| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Furosemide_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.18155 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0689766 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0666048 |
| AHNAK | AHNAK nucleoprotein | 0.0617001 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0588025 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0513928 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0448814 |
| TPM3 | tropomyosin 3 | 0.0377327 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0371533 |
| TXNRD1 | thioredoxin reductase 1 | 0.0347501 |
| COPA | coatomer protein complex, subunit alpha | 0.0339719 |
| ADAR | adenosine deaminase, RNA-specific | 0.0331589 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0325678 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0322929 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0322396 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0315664 |
| ATP11A | ATPase, class VI, type 11A | 0.0313597 |
| TLN1 | talin 1 | 0.0312094 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0295142 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0287859 |
| RPS8 | ribosomal protein S8 | 0.028134 |
| OGA | O-GlcNAcase | 0.0277804 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0274427 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0270164 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0262814 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.026062 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0258068 |
| CANX | calnexin | 0.0256317 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0255341 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0254068 |
| H1-0 | H1.0 linker histone | 0.0252492 |
| SRP72 | signal recognition particle 72kDa | 0.025105 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0248775 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0244525 |
| CAVIN1 | caveolae associated protein 1 | 0.0244235 |
| NABP1 | nucleic acid binding protein 1 | 0.0243313 |
| SPAG9 | sperm associated antigen 9 | 0.0226693 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0225151 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0219051 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0217318 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0214585 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0210327 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0208675 |
| PREPL | prolyl endopeptidase-like | 0.0205948 |
| STC1 | stanniocalcin 1 | 0.0202676 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.01987 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0198036 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0195564 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0195532 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0194625 |
| ZFR | zinc finger RNA binding protein | 0.0193794 |
| ENO1 | enolase 1, (alpha) | 0.0190173 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0187227 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0186089 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0185487 |
| FBXO11 | F-box protein 11 | 0.0183457 |
| ATF6 | activating transcription factor 6 | 0.0182973 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0177022 |
| HLA-C | major histocompatibility complex, class I, C | 0.0175893 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0175459 |
| KLF6 | Kruppel-like factor 6 | 0.0175123 |
| KIF1A | kinesin family member 1A | 0.0171474 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0170962 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0168643 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0168519 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0167335 |
| VMP1 | vacuole membrane protein 1 | 0.0166545 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0166078 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0164105 |
| EPN2 | epsin 2 | 0.0161825 |
| CALU | calumenin | 0.0161567 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0160779 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0159212 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0159211 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0158275 |
| PHF21A | PHD finger protein 21A | 0.0158237 |
| GPHN | gephyrin | 0.0155135 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0154697 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0153584 |
| FMNL2 | formin-like 2 | 0.0152027 |
| PRKCE | protein kinase C, epsilon | 0.0151259 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0151086 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0147637 |
| LOXL2 | lysyl oxidase-like 2 | 0.0147203 |
| TJP1 | tight junction protein 1 | 0.0146685 |
| RPN1 | ribophorin I | 0.0146313 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0145672 |
| HELZ | helicase with zinc finger | 0.0144947 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0144111 |
| RPS3 | ribosomal protein S3 | 0.0144052 |
| HDAC4 | histone deacetylase 4 | 0.0143322 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0142869 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0141957 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0140976 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0140277 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0139945 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0139671 |
| JUN | jun proto-oncogene | 0.0139011 |
| HDLBP | high density lipoprotein binding protein | 0.013858 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0137626 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.137318 |
| VIM | vimentin | -0.0800765 |
| POTEF | POTE ankyrin domain family, member F | -0.0580409 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0457274 |
| PTMA | prothymosin, alpha | -0.044309 |
| TPI1 | triosephosphate isomerase 1 | -0.043527 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0414653 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0410923 |
| VCL | vinculin | -0.035114 |
| OSMR | oncostatin M receptor | -0.0339931 |
| RYR3 | ryanodine receptor 3 | -0.0333298 |
| HLA-B | major histocompatibility complex, class I, B | -0.0291731 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0281626 |
| TUBA1B | tubulin, alpha 1b | -0.027902 |
| CENPF | centromere protein F, 350/400kDa | -0.026734 |
| TPM4 | tropomyosin 4 | -0.024678 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0245561 |
| HMGA2 | high mobility group AT-hook 2 | -0.0243517 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0232001 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0228904 |
| EGR1 | early growth response 1 | -0.0221932 |
| TAPBP | TAP binding protein (tapasin) | -0.0214587 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0214429 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0203265 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0202669 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0201825 |
| CBX3 | chromobox homolog 3 | -0.0197539 |
| LDHA | lactate dehydrogenase A | -0.0189608 |
| RPS21 | ribosomal protein S21 | -0.0186791 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0185153 |
| FMN1 | formin 1 | -0.0184905 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0184727 |
| RPS24 | ribosomal protein S24 | -0.0184034 |
| PKM | pyruvate kinase, muscle | -0.0182573 |
| RPL9 | ribosomal protein L9 | -0.0179345 |
| KLHL5 | kelch-like family member 5 | -0.0176914 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0176315 |
| RPL32 | ribosomal protein L32 | -0.0176123 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0175416 |
| FTL | ferritin, light polypeptide | -0.0170401 |
| BSG | basigin (Ok blood group) | -0.0168086 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0166653 |
| RPL11 | ribosomal protein L11 | -0.0164585 |
| SETD5 | SET domain containing 5 | -0.0164146 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0163725 |
| CDK17 | cyclin-dependent kinase 17 | -0.0162104 |
| RPS6 | ribosomal protein S6 | -0.0161438 |
| PFN1 | profilin 1 | -0.0160497 |
| USP34 | ubiquitin specific peptidase 34 | -0.0160457 |
| CALD1 | caldesmon 1 | -0.0160076 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0158939 |
| GNAS | GNAS complex locus | -0.0158601 |
| RPL31 | ribosomal protein L31 | -0.0157104 |
| RPS19 | ribosomal protein S19 | -0.0156622 |
| RPLP1 | ribosomal protein, large, P1 | -0.0155676 |
| RNF145 | ring finger protein 145 | -0.0154891 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0151382 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0147938 |
| BMP5 | bone morphogenetic protein 5 | -0.0146176 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0145594 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0144534 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0143489 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.014084 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0140572 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0139596 |
| TUBA1C | tubulin, alpha 1c | -0.0139588 |
| TPX2 | TPX2, microtubule-associated | -0.0137455 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0137001 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0135565 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0135232 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0134578 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0134303 |
| CCDC91 | coiled-coil domain containing 91 | -0.0134159 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0133318 |
| S100A10 | S100 calcium binding protein A10 | -0.0130207 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0129525 |
| HMGA1 | high mobility group AT-hook 1 | -0.012704 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.0125023 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0124891 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0124038 |
| PNN | pinin, desmosome associated protein | -0.0123453 |
| TPM2 | tropomyosin 2 (beta) | -0.0123158 |
| ADRM1 | adhesion regulating molecule 1 | -0.0122917 |
| KIF18B | kinesin family member 18B | -0.0122721 |
| RBM25 | RNA binding motif protein 25 | -0.0122701 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0121115 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0119263 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0119178 |
| RPS5 | ribosomal protein S5 | -0.0118707 |
| COL5A2 | collagen, type V, alpha 2 | -0.0118092 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0116442 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0114628 |
| ZNF644 | zinc finger protein 644 | -0.0112703 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0112601 |
| NLGN1 | neuroligin 1 | -0.0112416 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0112323 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.011187 |
| MT2A | metallothionein 2A | -0.0111498 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0111012 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0110857 |
