| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Furosemide_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.10958 |
| VEGFA | vascular endothelial growth factor A | 0.10213 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0931281 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0632566 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0592844 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.058763 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0534912 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0527558 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0514401 |
| ENO1 | enolase 1, (alpha) | 0.0508375 |
| MT2A | metallothionein 2A | 0.0503515 |
| HLA-E | major histocompatibility complex, class I, E | 0.0490192 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0483075 |
| ADM | adrenomedullin | 0.046547 |
| STC1 | stanniocalcin 1 | 0.0459071 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.043631 |
| AHNAK | AHNAK nucleoprotein | 0.0415916 |
| TMSB4X | thymosin beta 4, X-linked | 0.0391764 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0390117 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0384431 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0381243 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0375765 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0371628 |
| ARRDC3 | arrestin domain containing 3 | 0.0370152 |
| SQSTM1 | sequestosome 1 | 0.0351005 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0345363 |
| ZNF292 | zinc finger protein 292 | 0.0342562 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0336502 |
| FNIP1 | folliculin interacting protein 1 | 0.0334229 |
| CANX | calnexin | 0.0330399 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0325034 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0317626 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0317484 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0316682 |
| HLA-C | major histocompatibility complex, class I, C | 0.0312264 |
| RPS3 | ribosomal protein S3 | 0.0280149 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0276106 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0275709 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0268583 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0265545 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0255636 |
| OGA | O-GlcNAcase | 0.025534 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0254702 |
| CDK19 | cyclin-dependent kinase 19 | 0.0250332 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0248065 |
| LOXL2 | lysyl oxidase-like 2 | 0.0246208 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0243262 |
| HLA-A | major histocompatibility complex, class I, A | 0.0241463 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0241015 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0240522 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0239997 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0235065 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0234557 |
| RPS8 | ribosomal protein S8 | 0.0231585 |
| ATXN1 | ataxin 1 | 0.0229679 |
| ANXA2 | annexin A2 | 0.0226756 |
| FMNL2 | formin-like 2 | 0.0226313 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0224714 |
| HDAC9 | histone deacetylase 9 | 0.0224576 |
| ARFGEF3 | ARFGEF family member 3 | 0.0223242 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0222468 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0219996 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0215944 |
| RPS12 | ribosomal protein S12 | 0.021586 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0213146 |
| CUL4B | cullin 4B | 0.0212335 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0211592 |
| SMAD3 | SMAD family member 3 | 0.0209953 |
| FAM13A | family with sequence similarity 13, member A | 0.0205969 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0204924 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0204249 |
| ANXA1 | annexin A1 | 0.0200753 |
| PGM3 | phosphoglucomutase 3 | 0.0196121 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0193 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0192956 |
| SMAP1 | small ArfGAP 1 | 0.0186658 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0186299 |
| GOLGB1 | golgin B1 | 0.0186181 |
| PGK1 | phosphoglycerate kinase 1 | 0.0183352 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0181555 |
| GOLGA4 | golgin A4 | 0.0179353 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0178414 |
| HLA-B | major histocompatibility complex, class I, B | 0.0177659 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0177271 |
| KIF13A | kinesin family member 13A | 0.0175054 |
| RND3 | Rho family GTPase 3 | 0.0172926 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0169751 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0169629 |
| COL5A1 | collagen, type V, alpha 1 | 0.0169071 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0168575 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0166771 |
| MLPH | melanophilin | 0.0166162 |
| TRAM2 | translocation associated membrane protein 2 | 0.0165781 |
| PDE10A | phosphodiesterase 10A | 0.0165683 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0162652 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0162446 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0161856 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.016029 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.015988 |
