| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Furosemide_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.100327 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0956641 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0527848 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0427105 |
| MT2A | metallothionein 2A | 0.0415551 |
| WWOX | WW domain containing oxidoreductase | 0.0399023 |
| TPM3 | tropomyosin 3 | 0.0352626 |
| GRAMD1B | GRAM domain containing 1B | 0.0309949 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0303923 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0288145 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.02477 |
| IGF2 | insulin-like growth factor 2 | 0.0238231 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0223907 |
| MCL1 | myeloid cell leukemia 1 | 0.0222873 |
| BRD2 | bromodomain containing 2 | 0.0209802 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0209553 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0205716 |
| ATP11A | ATPase, class VI, type 11A | 0.0198457 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0198226 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0194258 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0190068 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0189762 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0188608 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0188322 |
| ZNF292 | zinc finger protein 292 | 0.0187115 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0187084 |
| RPS8 | ribosomal protein S8 | 0.0186178 |
| FLNA | filamin A, alpha | 0.0182147 |
| FAM107B | family with sequence similarity 107, member B | 0.0180029 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0178318 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0175226 |
| RTN4 | reticulon 4 | 0.0174637 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0166423 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0164288 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0161475 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0159386 |
| HLA-A | major histocompatibility complex, class I, A | 0.0158969 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0156678 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0152993 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0152975 |
| FAT1 | FAT atypical cadherin 1 | 0.0151784 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0150439 |
| ATXN1 | ataxin 1 | 0.0149437 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0148653 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0148376 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0146897 |
| CLU | clusterin | 0.0144142 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0138537 |
| WDR43 | WD repeat domain 43 | 0.0137313 |
| PHIP | pleckstrin homology domain interacting protein | 0.0135623 |
| CCNL1 | cyclin L1 | 0.0135273 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0134502 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0133771 |
| TPD52 | tumor protein D52 | 0.0133754 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0133445 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0132828 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.013217 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0132112 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.01317 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0131357 |
| B2M | beta-2-microglobulin | 0.0130246 |
| RPL28 | ribosomal protein L28 | 0.0129298 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0128941 |
| SPAG9 | sperm associated antigen 9 | 0.0128564 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0128199 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0127399 |
| SIK3 | SIK family kinase 3 | 0.0126255 |
| PCBP2 | poly(rC) binding protein 2 | 0.0125973 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0125174 |
| USP3 | ubiquitin specific peptidase 3 | 0.0124758 |
| BRD4 | bromodomain containing 4 | 0.012412 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.01241 |
| ZNF277 | zinc finger protein 277 | 0.0124042 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0123711 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0123476 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0123043 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0121628 |
| HELZ | helicase with zinc finger | 0.0121354 |
| YBX3 | Y box binding protein 3 | 0.0120087 |
| STC1 | stanniocalcin 1 | 0.011961 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0118946 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0117752 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0117364 |
| LAMA5 | laminin, alpha 5 | 0.0117339 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0117138 |
| RBM25 | RNA binding motif protein 25 | 0.0116616 |
| RAD51B | RAD51 paralog B | 0.0115469 |
| MSN | moesin | 0.0115238 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0113949 |
| AHR | aryl hydrocarbon receptor | 0.0113344 |
| RRM2 | ribonucleotide reductase M2 | 0.0113261 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0111745 |
| NDRG1 | N-myc downstream regulated 1 | 0.0111041 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0110955 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0110924 |
| KIF5B | kinesin family member 5B | 0.0110848 |
| EZR | ezrin | 0.0110347 |
| NCKAP1 | NCK-associated protein 1 | 0.01101 |
| RUNX1 | runt-related transcription factor 1 | 0.0110009 |
