| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Furosemide_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.159443 |
| FAM13A | family with sequence similarity 13, member A | 0.0867163 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0732824 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0675475 |
| NDRG1 | N-myc downstream regulated 1 | 0.0668977 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0637939 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0553065 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0509178 |
| SMAD3 | SMAD family member 3 | 0.046599 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0463284 |
| MT2A | metallothionein 2A | 0.0421526 |
| ARRDC3 | arrestin domain containing 3 | 0.0418444 |
| STC1 | stanniocalcin 1 | 0.0408634 |
| ENO1 | enolase 1, (alpha) | 0.0391322 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0361298 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.030115 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0300143 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0299597 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0299129 |
| ZNF292 | zinc finger protein 292 | 0.0275449 |
| TMEM45B | transmembrane protein 45B | 0.0261517 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0254438 |
| LAMB3 | laminin, beta 3 | 0.0245775 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0237681 |
| SLTM | SAFB-like, transcription modulator | 0.0237159 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0230934 |
| TPD52 | tumor protein D52 | 0.0230258 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.022894 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0228576 |
| B2M | beta-2-microglobulin | 0.0225845 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0222794 |
| SON | SON DNA binding protein | 0.0219071 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0217514 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.021569 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.020779 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0207014 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0206822 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0204036 |
| EFNA5 | ephrin-A5 | 0.019999 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0199945 |
| NGLY1 | N-glycanase 1 | 0.0198606 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0192531 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0192515 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.019111 |
| PDE8A | phosphodiesterase 8A | 0.0182515 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0182038 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0181904 |
| RPS3 | ribosomal protein S3 | 0.0181828 |
| AHNAK | AHNAK nucleoprotein | 0.0170438 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0170346 |
| EMP1 | epithelial membrane protein 1 | 0.0168957 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0168262 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0167872 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0163598 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0159348 |
| FNDC3B | fibronectin type III domain containing 3B | 0.01589 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0158275 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0157595 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0155758 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0154129 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0152615 |
| RNF213 | ring finger protein 213 | 0.0151995 |
| YTHDC1 | YTH domain containing 1 | 0.0151246 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0147209 |
| ANO6 | anoctamin 6 | 0.0147007 |
| CES1 | carboxylesterase 1 | 0.0146993 |
| SLMAP | sarcolemma associated protein | 0.014565 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0145638 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0142515 |
| ATP11A | ATPase, class VI, type 11A | 0.014238 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0140798 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0140775 |
| ZNF638 | zinc finger protein 638 | 0.01407 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0139761 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0139495 |
| FNBP1L | formin binding protein 1-like | 0.0137813 |
| ITSN2 | intersectin 2 | 0.0137239 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0136836 |
| CUL4A | cullin 4A | 0.0136054 |
| TMEM87A | transmembrane protein 87A | 0.0135755 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0134345 |
| RAD51B | RAD51 paralog B | 0.013238 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0132041 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0130914 |
| OGA | O-GlcNAcase | 0.013068 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0130432 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0129953 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0129543 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0129022 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | 0.0128742 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0126996 |
| RPS12 | ribosomal protein S12 | 0.0125588 |
| RUNX1 | runt-related transcription factor 1 | 0.0125368 |
| VEGFA | vascular endothelial growth factor A | 0.0125345 |
| IRS2 | insulin receptor substrate 2 | 0.0125321 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0125152 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0124769 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0123732 |
