| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.243005 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.152195 |
| RNF213 | ring finger protein 213 | 0.121295 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.116972 |
| SMAD3 | SMAD family member 3 | 0.106559 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0837576 |
| TXNRD1 | thioredoxin reductase 1 | 0.0813913 |
| NAV2 | neuron navigator 2 | 0.0812593 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0786821 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0784862 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0757965 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0751664 |
| CD44 | CD44 molecule (Indian blood group) | 0.0748327 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0723871 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0668935 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0599794 |
| MX1 | MX dynamin-like GTPase 1 | 0.0592218 |
| SEPTIN9 | septin 9 | 0.0573149 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0543087 |
| DIAPH3 | diaphanous-related formin 3 | 0.0505761 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0463608 |
| FAT1 | FAT atypical cadherin 1 | 0.0459896 |
| PKM | pyruvate kinase, muscle | 0.0458942 |
| EFNA5 | ephrin-A5 | 0.0448853 |
| MSN | moesin | 0.044739 |
| NRP2 | neuropilin 2 | 0.044729 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0444555 |
| IFI44L | interferon-induced protein 44-like | 0.0439842 |
| DST | dystonin | 0.0438331 |
| RRM2 | ribonucleotide reductase M2 | 0.0436886 |
| ACTN4 | actinin, alpha 4 | 0.0425298 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0416145 |
| TGM2 | transglutaminase 2 | 0.0413207 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0408862 |
| CTBP2 | C-terminal binding protein 2 | 0.0406257 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0400044 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0399905 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0394531 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0384058 |
| IFI44 | interferon-induced protein 44 | 0.0383908 |
| MYOF | myoferlin | 0.0379699 |
| RUNX1 | runt-related transcription factor 1 | 0.0372683 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0361392 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0355737 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0354995 |
| TLE4 | transducin-like enhancer of split 4 | 0.0346324 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0343688 |
| NFIB | nuclear factor I/B | 0.0341891 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0334342 |
| TPM3 | tropomyosin 3 | 0.0332831 |
| PLEC | plectin | 0.0326403 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0319138 |
| EGFR | epidermal growth factor receptor | 0.0318593 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0315865 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0315697 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0312061 |
| JAK1 | Janus kinase 1 | 0.0309276 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0307467 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0306864 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0301054 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.029353 |
| GLIS3 | GLIS family zinc finger 3 | 0.0288521 |
| APP | amyloid beta (A4) precursor protein | 0.0287322 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0286005 |
| MCL1 | myeloid cell leukemia 1 | 0.0284871 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0284691 |
| PAX8 | paired box 8 | 0.0281937 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0281721 |
| FLNB | filamin B, beta | 0.0278541 |
| WWOX | WW domain containing oxidoreductase | 0.0278179 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0277908 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0277622 |
| CORO1C | coronin, actin binding protein, 1C | 0.0275208 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0273005 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0269818 |
| RAD51B | RAD51 paralog B | 0.0269571 |
| FUS | FUS RNA binding protein | 0.0269563 |
| PFKP | phosphofructokinase, platelet | 0.0269494 |
| ANLN | anillin, actin binding protein | 0.0267955 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0258418 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0257525 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0255926 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0253651 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0253624 |
| ERBIN | erbb2 interacting protein | 0.0253443 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0250365 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.025025 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0249108 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0246711 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0243678 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0240708 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0239687 |
| HKDC1 | hexokinase domain containing 1 | 0.0237989 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0237112 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0234012 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0232609 |
| ZNF638 | zinc finger protein 638 | 0.0231715 |
| FLNA | filamin A, alpha | 0.0231465 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0231338 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0229457 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.23485 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.11064 |
| TMSB10 | thymosin beta 10 | -0.100805 |
| VIM | vimentin | -0.0978457 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0941749 |
| CP | ceruloplasmin (ferroxidase) | -0.0894844 |
| FTL | ferritin, light polypeptide | -0.0820424 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0661941 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.062435 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0603503 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0595991 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0573398 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0563358 |
| GPC6 | glypican 6 | -0.0560546 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0557273 |
| B2M | beta-2-microglobulin | -0.0546058 |
| S100A6 | S100 calcium binding protein A6 | -0.0504123 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0499167 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0497265 |
| TPM4 | tropomyosin 4 | -0.0489692 |
| GNAS | GNAS complex locus | -0.0483176 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0478304 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.047012 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0458159 |
| PLIN2 | perilipin 2 | -0.0450952 |
| FN1 | fibronectin 1 | -0.0433098 |
| RPL30 | ribosomal protein L30 | -0.0431617 |
| MAP1B | microtubule-associated protein 1B | -0.0423878 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0417831 |
| HLA-B | major histocompatibility complex, class I, B | -0.04106 |
| STK17A | serine/threonine kinase 17a | -0.040462 |
| DSTN | destrin (actin depolymerizing factor) | -0.0404201 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0399646 |
| HLA-E | major histocompatibility complex, class I, E | -0.0399379 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0398901 |
| RND3 | Rho family GTPase 3 | -0.0398809 |
| FRMD4A | FERM domain containing 4A | -0.0397811 |
| MTDH | metadherin | -0.0389259 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0387814 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0386562 |
| PLK2 | polo-like kinase 2 | -0.037802 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0375449 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.036737 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0360948 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0355588 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0348035 |
| OXR1 | oxidation resistance 1 | -0.0345952 |
| RPS5 | ribosomal protein S5 | -0.0333728 |
| SDCBP | syndecan binding protein (syntenin) | -0.0332608 |
| RPL12 | ribosomal protein L12 | -0.0330717 |
| CAVIN1 | caveolae associated protein 1 | -0.0322522 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0320821 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0319647 |
| SQLE | squalene epoxidase | -0.0319138 |
| ATP13A3 | ATPase type 13A3 | -0.0318917 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.031754 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0316899 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0315222 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0313112 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0312131 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0309543 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0306221 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0305614 |
| PALLD | palladin, cytoskeletal associated protein | -0.0305007 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0302632 |
| GDF15 | growth differentiation factor 15 | -0.0299752 |
| RAI14 | retinoic acid induced 14 | -0.0297575 |
| CALU | calumenin | -0.0297137 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0292923 |
| ACTG1 | actin gamma 1 | -0.0290698 |
| RPS8 | ribosomal protein S8 | -0.0290318 |
| TRAM1 | translocation associated membrane protein 1 | -0.0285267 |
| CTSD | cathepsin D | -0.028259 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0282069 |
| CADM1 | cell adhesion molecule 1 | -0.0278315 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0277202 |
| RPL19 | ribosomal protein L19 | -0.0276936 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0274394 |
| CD63 | CD63 molecule | -0.0272536 |
| RPL35A | ribosomal protein L35a | -0.0271426 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0268624 |
| RTN4 | reticulon 4 | -0.0268252 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0268191 |
| GOLGA4 | golgin A4 | -0.0267083 |
| MMP7 | matrix metallopeptidase 7 | -0.0263859 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0262621 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0259739 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0258204 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0258079 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0256164 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0255124 |
| TUBA1B | tubulin, alpha 1b | -0.0254756 |
| HLA-A | major histocompatibility complex, class I, A | -0.0254478 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0252226 |
| INSIG1 | insulin induced gene 1 | -0.0250516 |
| GPX3 | glutathione peroxidase 3 | -0.0249884 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.024887 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.024648 |
| S100A10 | S100 calcium binding protein A10 | -0.0245563 |
| LIMA1 | LIM domain and actin binding 1 | -0.0244293 |
