| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Furosemide_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.100193 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.083631 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0639794 |
| RPS12 | ribosomal protein S12 | 0.0606764 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.05669 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0562103 |
| MCL1 | myeloid cell leukemia 1 | 0.0557117 |
| RPS8 | ribosomal protein S8 | 0.0534533 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0526762 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0505277 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0494972 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0466909 |
| RPS3 | ribosomal protein S3 | 0.0421807 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0418525 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0409461 |
| FMNL2 | formin-like 2 | 0.0402797 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0383513 |
| STC1 | stanniocalcin 1 | 0.0380361 |
| RPL37A | ribosomal protein L37a | 0.0378341 |
| SPAG9 | sperm associated antigen 9 | 0.0373562 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0371769 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0369814 |
| FNDC3A | fibronectin type III domain containing 3A | 0.036479 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0351933 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0343957 |
| NDRG1 | N-myc downstream regulated 1 | 0.0334037 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0322398 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0317889 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0317489 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0317116 |
| LSAMP | limbic system-associated membrane protein | 0.0315664 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0314356 |
| INHBA | inhibin, beta A | 0.0314211 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0308339 |
| CD109 | CD109 molecule | 0.0302318 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0299642 |
| CDH13 | cadherin 13 | 0.0298566 |
| HLA-A | major histocompatibility complex, class I, A | 0.0295375 |
| SQSTM1 | sequestosome 1 | 0.0292052 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0289484 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0287076 |
| COL5A2 | collagen, type V, alpha 2 | 0.0282467 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0272602 |
| CD44 | CD44 molecule (Indian blood group) | 0.027254 |
| ANXA2 | annexin A2 | 0.0272378 |
| TPM3 | tropomyosin 3 | 0.0267838 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0262069 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0254715 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0254582 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0254227 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0253737 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0250611 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0249138 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0238629 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0237363 |
| RPS27A | ribosomal protein S27a | 0.0235822 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0233867 |
| IL6 | interleukin 6 | 0.0231818 |
| UBC | ubiquitin C | 0.0231374 |
| PCBP2 | poly(rC) binding protein 2 | 0.023065 |
| PYGL | phosphorylase, glycogen, liver | 0.0229264 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0228976 |
| RAD51B | RAD51 paralog B | 0.022618 |
| RPS2 | ribosomal protein S2 | 0.0225552 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0225176 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0220056 |
| KYNU | kynureninase | 0.022004 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0218909 |
| AUTS2 | autism susceptibility candidate 2 | 0.0217341 |
| IRS2 | insulin receptor substrate 2 | 0.0216143 |
| MFSD12 | major facilitator superfamily domain containing 12 | 0.0212649 |
| B2M | beta-2-microglobulin | 0.0212575 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0211814 |
| ENO1 | enolase 1, (alpha) | 0.0204997 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0201508 |
| COPA | coatomer protein complex, subunit alpha | 0.0201435 |
| SVIL | supervillin | 0.0200922 |
| FNIP1 | folliculin interacting protein 1 | 0.0198848 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0197236 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0196009 |
| XYLT1 | xylosyltransferase I | 0.0192851 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0192511 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 0.0191544 |
| RPL9 | ribosomal protein L9 | 0.0190866 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0187435 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0186715 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0181971 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0181158 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0180915 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0180653 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0180131 |
| POTEF | POTE ankyrin domain family, member F | 0.017816 |
| EGR1 | early growth response 1 | 0.0178007 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.017679 |
| RACK1 | receptor for activated C kinase 1 | 0.0176464 |
| NUP58 | nucleoporin 58 | 0.0175602 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0172793 |
| TMEM144 | transmembrane protein 144 | 0.0172691 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0171334 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.016911 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.134575 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0977168 |
| TXNRD1 | thioredoxin reductase 1 | -0.0907039 |
| EFNA5 | ephrin-A5 | -0.0877371 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0747215 |
| RPLP1 | ribosomal protein, large, P1 | -0.061814 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.06078 |
| ASPH | aspartate beta-hydroxylase | -0.0575975 |
| FTL | ferritin, light polypeptide | -0.0472685 |
| PTMA | prothymosin, alpha | -0.0397234 |
| MYOF | myoferlin | -0.0396944 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0395092 |
| NRCAM | neuronal cell adhesion molecule | -0.0389295 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0339784 |
| MT2A | metallothionein 2A | -0.0337005 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0320576 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0319929 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0296028 |
| GRAMD1B | GRAM domain containing 1B | -0.0289905 |
| CANX | calnexin | -0.0271581 |
| TNPO1 | transportin 1 | -0.0270435 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0267238 |
| RPS24 | ribosomal protein S24 | -0.0267221 |
| PTGR1 | prostaglandin reductase 1 | -0.0262826 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0250725 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0247594 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0245969 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.023655 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0236089 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0230259 |
| VIM | vimentin | -0.0228851 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0227295 |
| RPL31 | ribosomal protein L31 | -0.0226511 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0218959 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0213442 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0211108 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0209889 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0209142 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0207899 |
| RRBP1 | ribosome binding protein 1 | -0.0207277 |
| PHF20 | PHD finger protein 20 | -0.0204512 |
| RPL23 | ribosomal protein L23 | -0.0194486 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0192978 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.019148 |
| VCL | vinculin | -0.0191004 |
| PALLD | palladin, cytoskeletal associated protein | -0.0188873 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0188033 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0186468 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.018247 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0180478 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0180056 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0178336 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0176693 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0175668 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0170842 |
| RPL4 | ribosomal protein L4 | -0.0168891 |
| KIF21A | kinesin family member 21A | -0.016843 |
| OGA | O-GlcNAcase | -0.0166425 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.0166041 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0164773 |
| RPL32 | ribosomal protein L32 | -0.0158509 |
| TKT | transketolase | -0.0157281 |
| MORF4L2 | mortality factor 4 like 2 | -0.0155704 |
| LAMA1 | laminin, alpha 1 | -0.0154858 |
| NEK7 | NIMA-related kinase 7 | -0.0154512 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0154447 |
| ZNF804A | zinc finger protein 804A | -0.0153194 |
| TBXT | T-box transcription factor T | -0.0152931 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0152925 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0151809 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.015175 |
| HDLBP | high density lipoprotein binding protein | -0.0151212 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0149589 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0149536 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.0147826 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.014734 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0146503 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0144793 |
| GDA | guanine deaminase | -0.0144753 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0144219 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0142773 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0142381 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0142312 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0142023 |
| RPL19 | ribosomal protein L19 | -0.0141801 |
| PLCB4 | phospholipase C, beta 4 | -0.014179 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0141676 |
| PCBP3 | poly(rC) binding protein 3 | -0.0141091 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0140845 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0139191 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0138682 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0138163 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0137622 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0133165 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | -0.0132327 |
| RPS4X | ribosomal protein S4, X-linked | -0.0132209 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0132011 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0131314 |
| LAMB1 | laminin, beta 1 | -0.0131131 |
| APP | amyloid beta (A4) precursor protein | -0.0129335 |