| TMEM132D | transmembrane protein 132D | 0.0158709 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.145427 |
| FRMD4A | FERM domain containing 4A | -0.103451 |
| TMSB10 | thymosin beta 10 | -0.0897148 |
| FN1 | fibronectin 1 | -0.0677782 |
| VCL | vinculin | -0.0641005 |
| GLIS3 | GLIS family zinc finger 3 | -0.0579623 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0505015 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0501575 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0485582 |
| FTL | ferritin, light polypeptide | -0.042767 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0379781 |
| BICC1 | BicC family RNA binding protein 1 | -0.0351607 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0342374 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0341844 |
| TPM4 | tropomyosin 4 | -0.0334344 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0324087 |
| RIGI | RNA sensor RIG-I | -0.0307176 |
| HMGA2 | high mobility group AT-hook 2 | -0.030011 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0275607 |
| VCAN | versican | -0.0275479 |
| KYNU | kynureninase | -0.0274388 |
| RPS24 | ribosomal protein S24 | -0.0266882 |
| CADM1 | cell adhesion molecule 1 | -0.0265111 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0233932 |
| RPL23 | ribosomal protein L23 | -0.0230252 |
| PALLD | palladin, cytoskeletal associated protein | -0.0225627 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0221701 |
| OSMR | oncostatin M receptor | -0.021815 |
| RPLP1 | ribosomal protein, large, P1 | -0.0216963 |
| EGR1 | early growth response 1 | -0.0208093 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0206787 |
| CENPF | centromere protein F, 350/400kDa | -0.0204905 |
| CTSD | cathepsin D | -0.0204641 |
| TNNC1 | troponin C type 1 (slow) | -0.0200238 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0199906 |
| CLMP | CXADR-like membrane protein | -0.0198738 |
| TAPBP | TAP binding protein (tapasin) | -0.0197129 |
| INHBA | inhibin, beta A | -0.0193534 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0192619 |
| CLIC4 | chloride intracellular channel 4 | -0.0192514 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0191528 |
| VMP1 | vacuole membrane protein 1 | -0.0190505 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0188014 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0187576 |
| RRBP1 | ribosome binding protein 1 | -0.0183867 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0182802 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0178945 |
| MAP4 | microtubule-associated protein 4 | -0.0178694 |
| THBS1 | thrombospondin 1 | -0.0174333 |
| IL6 | interleukin 6 | -0.0174332 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0174112 |
| RBM39 | RNA binding motif protein 39 | -0.0172206 |
| HMGA1 | high mobility group AT-hook 1 | -0.017161 |
| TUBB | tubulin, beta class I | -0.0169402 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0167878 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.016458 |
| RNF24 | ring finger protein 24 | -0.0162908 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0160448 |
| NAV1 | neuron navigator 1 | -0.0160419 |
| TPM1 | tropomyosin 1 (alpha) | -0.015978 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0159689 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0159404 |
| COL1A1 | collagen, type I, alpha 1 | -0.0155558 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0152811 |
| KRT19 | keratin 19, type I | -0.0152157 |
| AFAP1 | actin filament associated protein 1 | -0.0151808 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0147408 |
| DENND5A | DENN/MADD domain containing 5A | -0.014713 |
| WTAP | Wilms tumor 1 associated protein | -0.0146698 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0144406 |
| GNAS | GNAS complex locus | -0.0143348 |
| RPL31 | ribosomal protein L31 | -0.0142488 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0141688 |
| MSN | moesin | -0.0141253 |
| SERINC3 | serine incorporator 3 | -0.0140799 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0139766 |
| RPS21 | ribosomal protein S21 | -0.0139746 |
| FBXO11 | F-box protein 11 | -0.0138854 |
| MAP1B | microtubule-associated protein 1B | -0.0138711 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0136734 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0135882 |
| RTN4 | reticulon 4 | -0.0135148 |
| ERBIN | erbb2 interacting protein | -0.0135139 |
| PKM | pyruvate kinase, muscle | -0.0133697 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0133034 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0132478 |
| PLPP3 | phospholipid phosphatase 3 | -0.0132304 |
| POTEF | POTE ankyrin domain family, member F | -0.0132271 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.013207 |
| ACTN1 | actinin, alpha 1 | -0.01319 |
| FRMD5 | FERM domain containing 5 | -0.0131802 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0131459 |
| IER3 | immediate early response 3 | -0.0130779 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0130459 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0130184 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0130124 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0129971 |
| CDH13 | cadherin 13 | -0.0129695 |
| SMAD2 | SMAD family member 2 | -0.0129541 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0128868 |