| MLF1 | myeloid leukemia factor 1 | 0.0123547 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0123338 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0885839 |
| INTS6 | integrator complex subunit 6 | -0.0372094 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0340347 |
| VCL | vinculin | -0.0327488 |
| FTL | ferritin, light polypeptide | -0.0304286 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0289077 |
| PTMA | prothymosin, alpha | -0.0235578 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0224819 |
| HOMER1 | homer scaffolding protein 1 | -0.02093 |
| ASPH | aspartate beta-hydroxylase | -0.0205789 |
| RPLP1 | ribosomal protein, large, P1 | -0.0197621 |
| NABP1 | nucleic acid binding protein 1 | -0.0185525 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0175602 |
| LAMC2 | laminin, gamma 2 | -0.0172011 |
| RPL31 | ribosomal protein L31 | -0.0171993 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0163265 |
| OSMR | oncostatin M receptor | -0.0158576 |
| LMO7 | LIM domain 7 | -0.0153481 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0149977 |
| PKM | pyruvate kinase, muscle | -0.0149206 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0141717 |
| CST3 | cystatin C | -0.0141676 |
| RPS24 | ribosomal protein S24 | -0.0141444 |
| RPS25 | ribosomal protein S25 | -0.0137648 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0124051 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0123215 |
| EGFR | epidermal growth factor receptor | -0.0119323 |
| TUFT1 | tuftelin 1 | -0.0118258 |
| GM2A | GM2 ganglioside activator | -0.0116693 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0116535 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0114666 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0113602 |
| RPS23 | ribosomal protein S23 | -0.0113402 |
| VMP1 | vacuole membrane protein 1 | -0.0111987 |
| MCU | mitochondrial calcium uniporter | -0.0111848 |
| RPL4 | ribosomal protein L4 | -0.0110924 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.01081 |
| ABLIM1 | actin binding LIM protein 1 | -0.010689 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0106559 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0105599 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0104901 |
| TNS3 | tensin 3 | -0.0104358 |
| ACTG1 | actin gamma 1 | -0.0103396 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0103159 |
| FBXO11 | F-box protein 11 | -0.0101551 |
| PATJ | PATJ crumbs cell polarity complex component | -0.010101 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.00986429 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.00972775 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00967702 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.00950968 |
| GSK3B | glycogen synthase kinase 3 beta | -0.00949686 |
| ERI2 | ERI1 exoribonuclease family member 2 | -0.00940497 |
| OXSR1 | oxidative stress responsive 1 | -0.00927955 |
| RCOR1 | REST corepressor 1 | -0.0092263 |
| AEBP2 | AE binding protein 2 | -0.00917401 |
| LDHA | lactate dehydrogenase A | -0.00909905 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.00900185 |
| CCND1 | cyclin D1 | -0.00884897 |
| UBAP1 | ubiquitin associated protein 1 | -0.00864725 |
| TMEM184B | transmembrane protein 184B | -0.00858197 |
| VDAC1 | voltage-dependent anion channel 1 | -0.00854705 |
| WASF2 | WAS protein family, member 2 | -0.0085375 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00840674 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.00840302 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.00836018 |
| KRT86 | keratin 86, type II | -0.0083135 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00829667 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.00812464 |
| SETX | senataxin | -0.00805538 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.00792892 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.00790935 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0078679 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.00771036 |
| RAB10 | RAB10, member RAS oncogene family | -0.00765265 |
| MRPS35 | mitochondrial ribosomal protein S35 | -0.00760114 |
| TPM4 | tropomyosin 4 | -0.00758288 |
| WDR1 | WD repeat domain 1 | -0.00741351 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.00737781 |
| SCEL | sciellin | -0.00730871 |
| SRPRA | SRP receptor subunit alpha | -0.00728356 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.00715008 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.00692744 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00686294 |
| RPS6 | ribosomal protein S6 | -0.00682267 |
| FUS | FUS RNA binding protein | -0.0067986 |
| MOSMO | modulator of smoothened | -0.00674046 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.00673547 |
| AGO3 | argonaute RISC catalytic component 3 | -0.00668844 |
| RPL34 | ribosomal protein L34 | -0.00666211 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.00665466 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.00661338 |
| S100A10 | S100 calcium binding protein A10 | -0.00660506 |
| CUX1 | cut-like homeobox 1 | -0.00660092 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.00658422 |
| RAB3IP | RAB3A interacting protein | -0.00655432 |
| FRMD4B | FERM domain containing 4B | -0.00653027 |
| RPS29 | ribosomal protein S29 | -0.00647893 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.00645927 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0064169 |
| SMIM14 | small integral membrane protein 14 | -0.0063784 |
