| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.238209 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.173565 |
| HMGA2 | high mobility group AT-hook 2 | 0.160724 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.142772 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.131199 |
| NLGN1 | neuroligin 1 | 0.125254 |
| RRM2 | ribonucleotide reductase M2 | 0.0910396 |
| YAP1 | Yes-associated protein 1 | 0.0857807 |
| ASPH | aspartate beta-hydroxylase | 0.0845139 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0809101 |
| INTS6 | integrator complex subunit 6 | 0.0795725 |
| ADIPOR2 | adiponectin receptor 2 | 0.0698474 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0685748 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0645805 |
| CALR | calreticulin | 0.0645356 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.062189 |
| JMJD1C | jumonji domain containing 1C | 0.0619947 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.061676 |
| ANXA1 | annexin A1 | 0.0616235 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0602341 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0601575 |
| DST | dystonin | 0.0557428 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0541556 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0537682 |
| WWOX | WW domain containing oxidoreductase | 0.0530937 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0520286 |
| ENO1 | enolase 1, (alpha) | 0.051945 |
| DENND5A | DENN/MADD domain containing 5A | 0.0518881 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0516537 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0505188 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0502351 |
| CANX | calnexin | 0.0482253 |
| ZNF638 | zinc finger protein 638 | 0.0472139 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0459299 |
| PCDH9 | protocadherin 9 | 0.0451423 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0431944 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0428283 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0427043 |
| NHSL1 | NHS-like 1 | 0.0422996 |
| TPM3 | tropomyosin 3 | 0.0421269 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0410016 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0402885 |
| EHBP1 | EH domain binding protein 1 | 0.039994 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0398846 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0386132 |
| PRKCE | protein kinase C, epsilon | 0.0381098 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0375644 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0374427 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0369822 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0369349 |
| XPOT | exportin, tRNA | 0.0367109 |
| ANKRD11 | ankyrin repeat domain 11 | 0.03669 |
| PRELID2 | PRELI domain containing 2 | 0.0365745 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0365189 |
| PKM | pyruvate kinase, muscle | 0.0358499 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0356176 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0354587 |
| EXOC4 | exocyst complex component 4 | 0.035398 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0351261 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0350757 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0348232 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0347663 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0339255 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0330425 |
| ETV6 | ets variant 6 | 0.0327351 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0320192 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0318629 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0317427 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0316938 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0312162 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0305406 |
| RNF213 | ring finger protein 213 | 0.0304686 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0303974 |
| ALMS1 | Alstrom syndrome protein 1 | 0.0303766 |
| MKI67 | marker of proliferation Ki-67 | 0.0301342 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0300429 |
| R3HDM2 | R3H domain containing 2 | 0.0299753 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0297583 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0297282 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0296846 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0296429 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0295302 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.029526 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0295209 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0292381 |
| COMMD10 | COMM domain containing 10 | 0.0287299 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0284597 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0284332 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0284144 |
| NEBL | nebulette | 0.0282347 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0281966 |
| SKIL | SKI-like proto-oncogene | 0.027928 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0278043 |
| RPL41 | ribosomal protein L41 | 0.0276416 |
| LRRC23 | leucine rich repeat containing 23 | 0.0276001 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.02758 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0275191 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.027229 |
| PTMA | prothymosin, alpha | 0.0270907 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0269626 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.283252 |
| VIM | vimentin | -0.129648 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0863983 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0839333 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0720119 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0673499 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0541625 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0517778 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0476151 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.045436 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0447845 |
| AREG | amphiregulin | -0.0444907 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0418514 |
| MGAT4C | MGAT4 family, member C | -0.0412651 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0405929 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0405375 |
| NEK7 | NIMA-related kinase 7 | -0.0398109 |
| TXNRD1 | thioredoxin reductase 1 | -0.0393122 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0363851 |
| KLHL24 | kelch-like family member 24 | -0.0363465 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0363325 |
| HMGA1 | high mobility group AT-hook 1 | -0.0361904 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0337953 |
| CCN2 | cellular communication network factor 2 | -0.0323384 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0321623 |
| EDN1 | endothelin 1 | -0.0318284 |
| RPS16 | ribosomal protein S16 | -0.0315833 |
| PFN1 | profilin 1 | -0.031441 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0308378 |
| RPLP0 | ribosomal protein, large, P0 | -0.0303802 |
| CCNL1 | cyclin L1 | -0.0301735 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0293896 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0284506 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0277968 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0277446 |
| KIF5B | kinesin family member 5B | -0.0277333 |
| ZFR | zinc finger RNA binding protein | -0.0276306 |
| RPS6 | ribosomal protein S6 | -0.0273445 |
| CLDN1 | claudin 1 | -0.0271263 |
| SYT1 | synaptotagmin I | -0.0269863 |
| TMEM123 | transmembrane protein 123 | -0.0267843 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.026276 |
| OXR1 | oxidation resistance 1 | -0.0262549 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0259928 |
| RPL11 | ribosomal protein L11 | -0.0256409 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.025422 |
| WASF2 | WAS protein family, member 2 | -0.0252586 |
| CPOX | coproporphyrinogen oxidase | -0.0252583 |
| YBX1 | Y box binding protein 1 | -0.025133 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.024748 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0244019 |
| HLA-A | major histocompatibility complex, class I, A | -0.0243673 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0238395 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0235842 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0235474 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.0231391 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0230877 |
| RPL8 | ribosomal protein L8 | -0.0227096 |
| SBF2 | SET binding factor 2 | -0.0226136 |
| WDR43 | WD repeat domain 43 | -0.0226095 |
| RPS23 | ribosomal protein S23 | -0.022392 |
| BCHE | butyrylcholinesterase | -0.0222254 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.022061 |
| RPS5 | ribosomal protein S5 | -0.0210756 |
| ETNK1 | ethanolamine kinase 1 | -0.0210464 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0209329 |
| CDK17 | cyclin-dependent kinase 17 | -0.0208861 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0208839 |
| RNF13 | ring finger protein 13 | -0.0207767 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0202415 |
| THOC1 | THO complex 1 | -0.0201751 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0201279 |
| LDHB | lactate dehydrogenase B | -0.0199784 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0199524 |
| RPLP2 | ribosomal protein, large, P2 | -0.0199202 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0198658 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0198468 |
| PRKCI | protein kinase C, iota | -0.0197025 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0196575 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0195939 |
| S100A6 | S100 calcium binding protein A6 | -0.0195628 |
| PLK2 | polo-like kinase 2 | -0.0194502 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0190978 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.019047 |
| SLC49A4 | solute carrier family 49 member 4 | -0.0190296 |
| RPL32 | ribosomal protein L32 | -0.0189832 |
| MPG | N-methylpurine-DNA glycosylase | -0.018972 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0187202 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0185346 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.0183154 |
| CCNI | cyclin I | -0.0182139 |
| RPS25 | ribosomal protein S25 | -0.0181713 |
| DTNA | dystrobrevin, alpha | -0.0181459 |
| MATR3 | matrin 3 | -0.0181412 |
| NIPSNAP2 | nipsnap homolog 2 | -0.018128 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0181161 |
| SETD5 | SET domain containing 5 | -0.0180785 |
| TSPAN5 | tetraspanin 5 | -0.0180537 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0180469 |
| IPMK | inositol polyphosphate multikinase | -0.0179634 |
