| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Furosemide_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.130403 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0992804 |
| ANGPTL4 | angiopoietin-like 4 | 0.0947872 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0887238 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0808433 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0752175 |
| KLF6 | Kruppel-like factor 6 | 0.0709903 |
| TMSB4X | thymosin beta 4, X-linked | 0.0650086 |
| HLA-B | major histocompatibility complex, class I, B | 0.0610548 |
| MT1X | metallothionein 1X | 0.0607605 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0606296 |
| PDE10A | phosphodiesterase 10A | 0.0596309 |
| ENO1 | enolase 1, (alpha) | 0.0578021 |
| MT1E | metallothionein 1E | 0.0521682 |
| DST | dystonin | 0.0468062 |
| RAI1 | retinoic acid induced 1 | 0.0460284 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0459517 |
| CD44 | CD44 molecule (Indian blood group) | 0.0457048 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0438751 |
| LOXL2 | lysyl oxidase-like 2 | 0.0436417 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0434199 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0416828 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0409779 |
| RPS8 | ribosomal protein S8 | 0.0408952 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0403494 |
| PYGL | phosphorylase, glycogen, liver | 0.0388537 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0385642 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0384971 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0384656 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0377793 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0373226 |
| TXNIP | thioredoxin interacting protein | 0.0373108 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.037226 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.036238 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0357419 |
| SQSTM1 | sequestosome 1 | 0.0354966 |
| JUN | jun proto-oncogene | 0.0352966 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.03488 |
| FMNL2 | formin-like 2 | 0.0344006 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0338803 |
| RNF213 | ring finger protein 213 | 0.0325707 |
| RUNX1 | runt-related transcription factor 1 | 0.0317323 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0315087 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0310529 |
| RPS12 | ribosomal protein S12 | 0.0310172 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0309582 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0308825 |
| NPAS2 | neuronal PAS domain protein 2 | 0.030567 |
| MEF2A | myocyte enhancer factor 2A | 0.0303477 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0302272 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0300638 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0289775 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0284932 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0284691 |
| NDRG1 | N-myc downstream regulated 1 | 0.0276313 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0273633 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0273048 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0272584 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0265457 |
| EHBP1 | EH domain binding protein 1 | 0.0265132 |
| ACTG1 | actin gamma 1 | 0.0262918 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0256559 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0254992 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0252521 |
| TRIM56 | tripartite motif containing 56 | 0.0252311 |
| JMJD1C | jumonji domain containing 1C | 0.0251921 |
| PCDH1 | protocadherin 1 | 0.0248161 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0244237 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0242948 |
| RPS3 | ribosomal protein S3 | 0.0242245 |
| ANKRD26 | ankyrin repeat domain 26 | 0.0241061 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0240804 |
| EREG | epiregulin | 0.0237964 |
| MYOF | myoferlin | 0.0237104 |
| RPL26 | ribosomal protein L26 | 0.0236998 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0236365 |
| B2M | beta-2-microglobulin | 0.0236279 |
| MXI1 | MAX interactor 1, dimerization protein | 0.023331 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0226392 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0222352 |
| RPL35 | ribosomal protein L35 | 0.0221814 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0221479 |
| HLA-C | major histocompatibility complex, class I, C | 0.0218848 |
| CADM2 | cell adhesion molecule 2 | 0.0216549 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0213522 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.021291 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0212172 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0209493 |
| ADM | adrenomedullin | 0.0209385 |
| ARFGEF3 | ARFGEF family member 3 | 0.0206223 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0206131 |
| RPS27A | ribosomal protein S27a | 0.020591 |
| RPL37 | ribosomal protein L37 | 0.0205597 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0203439 |
| RPL28 | ribosomal protein L28 | 0.020337 |
| PMP22 | peripheral myelin protein 22 | 0.0202553 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0202132 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0201769 |
| ACAD11 | acyl-CoA dehydrogenase family, member 11 | 0.0201182 |
