| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Furosemide_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.0502154 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0482242 |
| HMGA2 | high mobility group AT-hook 2 | 0.039196 |
| NDRG1 | N-myc downstream regulated 1 | 0.0388641 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0385105 |
| MT2A | metallothionein 2A | 0.0364584 |
| SMAD3 | SMAD family member 3 | 0.0332192 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0315629 |
| FAM13A | family with sequence similarity 13, member A | 0.0313062 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0311695 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0309211 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0308659 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0301825 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0300938 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0300596 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0297922 |
| ANGPTL4 | angiopoietin-like 4 | 0.0292136 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0290361 |
| B2M | beta-2-microglobulin | 0.0272452 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0262174 |
| PCBP2 | poly(rC) binding protein 2 | 0.0261844 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0261376 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0252406 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0249735 |
| HLA-B | major histocompatibility complex, class I, B | 0.0241431 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0236785 |
| RPS12 | ribosomal protein S12 | 0.0236134 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0234753 |
| STC1 | stanniocalcin 1 | 0.0232019 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0225742 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0224402 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0222014 |
| RPS8 | ribosomal protein S8 | 0.022058 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0219367 |
| LOXL2 | lysyl oxidase-like 2 | 0.0218619 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0216923 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0211919 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0210427 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0202684 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0201955 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0199944 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0198161 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0190225 |
| ADM | adrenomedullin | 0.0187065 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0186368 |
| CALU | calumenin | 0.0184532 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0182567 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0179875 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0178411 |
| RPL28 | ribosomal protein L28 | 0.017764 |
| RPL36 | ribosomal protein L36 | 0.0176695 |
| RPL37A | ribosomal protein L37a | 0.0173028 |
| HLA-C | major histocompatibility complex, class I, C | 0.0169124 |
| RPS3 | ribosomal protein S3 | 0.0164564 |
| SEPTIN9 | septin 9 | 0.0164452 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0162148 |
| NAV2 | neuron navigator 2 | 0.0160584 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0158913 |
| TGFB1 | transforming growth factor, beta 1 | 0.0157694 |
| RPL35A | ribosomal protein L35a | 0.0155562 |
| ZNF292 | zinc finger protein 292 | 0.0153129 |
| SYT1 | synaptotagmin I | 0.0150805 |
| G0S2 | G0/G1 switch 2 | 0.0150678 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0150231 |
| SYNJ2 | synaptojanin 2 | 0.0149799 |
| MCL1 | myeloid cell leukemia 1 | 0.0149262 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0147713 |
| EFNA5 | ephrin-A5 | 0.0146652 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0145573 |
| PYGL | phosphorylase, glycogen, liver | 0.0144023 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0140191 |
| GOLGA4 | golgin A4 | 0.0139501 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0139241 |
| ZNF638 | zinc finger protein 638 | 0.0137535 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0132938 |
| RAI14 | retinoic acid induced 14 | 0.0132894 |
| RPS13 | ribosomal protein S13 | 0.0131982 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0131666 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0131389 |
| JUN | jun proto-oncogene | 0.0131257 |
| INTS6 | integrator complex subunit 6 | 0.0130127 |
| HLA-A | major histocompatibility complex, class I, A | 0.0129349 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.012858 |
| TMSB4X | thymosin beta 4, X-linked | 0.0128183 |
| RPS29 | ribosomal protein S29 | 0.012651 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.012592 |
| ANXA1 | annexin A1 | 0.0124949 |
| RARB | retinoic acid receptor, beta | 0.0123449 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0123205 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0121966 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0121296 |
| STXBP1 | syntaxin binding protein 1 | 0.0120663 |
| MT1X | metallothionein 1X | 0.0119273 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0119104 |
| ADD3 | adducin 3 (gamma) | 0.0118586 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0116363 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0116277 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0116054 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0114778 |
| NHSL1 | NHS-like 1 | 0.0114297 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OSMR | oncostatin M receptor | -0.0588873 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0534023 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0533023 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0442751 |
| FN1 | fibronectin 1 | -0.0439837 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0439126 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0408835 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0355057 |
| VIM | vimentin | -0.0330247 |
| TMSB10 | thymosin beta 10 | -0.0300782 |
| KYNU | kynureninase | -0.0296304 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0285391 |
| DST | dystonin | -0.0275908 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0267867 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0238157 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0228968 |
| NRG1 | neuregulin 1 | -0.0220809 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0206112 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0206036 |
| RPL4 | ribosomal protein L4 | -0.01996 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0192772 |
| VCL | vinculin | -0.0192335 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0191595 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0191355 |
| MAP4 | microtubule-associated protein 4 | -0.0187164 |
| PKM | pyruvate kinase, muscle | -0.0184653 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0177329 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0175913 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0172084 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0171373 |
| RBM39 | RNA binding motif protein 39 | -0.0168567 |
| RPLP1 | ribosomal protein, large, P1 | -0.0168377 |
| RAD51B | RAD51 paralog B | -0.0164825 |
| TPM4 | tropomyosin 4 | -0.0160863 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0159919 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0159908 |
| IL6ST | interleukin 6 signal transducer | -0.0154885 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0154005 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0148981 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0144686 |
| COL12A1 | collagen, type XII, alpha 1 | -0.013978 |
| SBF2 | SET binding factor 2 | -0.0138221 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0136006 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0134376 |
| RNF24 | ring finger protein 24 | -0.0134232 |
| TNNC1 | troponin C type 1 (slow) | -0.0132986 |
| CDCP1 | CUB domain containing protein 1 | -0.0131169 |
| USP34 | ubiquitin specific peptidase 34 | -0.013031 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0130137 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0129599 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0129581 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0128872 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0128297 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.01272 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.012002 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0118297 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.011512 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0114872 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0114582 |
| TMEM131 | transmembrane protein 131 | -0.0112625 |
| CDH13 | cadherin 13 | -0.0112004 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0111449 |
| MYOF | myoferlin | -0.0110785 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0109273 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0108869 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.01084 |
| POTEF | POTE ankyrin domain family, member F | -0.0108381 |
| NRP1 | neuropilin 1 | -0.0107801 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0107462 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0107252 |
| MECOM | MDS1 and EVI1 complex locus | -0.0105808 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0105663 |
| TNS3 | tensin 3 | -0.0105527 |
| CCDC68 | coiled-coil domain containing 68 | -0.0104299 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0103611 |
| CANX | calnexin | -0.0102918 |
| PCNX1 | pecanex 1 | -0.0102451 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0102301 |
| FRMD5 | FERM domain containing 5 | -0.0102278 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0101729 |
| PARD3 | par-3 family cell polarity regulator | -0.0101302 |
| MORF4L2 | mortality factor 4 like 2 | -0.0100674 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0100411 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00995993 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.00990261 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00990033 |
| ARF1 | ADP-ribosylation factor 1 | -0.00987639 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.00985956 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.00963807 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.00962546 |
| INSIG1 | insulin induced gene 1 | -0.00945229 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.00942833 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0093903 |
| VMP1 | vacuole membrane protein 1 | -0.00937517 |
| NAV3 | neuron navigator 3 | -0.0093677 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.00935074 |
| AHR | aryl hydrocarbon receptor | -0.00927349 |
| HDLBP | high density lipoprotein binding protein | -0.00926594 |
| MAP1B | microtubule-associated protein 1B | -0.00922668 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.00919292 |
