| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Furosemide_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.123083 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0656802 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0456849 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0407888 |
| COL5A2 | collagen, type V, alpha 2 | 0.0389342 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.033288 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0303908 |
| CCN2 | cellular communication network factor 2 | 0.0296968 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0279838 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0250911 |
| MED12L | mediator complex subunit 12-like | 0.0238747 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0236818 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0236331 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0235835 |
| NTM | neurotrimin | 0.023347 |
| MED13L | mediator complex subunit 13-like | 0.0230366 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0229572 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0223248 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0218109 |
| CADM2 | cell adhesion molecule 2 | 0.0216305 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0208087 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0200364 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0199057 |
| FAT1 | FAT atypical cadherin 1 | 0.0195928 |
| PDGFC | platelet derived growth factor C | 0.0194025 |
| XPO1 | exportin 1 | 0.0187117 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.018489 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0179853 |
| PEG10 | paternally expressed 10 | 0.0176673 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0176622 |
| TPR | translocated promoter region, nuclear basket protein | 0.016933 |
| TENM3 | teneurin transmembrane protein 3 | 0.0168945 |
| WWOX | WW domain containing oxidoreductase | 0.0166817 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0164505 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0164366 |
| TBC1D5 | TBC1 domain family, member 5 | 0.01614 |
| PCDH7 | protocadherin 7 | 0.0159774 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0159315 |
| AHNAK | AHNAK nucleoprotein | 0.0157791 |
| MKI67 | marker of proliferation Ki-67 | 0.0157749 |
| CDH19 | cadherin 19, type 2 | 0.0157339 |
| CENPF | centromere protein F, 350/400kDa | 0.0156997 |
| FOXG1 | forkhead box G1 | 0.0156039 |
| ZNF608 | zinc finger protein 608 | 0.015575 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0154601 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0146611 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0144568 |
| MYO9A | myosin IXA | 0.0140065 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0136087 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0135059 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0133831 |
| TGFB2 | transforming growth factor, beta 2 | 0.0133636 |
| DST | dystonin | 0.0130739 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0130203 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0129886 |
| NBEA | neurobeachin | 0.0129618 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0124796 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0122329 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0122027 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0121898 |
| H1-0 | H1.0 linker histone | 0.0121008 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0120799 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0119633 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0119366 |
| VEGFA | vascular endothelial growth factor A | 0.0117345 |
| FN1 | fibronectin 1 | 0.0116581 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0115243 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0113218 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0113032 |
| LPIN2 | lipin 2 | 0.0112598 |
| ITSN2 | intersectin 2 | 0.0112078 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0111904 |
| GSE1 | Gse1 coiled-coil protein | 0.0111388 |
| BBX | bobby sox homolog (Drosophila) | 0.0109887 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0108951 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0108326 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0108244 |
| RANBP17 | RAN binding protein 17 | 0.010796 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0105242 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0104127 |
| CASC3 | cancer susceptibility candidate 3 | 0.0104021 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0103921 |
| SAMD11 | sterile alpha motif domain containing 11 | 0.0103065 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0101823 |
| ADAR | adenosine deaminase, RNA-specific | 0.0101771 |
| YTHDC1 | YTH domain containing 1 | 0.0101501 |
| SVIL | supervillin | 0.0101374 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.010104 |
| EXOC4 | exocyst complex component 4 | 0.0100988 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0100954 |
| ZNF146 | zinc finger protein 146 | 0.0100893 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0100674 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.00997022 |
| PNN | pinin, desmosome associated protein | 0.0099562 |
| MCL1 | myeloid cell leukemia 1 | 0.00992955 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.00987969 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.00973351 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00970475 |
| PCNT | pericentrin | 0.00968796 |
| SMC4 | structural maintenance of chromosomes 4 | 0.009658 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102811 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0597969 |
| TMSB10 | thymosin beta 10 | -0.056338 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0496592 |
| PTMA | prothymosin, alpha | -0.0457642 |
| VIM | vimentin | -0.0391212 |
| HDAC9 | histone deacetylase 9 | -0.0351354 |
| PLPP1 | phospholipid phosphatase 1 | -0.0327009 |
| NRG1 | neuregulin 1 | -0.0326753 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0322715 |
| SNX6 | sorting nexin 6 | -0.0307875 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0292199 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.028525 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0274848 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0274545 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0260192 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0258638 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0249347 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0243887 |
| PCDH9 | protocadherin 9 | -0.0243537 |
| RPS16 | ribosomal protein S16 | -0.0240976 |
| SYT1 | synaptotagmin I | -0.0230151 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0224247 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0221436 |
| SRP54 | signal recognition particle 54kDa | -0.021381 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0213023 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0200661 |
| NEBL | nebulette | -0.0199897 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0193863 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0193709 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0192021 |
| SPAG9 | sperm associated antigen 9 | -0.018992 |
| ATXN2 | ataxin 2 | -0.0187147 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0183751 |
| RBM20 | RNA binding motif protein 20 | -0.0182479 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0182138 |
| TCF12 | transcription factor 12 | -0.0176817 |
| RAB31 | RAB31, member RAS oncogene family | -0.0173354 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0173347 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0173228 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0172977 |
| RPLP1 | ribosomal protein, large, P1 | -0.0171924 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0167947 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0166933 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.016594 |
| RHEB | Ras homolog enriched in brain | -0.0164212 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0162887 |
| MYO10 | myosin X | -0.0160857 |
| TENM2 | teneurin transmembrane protein 2 | -0.0157407 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0156375 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0150166 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0149838 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.01494 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0147297 |
| GNAS | GNAS complex locus | -0.0147091 |
| HDAC2 | histone deacetylase 2 | -0.0146982 |
| ITGAV | integrin, alpha V | -0.0146413 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0144814 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0143922 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0139434 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0138452 |
| PHF3 | PHD finger protein 3 | -0.0138072 |
| MORF4L2 | mortality factor 4 like 2 | -0.0137378 |
| MATR3 | matrin 3 | -0.0136752 |
| EMP1 | epithelial membrane protein 1 | -0.0134505 |
| NPR2 | natriuretic peptide receptor 2 | -0.0133189 |
| NOP58 | NOP58 ribonucleoprotein | -0.0132645 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0132595 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.013259 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0132587 |
| TUT4 | terminal uridylyl transferase 4 | -0.0132541 |
| ANK2 | ankyrin 2, neuronal | -0.0132348 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0131993 |
| NXN | nucleoredoxin | -0.0131789 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0131106 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0129191 |
| RCOR1 | REST corepressor 1 | -0.0129021 |
| RFPL4B | ret finger protein-like 4B | -0.0128938 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0127555 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0127478 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.012728 |
| NUP153 | nucleoporin 153kDa | -0.0126994 |
| FILIP1 | filamin A interacting protein 1 | -0.0125843 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0125722 |
| HMGA1 | high mobility group AT-hook 1 | -0.0124734 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0123992 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0122273 |
| TP53BP2 | tumor protein p53 binding protein 2 | -0.0121795 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0121375 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0120799 |
| UBE3C | ubiquitin protein ligase E3C | -0.0120695 |
| PLK2 | polo-like kinase 2 | -0.0120328 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0118336 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0118079 |
| TPM1 | tropomyosin 1 (alpha) | -0.0117499 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0117218 |
| LUZP2 | leucine zipper protein 2 | -0.0117054 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | -0.0116841 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0116697 |
| CLTC | clathrin, heavy chain (Hc) | -0.0115829 |