| PRKCE | protein kinase C, epsilon | 0.0200235 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.10258 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0871153 |
| POTEF | POTE ankyrin domain family, member F | -0.0826759 |
| PTMA | prothymosin, alpha | -0.0717402 |
| CENPF | centromere protein F, 350/400kDa | -0.0654805 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0621139 |
| FTL | ferritin, light polypeptide | -0.0600001 |
| TXNRD1 | thioredoxin reductase 1 | -0.0599267 |
| VCL | vinculin | -0.0454852 |
| RPS23 | ribosomal protein S23 | -0.0346562 |
| USP34 | ubiquitin specific peptidase 34 | -0.0343109 |
| RPLP1 | ribosomal protein, large, P1 | -0.0340842 |
| CLTC | clathrin, heavy chain (Hc) | -0.0337311 |
| RPL31 | ribosomal protein L31 | -0.0336757 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0336179 |
| DIAPH3 | diaphanous-related formin 3 | -0.0333578 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0327627 |
| RCOR1 | REST corepressor 1 | -0.0317359 |
| MKI67 | marker of proliferation Ki-67 | -0.0312728 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.030911 |
| ZNF217 | zinc finger protein 217 | -0.0307656 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.029784 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0290628 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0284213 |
| PKM | pyruvate kinase, muscle | -0.0278395 |
| EGR1 | early growth response 1 | -0.0273071 |
| INTS6 | integrator complex subunit 6 | -0.0272939 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.027191 |
| PLK2 | polo-like kinase 2 | -0.0265198 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0263622 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0261494 |
| MAP4 | microtubule-associated protein 4 | -0.0259262 |
| HPCAL1 | hippocalcin-like 1 | -0.0255393 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0253661 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0252386 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0251917 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0251833 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0250687 |
| ECT2 | epithelial cell transforming 2 | -0.0250013 |
| PCBP2 | poly(rC) binding protein 2 | -0.0248107 |
| RBM39 | RNA binding motif protein 39 | -0.0239503 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0235412 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0234528 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0227549 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0227321 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0223836 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0223606 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0222395 |
| GOLGA4 | golgin A4 | -0.0222008 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0220866 |
| RPS24 | ribosomal protein S24 | -0.0220397 |
| RRM2 | ribonucleotide reductase M2 | -0.021756 |
| ANLN | anillin, actin binding protein | -0.021638 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0216374 |
| RPL32 | ribosomal protein L32 | -0.0213396 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0210629 |
| VIM | vimentin | -0.0210545 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0209996 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0208479 |
| TOP1 | topoisomerase (DNA) I | -0.0207827 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0204892 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0203982 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0201898 |
| RPS2 | ribosomal protein S2 | -0.0200956 |
| RPL7 | ribosomal protein L7 | -0.0198174 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0197943 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0197716 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0197464 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0196203 |
| SPAG9 | sperm associated antigen 9 | -0.0193456 |
| EZR | ezrin | -0.0190336 |
| MEMO1 | mediator of cell motility 1 | -0.0188572 |
| TPX2 | TPX2, microtubule-associated | -0.0187385 |
| RPS5 | ribosomal protein S5 | -0.0187197 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0186197 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0185317 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0185091 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0184098 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0184041 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.018274 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0182106 |
| POU2F1 | POU class 2 homeobox 1 | -0.0181027 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0180846 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0180671 |
| RPS17 | ribosomal protein S17 | -0.0179891 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0178784 |
| HDLBP | high density lipoprotein binding protein | -0.0177448 |
| MYO10 | myosin X | -0.0175637 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0175492 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0175416 |
| ANKRD17 | ankyrin repeat domain 17 | -0.017514 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.017408 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0171757 |
| NONO | non-POU domain containing, octamer-binding | -0.017172 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.017138 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0170623 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0170114 |
| GAN | gigaxonin | -0.0170026 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0169988 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0169557 |