| CABIN1 | calcineurin binding protein 1 | 0.010971 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.11428 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0785656 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0737184 |
| VIM | vimentin | -0.0729693 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0636738 |
| LDHA | lactate dehydrogenase A | -0.0426723 |
| FTL | ferritin, light polypeptide | -0.0364393 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0347546 |
| S100A6 | S100 calcium binding protein A6 | -0.0312085 |
| TPM4 | tropomyosin 4 | -0.0310749 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0292043 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0275118 |
| OSMR | oncostatin M receptor | -0.0260949 |
| S100A10 | S100 calcium binding protein A10 | -0.0247248 |
| IER3 | immediate early response 3 | -0.0210842 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0204458 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0202328 |
| PYGL | phosphorylase, glycogen, liver | -0.0199291 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0198483 |
| HDAC9 | histone deacetylase 9 | -0.0194749 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0192001 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0186049 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0175505 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0174927 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0174205 |
| CAVIN1 | caveolae associated protein 1 | -0.0172296 |
| BICC1 | BicC family RNA binding protein 1 | -0.0169509 |
| CFDP1 | craniofacial development protein 1 | -0.0164537 |
| TPM1 | tropomyosin 1 (alpha) | -0.0162828 |
| RPS24 | ribosomal protein S24 | -0.0162063 |
| AK1 | adenylate kinase 1 | -0.016145 |
| USP34 | ubiquitin specific peptidase 34 | -0.0158551 |
| VCL | vinculin | -0.0149585 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0147466 |
| EGFR | epidermal growth factor receptor | -0.0139689 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0139151 |
| PCNX4 | pecanex 4 | -0.0136844 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0136031 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0135014 |
| SERINC3 | serine incorporator 3 | -0.0132189 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0129361 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0128887 |
| RPL4 | ribosomal protein L4 | -0.0128765 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0127534 |
| PARK7 | parkinson protein 7 | -0.0126655 |
| RPLP1 | ribosomal protein, large, P1 | -0.0122901 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.01211 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.012078 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0120524 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0120142 |
| MORF4L2 | mortality factor 4 like 2 | -0.0119864 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0118893 |
| HMGA2 | high mobility group AT-hook 2 | -0.0118447 |
| RPS25 | ribosomal protein S25 | -0.0118106 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0116538 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0116417 |
| THBS1 | thrombospondin 1 | -0.0116128 |
| EHBP1 | EH domain binding protein 1 | -0.0116103 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0116053 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0115263 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0111646 |
| EFNA5 | ephrin-A5 | -0.0110773 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0110374 |
| DST | dystonin | -0.0110033 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0109264 |
| SEPTIN10 | septin 10 | -0.0109078 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0104347 |
| SNX14 | sorting nexin 14 | -0.0103094 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0102638 |
| RPL31 | ribosomal protein L31 | -0.0102073 |
| RAB31 | RAB31, member RAS oncogene family | -0.010015 |
| NAV3 | neuron navigator 3 | -0.00997955 |
| ZNF33A | zinc finger protein 33A | -0.00979575 |
| PCED1B | PC-esterase domain containing 1B | -0.00975234 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00965918 |
| RPL23 | ribosomal protein L23 | -0.00952621 |
| GNAS | GNAS complex locus | -0.00950242 |
| ERBIN | erbb2 interacting protein | -0.00946325 |
| RPL19 | ribosomal protein L19 | -0.00944033 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.00929436 |
| RPS5 | ribosomal protein S5 | -0.00922061 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00922003 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0091836 |
| VDAC1 | voltage-dependent anion channel 1 | -0.00898618 |
| PRR16 | proline rich 16 | -0.00883896 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.00879927 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.00878426 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.00874102 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.00870235 |
| RPL34 | ribosomal protein L34 | -0.00861022 |
| PKM | pyruvate kinase, muscle | -0.00842198 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.00838896 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0083389 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0082888 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.00827189 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.00825334 |
| ATG7 | autophagy related 7 | -0.00821328 |
| FAM110C | family with sequence similarity 110, member C | -0.00820664 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.00818831 |
| SLC35F3 | solute carrier family 35, member F3 | -0.00818496 |
