| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.204845 |
| MT2A | metallothionein 2A | 0.127329 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.123648 |
| DST | dystonin | 0.116526 |
| ASPH | aspartate beta-hydroxylase | 0.090062 |
| PKM | pyruvate kinase, muscle | 0.0885889 |
| CDH13 | cadherin 13 | 0.0877392 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.082109 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0784186 |
| CD44 | CD44 molecule (Indian blood group) | 0.0781975 |
| ENO1 | enolase 1, (alpha) | 0.0687357 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0682831 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0668562 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0665488 |
| CALR | calreticulin | 0.0664169 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0631197 |
| LDHA | lactate dehydrogenase A | 0.0630287 |
| TPM3 | tropomyosin 3 | 0.0622232 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0609761 |
| CENPF | centromere protein F, 350/400kDa | 0.0568357 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0557443 |
| HDAC9 | histone deacetylase 9 | 0.0541479 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0536748 |
| FSTL1 | follistatin-like 1 | 0.0530415 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0529778 |
| DSPP | dentin sialophosphoprotein | 0.0524214 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0513531 |
| EZR | ezrin | 0.0501969 |
| COL5A1 | collagen, type V, alpha 1 | 0.0496611 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.048583 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0474607 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.047402 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0471182 |
| PRELID2 | PRELI domain containing 2 | 0.0468349 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0445196 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0433821 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.043349 |
| MT1X | metallothionein 1X | 0.0425509 |
| EFNA5 | ephrin-A5 | 0.0419417 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0416353 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.041406 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0402101 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0401127 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.039225 |
| NEK7 | NIMA-related kinase 7 | 0.0379926 |
| APP | amyloid beta (A4) precursor protein | 0.0379796 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0378827 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0376677 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0368634 |
| MB21D2 | Mab-21 domain containing 2 | 0.0360441 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0354742 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0352475 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0347083 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.033716 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0335878 |
| CYTH3 | cytohesin 3 | 0.033359 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.033124 |
| SON | SON DNA binding protein | 0.0326787 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0325682 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.032129 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0320906 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0320033 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0319251 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0318382 |
| TAGLN2 | transgelin 2 | 0.0316659 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0313914 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0312695 |
| MYOF | myoferlin | 0.031263 |
| CANX | calnexin | 0.0309821 |
| POTEF | POTE ankyrin domain family, member F | 0.0309113 |
| GLIS3 | GLIS family zinc finger 3 | 0.0307349 |
| TPR | translocated promoter region, nuclear basket protein | 0.0300891 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0299833 |
| RRM2 | ribonucleotide reductase M2 | 0.0299683 |
| EGFR | epidermal growth factor receptor | 0.0299012 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0297097 |
| ANLN | anillin, actin binding protein | 0.0293704 |
| MAP1B | microtubule-associated protein 1B | 0.0292622 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0286408 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0284089 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0281802 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.028051 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0279979 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0279892 |
| RNF213 | ring finger protein 213 | 0.0279017 |
| FLNA | filamin A, alpha | 0.0276054 |
| DNMBP | dynamin binding protein | 0.0275616 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0272877 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0269527 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0266466 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0265809 |
| PLXNA2 | plexin A2 | 0.0265761 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0260923 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0258564 |
| DIAPH3 | diaphanous-related formin 3 | 0.0256725 |
| MKI67 | marker of proliferation Ki-67 | 0.0256709 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0256229 |
| SMAD3 | SMAD family member 3 | 0.0255746 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0255674 |
| ERBIN | erbb2 interacting protein | 0.0254385 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.307556 |
| VIM | vimentin | -0.212165 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180081 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0870359 |
| FBN1 | fibrillin 1 | -0.0866485 |
| COL1A2 | collagen, type I, alpha 2 | -0.0854782 |
| S100A10 | S100 calcium binding protein A10 | -0.0773976 |
| CD99 | CD99 molecule | -0.0662853 |
| MYADM | myeloid-associated differentiation marker | -0.0564285 |
| MX2 | MX dynamin-like GTPase 2 | -0.050213 |
| LOXL2 | lysyl oxidase-like 2 | -0.0500537 |
| SUCNR1 | succinate receptor 1 | -0.0496879 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0481387 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0456543 |
| AUTS2 | autism susceptibility candidate 2 | -0.0451412 |
| AHNAK | AHNAK nucleoprotein | -0.0444282 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0442551 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0434227 |
| HLA-B | major histocompatibility complex, class I, B | -0.041616 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0411518 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0411426 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0410194 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0405315 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0396704 |
| UBC | ubiquitin C | -0.0382138 |
| CCND1 | cyclin D1 | -0.0381164 |
| SBF2 | SET binding factor 2 | -0.0364663 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0364559 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0343326 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0332423 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0331311 |
| INSIG1 | insulin induced gene 1 | -0.0316112 |
| MEIS2 | Meis homeobox 2 | -0.0312431 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0301912 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0296351 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0296077 |
| HLA-E | major histocompatibility complex, class I, E | -0.0290604 |
| GPC6 | glypican 6 | -0.0288615 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0279479 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0276416 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0272935 |
| TNS3 | tensin 3 | -0.0264164 |
| EPAS1 | endothelial PAS domain protein 1 | -0.025542 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0254234 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0253241 |
| KRT81 | keratin 81, type II | -0.0242489 |
| PXDN | peroxidasin | -0.0241489 |
| NDRG1 | N-myc downstream regulated 1 | -0.0239145 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0238255 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0236073 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0232126 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0229859 |
| STC1 | stanniocalcin 1 | -0.0226524 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0222901 |
| PTMA | prothymosin, alpha | -0.0221168 |
| WTAP | Wilms tumor 1 associated protein | -0.0217379 |
| FNBP1 | formin binding protein 1 | -0.0216304 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0216085 |
| FRMD5 | FERM domain containing 5 | -0.0215994 |
| RTN4 | reticulon 4 | -0.0215609 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0213846 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0213506 |
| RPS15 | ribosomal protein S15 | -0.0211466 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0211335 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0210351 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0208031 |
| THY1 | Thy-1 cell surface antigen | -0.0207996 |
| ACTG1 | actin gamma 1 | -0.0206504 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0204296 |
| NAV1 | neuron navigator 1 | -0.0200734 |
| HLA-C | major histocompatibility complex, class I, C | -0.0199301 |
| TPM1 | tropomyosin 1 (alpha) | -0.0194562 |
| RPL28 | ribosomal protein L28 | -0.0194185 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0192274 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0190842 |
| SP3 | Sp3 transcription factor | -0.0190214 |
| BSG | basigin (Ok blood group) | -0.0188165 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0188 |
| HLA-A | major histocompatibility complex, class I, A | -0.0186564 |
| KLHL24 | kelch-like family member 24 | -0.0186277 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0186079 |
| CLU | clusterin | -0.0184015 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0182817 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0178274 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0175765 |
| TAPBP | TAP binding protein (tapasin) | -0.0175695 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0173906 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0172337 |
| COL5A2 | collagen, type V, alpha 2 | -0.0172197 |
| HIP1 | huntingtin interacting protein 1 | -0.0172117 |
| COL1A1 | collagen, type I, alpha 1 | -0.01712 |
| SLC38A1 | solute carrier family 38, member 1 | -0.017056 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.017006 |
| ZNF609 | zinc finger protein 609 | -0.0168705 |
| GNAS | GNAS complex locus | -0.0168633 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0168494 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0167221 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0167028 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0166316 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.016613 |
