| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Furosemide perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Furosemide_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.233751 |
| FN1 | fibronectin 1 | 0.148406 |
| VEGFA | vascular endothelial growth factor A | 0.0913218 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0856395 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0796546 |
| NDRG1 | N-myc downstream regulated 1 | 0.075613 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0616632 |
| TXNIP | thioredoxin interacting protein | 0.055709 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0554636 |
| STC2 | stanniocalcin 2 | 0.052405 |
| FAM13A | family with sequence similarity 13, member A | 0.0509381 |
| HLA-B | major histocompatibility complex, class I, B | 0.0501096 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0471957 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0465471 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0461635 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0449394 |
| SQSTM1 | sequestosome 1 | 0.0439581 |
| RPL35A | ribosomal protein L35a | 0.0416922 |
| CD109 | CD109 molecule | 0.0411305 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0402346 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0398606 |
| RPS12 | ribosomal protein S12 | 0.0390443 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0384957 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0383082 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.038244 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0369534 |
| B2M | beta-2-microglobulin | 0.0365122 |
| ITGA1 | integrin, alpha 1 | 0.0364694 |
| RPS8 | ribosomal protein S8 | 0.0353456 |
| RPL37A | ribosomal protein L37a | 0.0349141 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.033695 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0332021 |
| DENND5B | DENN/MADD domain containing 5B | 0.0331692 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0322204 |
| DUSP6 | dual specificity phosphatase 6 | 0.0315705 |
| RPS27 | ribosomal protein S27 | 0.0314867 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0304978 |
| NRP1 | neuropilin 1 | 0.0299711 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0286782 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0280327 |
| ENO1 | enolase 1, (alpha) | 0.0273424 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.027106 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0262794 |
| HLA-A | major histocompatibility complex, class I, A | 0.0262524 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0260797 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0260118 |
| EFNA5 | ephrin-A5 | 0.0255923 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0251586 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0248582 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0245281 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0245215 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0245094 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0238911 |
| GOLGA4 | golgin A4 | 0.0237316 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0236744 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0231232 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0227296 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0227141 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0225972 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0224399 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0224082 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0222611 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0222587 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0221904 |
| CDK13 | cyclin-dependent kinase 13 | 0.0221123 |
| CD44 | CD44 molecule (Indian blood group) | 0.0217068 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0215869 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.021573 |
| ADAR | adenosine deaminase, RNA-specific | 0.021444 |
| SIRT1 | sirtuin 1 | 0.0213815 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 0.0213403 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0209993 |
| MTDH | metadherin | 0.0206917 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0202932 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0202093 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0201872 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0200799 |
| HLA-C | major histocompatibility complex, class I, C | 0.0200353 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0199943 |
| ANGPTL4 | angiopoietin-like 4 | 0.0196871 |
| OSMR | oncostatin M receptor | 0.0194875 |
| RPS11 | ribosomal protein S11 | 0.0194824 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0194582 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0193701 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0192854 |
| RPS3 | ribosomal protein S3 | 0.0191516 |
| AREG | amphiregulin | 0.0190581 |
| AOPEP | aminopeptidase O (putative) | 0.0189496 |
| RPS6 | ribosomal protein S6 | 0.0187754 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0187495 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0187375 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0186435 |
| DSG2 | desmoglein 2 | 0.0186157 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0185488 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0183243 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0183166 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0182846 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0179925 |
| TMEM165 | transmembrane protein 165 | 0.0179365 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0179069 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.152451 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.145007 |
| VCL | vinculin | -0.129865 |
| PTMA | prothymosin, alpha | -0.103925 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0905234 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0776102 |
| VIM | vimentin | -0.0619558 |
| UBC | ubiquitin C | -0.0602865 |
| S100A6 | S100 calcium binding protein A6 | -0.0585906 |
| CENPF | centromere protein F, 350/400kDa | -0.0518238 |
| HMGA2 | high mobility group AT-hook 2 | -0.0478678 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0455132 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0438703 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0437185 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.04062 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0395152 |
| AEBP2 | AE binding protein 2 | -0.039192 |
| POTEF | POTE ankyrin domain family, member F | -0.0377913 |
| ASPH | aspartate beta-hydroxylase | -0.0375864 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0370134 |
| IER3 | immediate early response 3 | -0.0364707 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0361664 |
| MKI67 | marker of proliferation Ki-67 | -0.0354918 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0336364 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.032067 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0310546 |
| RPLP1 | ribosomal protein, large, P1 | -0.0292595 |
| PALLD | palladin, cytoskeletal associated protein | -0.0282772 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0279804 |
| NTN4 | netrin 4 | -0.0270868 |
| INTS6 | integrator complex subunit 6 | -0.026649 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0256171 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0252497 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0250471 |
| FTL | ferritin, light polypeptide | -0.0250212 |
| PKM | pyruvate kinase, muscle | -0.0246261 |
| WDR1 | WD repeat domain 1 | -0.0246043 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0240329 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0239684 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0239358 |
| ETV1 | ets variant 1 | -0.0238417 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0237709 |
| RAB31 | RAB31, member RAS oncogene family | -0.0237239 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0232825 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0231918 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0229434 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0229225 |
| RPS27A | ribosomal protein S27a | -0.0226888 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0225094 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.022431 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0221009 |
| HMGA1 | high mobility group AT-hook 1 | -0.0220676 |
| CANX | calnexin | -0.022067 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0219907 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0218786 |
| RPS24 | ribosomal protein S24 | -0.021789 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0216752 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0215185 |
| VMP1 | vacuole membrane protein 1 | -0.0212023 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0209014 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0208109 |
| TFG | TRK-fused gene | -0.0207357 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0204136 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0203295 |
| ACTN1 | actinin, alpha 1 | -0.020319 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0202945 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0202867 |
| PCBP2 | poly(rC) binding protein 2 | -0.0202054 |
| RHEB | Ras homolog enriched in brain | -0.0200575 |
| TPM4 | tropomyosin 4 | -0.019968 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0197906 |
| RBM39 | RNA binding motif protein 39 | -0.0197551 |
| JUN | jun proto-oncogene | -0.0197197 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0194866 |
| TUFT1 | tuftelin 1 | -0.0193956 |
| RPS5 | ribosomal protein S5 | -0.0193819 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.0193267 |
| RBM25 | RNA binding motif protein 25 | -0.0192639 |
| DIAPH3 | diaphanous-related formin 3 | -0.0191977 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0191118 |
| SPAG9 | sperm associated antigen 9 | -0.0187722 |
| RAB10 | RAB10, member RAS oncogene family | -0.0187144 |
| LAP3 | leucine aminopeptidase 3 | -0.0185725 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0185459 |
| FAM20C | family with sequence similarity 20, member C | -0.0185397 |
| LDHA | lactate dehydrogenase A | -0.0184847 |
| CORO1C | coronin, actin binding protein, 1C | -0.0184428 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0182293 |
| IL6ST | interleukin 6 signal transducer | -0.0181813 |
| HMGB3 | high mobility group box 3 | -0.0180011 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0179828 |
| NAV2 | neuron navigator 2 | -0.0179114 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0177629 |
| EGR1 | early growth response 1 | -0.0177172 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0176603 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | -0.0176496 |
| RRBP1 | ribosome binding protein 1 | -0.0176352 |
| RUNX1 | runt-related transcription factor 1 | -0.01742 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0172039 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0171616 |
