| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Furosemide_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.0950106 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0690544 |
| ANXA2 | annexin A2 | 0.0662814 |
| IGF2 | insulin-like growth factor 2 | 0.0579323 |
| LMO7 | LIM domain 7 | 0.0574578 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0573213 |
| KYNU | kynureninase | 0.052857 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.052496 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0507394 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0492744 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0492734 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0478658 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0460851 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0446643 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0446047 |
| MYO5B | myosin VB | 0.0441661 |
| NDRG1 | N-myc downstream regulated 1 | 0.043122 |
| EZR | ezrin | 0.0429495 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0419918 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0415275 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0414441 |
| DIAPH1 | diaphanous-related formin 1 | 0.041178 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.040255 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0395857 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.036669 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0365072 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0360109 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0359721 |
| MYO1E | myosin IE | 0.0358599 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0348509 |
| TJP1 | tight junction protein 1 | 0.0344283 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0335946 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0335543 |
| CREBBP | CREB binding protein | 0.033446 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0329904 |
| FAT1 | FAT atypical cadherin 1 | 0.0329742 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0329346 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0328728 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0328108 |
| DSPP | dentin sialophosphoprotein | 0.0324715 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0323921 |
| LAMB3 | laminin, beta 3 | 0.0323525 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0317961 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.031284 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0311452 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0302849 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.030172 |
| MUC16 | mucin 16, cell surface associated | 0.0301537 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0296434 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0295988 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0293226 |
| RYBP | RING1 and YY1 binding protein | 0.0283757 |
| USP53 | ubiquitin specific peptidase 53 | 0.0282085 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.028206 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0281311 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0276007 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0275078 |
| C3 | complement component 3 | 0.0274121 |
| EGR1 | early growth response 1 | 0.0268085 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0266337 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0265931 |
| RNF213 | ring finger protein 213 | 0.0265436 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0264342 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0264118 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0259598 |
| PRKCSH | protein kinase C substrate 80K-H | 0.025047 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0249359 |
| EXOC1 | exocyst complex component 1 | 0.0246854 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0246409 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0245263 |
| HLA-A | major histocompatibility complex, class I, A | 0.0245185 |
| GPC6 | glypican 6 | 0.0241963 |
| SPAG9 | sperm associated antigen 9 | 0.0241932 |
| SRI | sorcin | 0.0240371 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0240306 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.023857 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0238042 |
| USP34 | ubiquitin specific peptidase 34 | 0.0237776 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0236698 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0235452 |
| TXNIP | thioredoxin interacting protein | 0.0235125 |
| RUNX1 | runt-related transcription factor 1 | 0.0234964 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0234507 |
| CUX1 | cut-like homeobox 1 | 0.0232984 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0232342 |
| SLTM | SAFB-like, transcription modulator | 0.0231157 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0228883 |
| H3-3B | H3.3 histone B | 0.0228441 |
| JUP | junction plakoglobin | 0.0227015 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0226223 |
| CDYL | chromodomain protein, Y-like | 0.0220718 |
| DUSP4 | dual specificity phosphatase 4 | 0.0218677 |
| B2M | beta-2-microglobulin | 0.0218437 |
| MFF | mitochondrial fission factor | 0.0217473 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0216934 |
| MYO6 | myosin VI | 0.0214745 |
| VCL | vinculin | 0.0214722 |
| CNKSR3 | CNKSR family member 3 | 0.0214035 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0213236 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0212723 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.144941 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.143026 |
| FTL | ferritin, light polypeptide | -0.0890077 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0824453 |
| VIM | vimentin | -0.0823132 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0649644 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0601957 |
| RPLP1 | ribosomal protein, large, P1 | -0.0515218 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0503046 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.048297 |
| RPS16 | ribosomal protein S16 | -0.0467576 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0432578 |
| TMSB10 | thymosin beta 10 | -0.0426525 |
| FMNL2 | formin-like 2 | -0.0418799 |
| STC1 | stanniocalcin 1 | -0.0418553 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0412184 |
| SQSTM1 | sequestosome 1 | -0.0395747 |
| RPL35A | ribosomal protein L35a | -0.0395618 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0395056 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0386994 |
| RPL5 | ribosomal protein L5 | -0.0380622 |
| RPS6 | ribosomal protein S6 | -0.0374737 |
| MMP12 | matrix metallopeptidase 12 | -0.0372716 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0371598 |
| MMP1 | matrix metallopeptidase 1 | -0.0370969 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0366816 |
| RPL26 | ribosomal protein L26 | -0.0366718 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0357828 |
| SBF2 | SET binding factor 2 | -0.0354157 |
| POTEF | POTE ankyrin domain family, member F | -0.0351563 |
| KRT17 | keratin 17, type I | -0.0342874 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0337365 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0337273 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0336168 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0328066 |
| ATOSA | atos homolog A | -0.0328037 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0324963 |
| MT2A | metallothionein 2A | -0.0324321 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0319521 |
| MORF4L2 | mortality factor 4 like 2 | -0.0317983 |
| LDHA | lactate dehydrogenase A | -0.0317652 |
| CALR | calreticulin | -0.0316331 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0307888 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0306699 |
| OXR1 | oxidation resistance 1 | -0.0305177 |
| ACTG1 | actin gamma 1 | -0.0304394 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0302132 |
| ADM | adrenomedullin | -0.0300836 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0300509 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0300284 |
| TXNRD1 | thioredoxin reductase 1 | -0.0298181 |
| RPL19 | ribosomal protein L19 | -0.0293372 |
| CDK17 | cyclin-dependent kinase 17 | -0.0290853 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0290598 |
| FBXO11 | F-box protein 11 | -0.0286821 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0286027 |
| RPL4 | ribosomal protein L4 | -0.0283461 |
| IER3 | immediate early response 3 | -0.0280543 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0276459 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0273221 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.02732 |
| RPL38 | ribosomal protein L38 | -0.0272341 |
| SET | SET nuclear proto-oncogene | -0.0265582 |
| SMAD3 | SMAD family member 3 | -0.0264979 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0263452 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0262621 |
| YTHDC1 | YTH domain containing 1 | -0.0261518 |
| FAM13A | family with sequence similarity 13, member A | -0.0259818 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0256203 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0252684 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0250138 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0248949 |
| RPS2 | ribosomal protein S2 | -0.0248445 |
| UBC | ubiquitin C | -0.0245169 |
| JMJD1C | jumonji domain containing 1C | -0.0243412 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0242604 |
| S100A6 | S100 calcium binding protein A6 | -0.0242249 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0242183 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.024157 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0241441 |
| NPTN | neuroplastin | -0.0241253 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0238616 |
| ANO6 | anoctamin 6 | -0.0238374 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0237858 |
| RPL37 | ribosomal protein L37 | -0.0237391 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0236628 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0233799 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0231925 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0230045 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0225198 |
| DIAPH3 | diaphanous-related formin 3 | -0.0224545 |
| RAB10 | RAB10, member RAS oncogene family | -0.0224213 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0223528 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0222739 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0221431 |
| GPHN | gephyrin | -0.0221341 |
| RPL11 | ribosomal protein L11 | -0.0221224 |
| RACK1 | receptor for activated C kinase 1 | -0.0220017 |
| XPO1 | exportin 1 | -0.0218858 |
| TPI1 | triosephosphate isomerase 1 | -0.0217773 |
