| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Furosemide_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS8 | ribosomal protein S8 | 0.0791768 |
| TMSB4X | thymosin beta 4, X-linked | 0.0763234 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0502888 |
| PDGFC | platelet derived growth factor C | 0.0450262 |
| RPS3 | ribosomal protein S3 | 0.0411876 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0407681 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0377341 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0347399 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0338054 |
| HDAC9 | histone deacetylase 9 | 0.0332086 |
| TJP1 | tight junction protein 1 | 0.0310186 |
| RPS2 | ribosomal protein S2 | 0.0305697 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0279255 |
| MACROD2 | MACRO domain containing 2 | 0.0275279 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0264411 |
| RPL35A | ribosomal protein L35a | 0.0248761 |
| B2M | beta-2-microglobulin | 0.0239771 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0237144 |
| RPS12 | ribosomal protein S12 | 0.023335 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0230783 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0227201 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0224622 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.020297 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0202512 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0193109 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0186258 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.018458 |
| GSE1 | Gse1 coiled-coil protein | 0.0182968 |
| RIGI | RNA sensor RIG-I | 0.0179893 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.017889 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0177625 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0176567 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0174135 |
| RPL37A | ribosomal protein L37a | 0.0174058 |
| RPS14 | ribosomal protein S14 | 0.0172338 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0172049 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0171228 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0170507 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0168727 |
| RPL8 | ribosomal protein L8 | 0.0168199 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0164588 |
| RPS13 | ribosomal protein S13 | 0.0163004 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0162099 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0161158 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0160442 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0160088 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0157493 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0157153 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0155225 |
| MKI67 | marker of proliferation Ki-67 | 0.015376 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0150604 |
| PFN1 | profilin 1 | 0.0148072 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0145431 |
| ANXA1 | annexin A1 | 0.0140689 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0140667 |
| SON | SON DNA binding protein | 0.0139772 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0139387 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0138421 |
| PMP22 | peripheral myelin protein 22 | 0.0138391 |
| ENO1 | enolase 1, (alpha) | 0.0135874 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0135833 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0135529 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.013482 |
| PRDX2 | peroxiredoxin 2 | 0.01345 |
| ANKRD12 | ankyrin repeat domain 12 | 0.013352 |
| ADAR | adenosine deaminase, RNA-specific | 0.0133394 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0131761 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0131692 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0128516 |
| BRD4 | bromodomain containing 4 | 0.0126095 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0124631 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0123477 |
| MYO5C | myosin VC | 0.0123277 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0123247 |
| TPM3 | tropomyosin 3 | 0.0122927 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0122572 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0121453 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0121044 |
| SEPTIN7 | septin 7 | 0.0119781 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0118821 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0116969 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0116071 |
| RPL36 | ribosomal protein L36 | 0.0114469 |
| VEGFA | vascular endothelial growth factor A | 0.011394 |
| UBXN4 | UBX domain protein 4 | 0.0113177 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0112623 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0112613 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0112598 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0112067 |
| LONRF2 | LON peptidase N-terminal domain and ring finger 2 | 0.0111904 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0110886 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0110437 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0109638 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0109617 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0109509 |
| FN1 | fibronectin 1 | 0.0109335 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0109091 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0109087 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0109065 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0106772 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.109855 |
| PTMA | prothymosin, alpha | -0.0957911 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0840958 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0599916 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.053309 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.052256 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0448553 |
| RPLP1 | ribosomal protein, large, P1 | -0.0437216 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0410664 |
| VCL | vinculin | -0.0400634 |
| EZR | ezrin | -0.0391113 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0382893 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0349991 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0346448 |
| S100A6 | S100 calcium binding protein A6 | -0.0325465 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0310924 |
| UBC | ubiquitin C | -0.0302539 |
| RPL4 | ribosomal protein L4 | -0.0292679 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0278224 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0270491 |
| GOLGA4 | golgin A4 | -0.0259006 |
| BMP10 | bone morphogenetic protein 10 | -0.0256935 |
| EGFR | epidermal growth factor receptor | -0.0248255 |
| TXNRD1 | thioredoxin reductase 1 | -0.0234568 |
| LDHA | lactate dehydrogenase A | -0.0233158 |
| RPS24 | ribosomal protein S24 | -0.0221333 |
| CCND1 | cyclin D1 | -0.0221293 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0216318 |
| GPATCH8 | G patch domain containing 8 | -0.0215615 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0213449 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0212897 |
| FLNB | filamin B, beta | -0.0209283 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0208688 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0206582 |
| ASPH | aspartate beta-hydroxylase | -0.0205589 |
| RPL31 | ribosomal protein L31 | -0.0201374 |
| PHF3 | PHD finger protein 3 | -0.0200672 |
| HDLBP | high density lipoprotein binding protein | -0.0200625 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0197955 |
| GNAS | GNAS complex locus | -0.0194887 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0191664 |
| MAP4 | microtubule-associated protein 4 | -0.0191423 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0186865 |
| RPL5 | ribosomal protein L5 | -0.0184437 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0183134 |
| TNPO1 | transportin 1 | -0.0180239 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0180131 |
| RPL12 | ribosomal protein L12 | -0.0177716 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0176072 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0174357 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0173293 |
| TMSB10 | thymosin beta 10 | -0.0170172 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0169373 |
| RPL23 | ribosomal protein L23 | -0.0168608 |
| HJURP | Holliday junction recognition protein | -0.0168472 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0168049 |
| RPL27A | ribosomal protein L27a | -0.0165619 |
| RAD21 | RAD21 homolog (S. pombe) | -0.016508 |
| EVI5 | ecotropic viral integration site 5 | -0.0163864 |
| RPLP0 | ribosomal protein, large, P0 | -0.0162228 |
| MATR3 | matrin 3 | -0.016136 |
| FUS | FUS RNA binding protein | -0.0161306 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0156335 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0155291 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0155068 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0154592 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0153546 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0151713 |
| DGKH | diacylglycerol kinase, eta | -0.0150815 |
| RBM25 | RNA binding motif protein 25 | -0.015044 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0150178 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0146462 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0146237 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0145099 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0142154 |
| ZNF106 | zinc finger protein 106 | -0.0141472 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0141261 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0141082 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0140475 |
| IPO7 | importin 7 | -0.0140443 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0139274 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0137851 |
| EXOC6B | exocyst complex component 6B | -0.0137467 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0134608 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0134467 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0133202 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0133065 |
| RPS21 | ribosomal protein S21 | -0.013269 |
| CANX | calnexin | -0.013112 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0130884 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0130612 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0130419 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0129175 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0128917 |
| ANK2 | ankyrin 2, neuronal | -0.012885 |
| TMEM135 | transmembrane protein 135 | -0.0128393 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0128308 |
| TUBB | tubulin, beta class I | -0.0128155 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0128072 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0127843 |
