | 0.0207973 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0206561 |
| PIGR | polymeric immunoglobulin receptor | 0.0205889 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0205457 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0204514 |
| EMP1 | epithelial membrane protein 1 | 0.0203323 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0203286 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.020298 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0201986 |
| MTDH | metadherin | 0.0201945 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0200734 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0199782 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0199535 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0199497 |
| CD2AP | CD2-associated protein | 0.0198832 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0198107 |
| RPL28 | ribosomal protein L28 | 0.0195749 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0193851 |
| EPCAM | epithelial cell adhesion molecule | 0.0193611 |
| RPS2 | ribosomal protein S2 | 0.0193505 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0192787 |
| NFIA | nuclear factor I/A | 0.0190358 |
| FNDC3A | fibronectin type III domain containing 3A | 0.019033 |
| RPL36 | ribosomal protein L36 | 0.0189378 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.186897 |
| NPSR1 | neuropeptide S receptor 1 | -0.147382 |
| VCL | vinculin | -0.0643556 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0555247 |
| POTEF | POTE ankyrin domain family, member F | -0.0468082 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0433741 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0421654 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.039855 |
| S100A6 | S100 calcium binding protein A6 | -0.0392087 |
| HMGA1 | high mobility group AT-hook 1 | -0.0380564 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0356716 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0333403 |
| LAMA4 | laminin, alpha 4 | -0.0322344 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0319678 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0295564 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0267085 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.026503 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0264482 |
| KRT18 | keratin 18, type I | -0.0258631 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0249797 |
| RPLP1 | ribosomal protein, large, P1 | -0.0246773 |
| MUC17 | mucin 17, cell surface associated | -0.0236837 |
| RAB10 | RAB10, member RAS oncogene family | -0.0216401 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0208446 |
| KLK10 | kallikrein-related peptidase 10 | -0.020705 |
| GPHN | gephyrin | -0.020623 |
| KRT19 | keratin 19, type I | -0.0204341 |
| RNF217 | ring finger protein 217 | -0.0202651 |
| FERMT1 | fermitin family member 1 | -0.020245 |
| RPS24 | ribosomal protein S24 | -0.0200995 |
| LSAMP | limbic system-associated membrane protein | -0.0200521 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0196955 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0194473 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.018961 |
| FOSL1 | FOS-like antigen 1 | -0.018376 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0179308 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0177924 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0177207 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0176892 |
| PERP | PERP, TP53 apoptosis effector | -0.0172328 |
| CBX3 | chromobox homolog 3 | -0.0171378 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0171289 |
| CALB1 | calbindin 1, 28kDa | -0.0171131 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0169471 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0167723 |
| INSIG1 | insulin induced gene 1 | -0.0164862 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0163106 |
| ACTN4 | actinin, alpha 4 | -0.0163097 |
| FLNB | filamin B, beta | -0.0161174 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0160226 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0158623 |
| IGFL2 | IGF-like family member 2 | -0.0155334 |
| RCOR1 | REST corepressor 1 | -0.0153714 |
| PRSS3 | protease, serine, 3 | -0.0153314 |
| PKM | pyruvate kinase, muscle | -0.0152968 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0148686 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0147052 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0145873 |
| VMP1 | vacuole membrane protein 1 | -0.0144902 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0144503 |
| TPM1 | tropomyosin 1 (alpha) | -0.0144411 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0140978 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0140156 |
| PALLD | palladin, cytoskeletal associated protein | -0.013914 |
| DIAPH3 | diaphanous-related formin 3 | -0.0138328 |
| MLEC | malectin | -0.0137812 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0135759 |
| TUBA1B | tubulin, alpha 1b | -0.0133022 |
| NOSTRIN | nitric oxide synthase trafficking | -0.0132593 |
| PHGR1 | proline/histidine/glycine-rich 1 | -0.0132114 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.013086 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0129899 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0127006 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0126986 |
| WLS | wntless Wnt ligand secretion mediator | -0.0126919 |
| NRXN3 | neurexin 3 | -0.0125204 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0124577 |
| LUZP1 | leucine zipper protein 1 | -0.0124509 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0122768 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0121551 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0121549 |
| EGR1 | early growth response 1 | -0.0121424 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0119423 |
| TFF1 | trefoil factor 1 | -0.0118375 |
| LBR | lamin B receptor | -0.0116956 |
| TPM4 | tropomyosin 4 | -0.0116902 |
| ABLIM1 | actin binding LIM protein 1 | -0.0116366 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0116122 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0114568 |
| RAD51B | RAD51 paralog B | -0.0114075 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0113829 |
| SMAD2 | SMAD family member 2 | -0.0113446 |
| HDAC2 | histone deacetylase 2 | -0.0112537 |
| SH3D19 | SH3 domain containing 19 | -0.0112078 |
| TUBB | tubulin, beta class I | -0.0111193 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0111144 |
| RESF1 | retroelement silencing factor 1 | -0.0110978 |
| PTMA | prothymosin, alpha | -0.0110795 |
| PCDH9 | protocadherin 9 | -0.0110733 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0110731 |
