| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.118982 |
| DSPP | dentin sialophosphoprotein | 0.104568 |
| EGFR | epidermal growth factor receptor | 0.101607 |
| EZR | ezrin | 0.0953356 |
| LAMA4 | laminin, alpha 4 | 0.0927345 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0887977 |
| NDRG1 | N-myc downstream regulated 1 | 0.0881744 |
| CD44 | CD44 molecule (Indian blood group) | 0.0855237 |
| TXNRD1 | thioredoxin reductase 1 | 0.0841715 |
| TXNIP | thioredoxin interacting protein | 0.0836342 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.075049 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0738985 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0735539 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0724614 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0714616 |
| FAM107B | family with sequence similarity 107, member B | 0.0711311 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0706916 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0686032 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0639935 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0614749 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.061346 |
| SMAD3 | SMAD family member 3 | 0.0579215 |
| ENO1 | enolase 1, (alpha) | 0.0567825 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.055295 |
| TPM3 | tropomyosin 3 | 0.0517912 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0513188 |
| SGMS2 | sphingomyelin synthase 2 | 0.0500394 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0494466 |
| HMGA2 | high mobility group AT-hook 2 | 0.0480145 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0474691 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0470233 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0469358 |
| PKM | pyruvate kinase, muscle | 0.0469351 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0465793 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0462164 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0452402 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0440271 |
| CAPRIN2 | caprin family member 2 | 0.043742 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0430849 |
| GDA | guanine deaminase | 0.0428184 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0423975 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0397832 |
| ITGA6 | integrin, alpha 6 | 0.0396075 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0388088 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0385947 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0380699 |
| FMNL2 | formin-like 2 | 0.0380162 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0376466 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0372449 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0372107 |
| BMP6 | bone morphogenetic protein 6 | 0.0356879 |
| ASPH | aspartate beta-hydroxylase | 0.035541 |
| MYOF | myoferlin | 0.0354567 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0352797 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0350548 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0350221 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.034842 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0339607 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0339486 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0336901 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0336632 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0335105 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0332735 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0329405 |
| ABLIM1 | actin binding LIM protein 1 | 0.0325511 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0324252 |
| RPL41 | ribosomal protein L41 | 0.032391 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0322546 |
| SON | SON DNA binding protein | 0.0321254 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0320978 |
| TGM2 | transglutaminase 2 | 0.0319646 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.031944 |
| TLN1 | talin 1 | 0.0318392 |
| CALR | calreticulin | 0.0315615 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0312664 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0309469 |
| SDC4 | syndecan 4 | 0.030709 |
| AHR | aryl hydrocarbon receptor | 0.0298691 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0295381 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0293173 |
| KIAA0040 | KIAA0040 | 0.0292082 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0291769 |
| OPTN | optineurin | 0.0289602 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0285858 |
| FAM13A | family with sequence similarity 13, member A | 0.028251 |
| ANXA1 | annexin A1 | 0.0281951 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0280734 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0279744 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0279174 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0277426 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0276699 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0273599 |
| TPR | translocated promoter region, nuclear basket protein | 0.0270923 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0269538 |
| CANX | calnexin | 0.0269239 |
| TES | testin LIM domain protein | 0.0268424 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0266381 |
| ANO6 | anoctamin 6 | 0.0263363 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0263268 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.026279 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.192479 |
| TMSB10 | thymosin beta 10 | -0.172783 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.155925 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.142052 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.111153 |
| MUC17 | mucin 17, cell surface associated | -0.111127 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0965998 |
| HMGA1 | high mobility group AT-hook 1 | -0.0940744 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.089284 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0857375 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0835024 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0730751 |
| MXD1 | MAX dimerization protein 1 | -0.0699861 |
| LAMB3 | laminin, beta 3 | -0.0678352 |
| PARD3 | par-3 family cell polarity regulator | -0.0676402 |
| GNAS | GNAS complex locus | -0.067494 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0600701 |
| PRSS3 | protease, serine, 3 | -0.0579301 |
| NUP98 | nucleoporin 98kDa | -0.0564132 |
| EGR1 | early growth response 1 | -0.0561634 |
| SP100 | SP100 nuclear antigen | -0.056085 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0554488 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0553381 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0547664 |
| FOXO3 | forkhead box O3 | -0.05375 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0536671 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0534437 |
| TPM4 | tropomyosin 4 | -0.0528573 |
| S100A10 | S100 calcium binding protein A10 | -0.0525823 |
| FBXO11 | F-box protein 11 | -0.0509372 |
| FOSL1 | FOS-like antigen 1 | -0.0505957 |
| B2M | beta-2-microglobulin | -0.0500631 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0495842 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0495836 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0489566 |
| CLMP | CXADR-like membrane protein | -0.0481381 |
| MCU | mitochondrial calcium uniporter | -0.0469925 |
| RPL30 | ribosomal protein L30 | -0.0462805 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0459498 |
| RCOR1 | REST corepressor 1 | -0.0454977 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0454932 |
| VCL | vinculin | -0.0449366 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0447456 |
| LMO7 | LIM domain 7 | -0.0443722 |
| FOXO1 | forkhead box O1 | -0.0442817 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0440956 |
| HLA-E | major histocompatibility complex, class I, E | -0.0440378 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0436842 |
| ACTG1 | actin gamma 1 | -0.0436807 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0431401 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0419532 |
| TAOK3 | TAO kinase 3 | -0.0416738 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0416723 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0412548 |
| KLK10 | kallikrein-related peptidase 10 | -0.0401521 |
| PTMA | prothymosin, alpha | -0.0393069 |
| COG5 | component of oligomeric golgi complex 5 | -0.0391604 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0383443 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0380077 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0379458 |
| UBC | ubiquitin C | -0.0376073 |
| FTL | ferritin, light polypeptide | -0.0367692 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0365177 |
| ABHD3 | abhydrolase domain containing 3 | -0.0365055 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0354058 |
| RPS25 | ribosomal protein S25 | -0.0348781 |
| SAV1 | salvador family WW domain containing protein 1 | -0.0348327 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0346834 |
| RASAL2 | RAS protein activator like 2 | -0.0343258 |
| RHOA | ras homolog family member A | -0.0343205 |
| USP34 | ubiquitin specific peptidase 34 | -0.0339393 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.033646 |
| RHEB | Ras homolog enriched in brain | -0.0330334 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0327477 |
| RPLP0 | ribosomal protein, large, P0 | -0.0326988 |
| RPS24 | ribosomal protein S24 | -0.0323276 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0321595 |
| PGK1 | phosphoglycerate kinase 1 | -0.0320522 |
| ARF4 | ADP-ribosylation factor 4 | -0.0319857 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0319802 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0319449 |
| PLAT | plasminogen activator, tissue | -0.0314691 |
| RPS23 | ribosomal protein S23 | -0.0310147 |
| S100A6 | S100 calcium binding protein A6 | -0.0309596 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0308707 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0306587 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0303921 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0303916 |
| NPSR1 | neuropeptide S receptor 1 | -0.0302962 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0302588 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0300689 |
| SEM1 | SEM1 26S proteasome subunit | -0.0299523 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0299178 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0295512 |
| TMEM165 | transmembrane protein 165 | -0.0293084 |
| S100A4 | S100 calcium binding protein A4 | -0.0292941 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0292868 |
| OXSR1 | oxidative stress responsive 1 | -0.028876 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0287788 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0284768 |
