| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.21569 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.19736 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.145408 |
| ZNF608 | zinc finger protein 608 | 0.12236 |
| CENPF | centromere protein F, 350/400kDa | 0.0947333 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0898299 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0863948 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0853209 |
| VCL | vinculin | 0.0814635 |
| ENO1 | enolase 1, (alpha) | 0.0790919 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0716755 |
| MKI67 | marker of proliferation Ki-67 | 0.0693432 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.067817 |
| COL5A2 | collagen, type V, alpha 2 | 0.0653799 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0629334 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0619372 |
| RIGI | RNA sensor RIG-I | 0.0617377 |
| RPS3 | ribosomal protein S3 | 0.0585669 |
| RPL41 | ribosomal protein L41 | 0.0577547 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0573441 |
| RPLP1 | ribosomal protein, large, P1 | 0.0571998 |
| DST | dystonin | 0.0564957 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0555882 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0553369 |
| RPS12 | ribosomal protein S12 | 0.054786 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0525335 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0516864 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.050377 |
| PCM1 | pericentriolar material 1 | 0.0502195 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0494708 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0488823 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0475544 |
| TPR | translocated promoter region, nuclear basket protein | 0.0465599 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0460326 |
| RPS2 | ribosomal protein S2 | 0.0453318 |
| JMJD1C | jumonji domain containing 1C | 0.0448053 |
| RPL37A | ribosomal protein L37a | 0.0447946 |
| WLS | wntless Wnt ligand secretion mediator | 0.0446362 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0437783 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0413467 |
| WWOX | WW domain containing oxidoreductase | 0.0394531 |
| RPS8 | ribosomal protein S8 | 0.0392994 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0383341 |
| RPL4 | ribosomal protein L4 | 0.0381653 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0378565 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0377602 |
| ZNF644 | zinc finger protein 644 | 0.0371873 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0371501 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0369947 |
| RRM2 | ribonucleotide reductase M2 | 0.0364494 |
| ASPH | aspartate beta-hydroxylase | 0.0362796 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0359175 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.035543 |
| CDH18 | cadherin 18, type 2 | 0.0354641 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.034562 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0344539 |
| CCDC88A | coiled-coil domain containing 88A | 0.0343151 |
| RNF213 | ring finger protein 213 | 0.0339825 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.0337688 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0334491 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0333454 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0331792 |
| PKM | pyruvate kinase, muscle | 0.0328571 |
| GOLGB1 | golgin B1 | 0.0326561 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0323741 |
| MED13 | mediator complex subunit 13 | 0.0323067 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0319531 |
| CENPE | centromere protein E, 312kDa | 0.0319365 |
| HMGB2 | high mobility group box 2 | 0.0317486 |
| INTS6 | integrator complex subunit 6 | 0.031702 |
| RCC1 | regulator of chromosome condensation 1 | 0.0315213 |
| RPL35A | ribosomal protein L35a | 0.0314118 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0312327 |
| ANKRD36 | ankyrin repeat domain 36 | 0.030983 |
| CLTC | clathrin, heavy chain (Hc) | 0.03087 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0308354 |
| NFIB | nuclear factor I/B | 0.0307413 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0298292 |
| RPL26 | ribosomal protein L26 | 0.0298026 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0297226 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0296996 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0294504 |
| CALR | calreticulin | 0.0294381 |
| ATG10 | autophagy related 10 | 0.0293709 |
| CUX1 | cut-like homeobox 1 | 0.0291787 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0291584 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0286311 |
| ATP11A | ATPase, class VI, type 11A | 0.0286043 |
| RPL12 | ribosomal protein L12 | 0.0285717 |
| RPL34 | ribosomal protein L34 | 0.0284469 |
| TPM4 | tropomyosin 4 | 0.0283369 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0282797 |
| ATF4 | activating transcription factor 4 | 0.0280934 |
| PDS5A | PDS5 cohesin associated factor A | 0.0278054 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0277094 |
| SIK3 | SIK family kinase 3 | 0.0276774 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0276734 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0275886 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0275481 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0275275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.155586 |
| NPAS3 | neuronal PAS domain protein 3 | -0.150319 |
| RAD51B | RAD51 paralog B | -0.110144 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.10766 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0961563 |
| UBC | ubiquitin C | -0.0944098 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0942142 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0934067 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0865473 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0677144 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0647467 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0638217 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0622811 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0604063 |
| EFNA5 | ephrin-A5 | -0.0602624 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0569802 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0558795 |
| FOXO3 | forkhead box O3 | -0.0538974 |
| WDR45B | WD repeat domain 45B | -0.0504502 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0473375 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0456746 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0408795 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0405356 |
| ATRN | attractin | -0.0397465 |
| ZNF544 | zinc finger protein 544 | -0.0365764 |
| NUP58 | nucleoporin 58 | -0.0362332 |
| CADM2 | cell adhesion molecule 2 | -0.0350144 |
| EGR1 | early growth response 1 | -0.0334429 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0332229 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0331409 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0330649 |
| HHIP | hedgehog interacting protein | -0.0329455 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0327341 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0327125 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0325679 |
| FASN | fatty acid synthase | -0.0323579 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0319113 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.031346 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0309462 |
| ZFP64 | ZFP64 zinc finger protein | -0.0307216 |
| TOX | thymocyte selection-associated high mobility group box | -0.0301209 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0299751 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0299226 |
| SRPK2 | SRSF protein kinase 2 | -0.0293927 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.0290967 |
| PTCH1 | patched 1 | -0.0290301 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0286944 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0286024 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0281333 |
| EMP1 | epithelial membrane protein 1 | -0.0281181 |
| TENM2 | teneurin transmembrane protein 2 | -0.0269427 |
| CALU | calumenin | -0.0268231 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.026779 |
| TMEM117 | transmembrane protein 117 | -0.0267608 |
| KIAA1958 | KIAA1958 | -0.0266043 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0261998 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.026184 |
| GAB2 | GRB2-associated binding protein 2 | -0.0261304 |
| PTMA | prothymosin, alpha | -0.0258523 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.025834 |
| RYBP | RING1 and YY1 binding protein | -0.0257251 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | -0.0255205 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0251681 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0251381 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0249976 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0249087 |
| LRRC1 | leucine rich repeat containing 1 | -0.0248194 |
| TMEM123 | transmembrane protein 123 | -0.0242509 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0240596 |
| CCNY | cyclin Y | -0.023764 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0231828 |
| PARD3 | par-3 family cell polarity regulator | -0.0231701 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0229321 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0229221 |
| HMGA1 | high mobility group AT-hook 1 | -0.022864 |
| ZNF292 | zinc finger protein 292 | -0.022665 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0226425 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0225723 |
| RLF | rearranged L-myc fusion | -0.0225214 |
| SBF2 | SET binding factor 2 | -0.0224562 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0224081 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0223681 |
| FNBP1L | formin binding protein 1-like | -0.0222592 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.022073 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0218647 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0218538 |
| CCNI | cyclin I | -0.0217594 |
| HIP1 | huntingtin interacting protein 1 | -0.0217226 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0214747 |
| RPS15 | ribosomal protein S15 | -0.0211756 |
| FAM162A | family with sequence similarity 162, member A | -0.0211364 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0207554 |
| PUS7 | pseudouridylate synthase 7 (putative) | -0.020707 |
| DENND5B | DENN/MADD domain containing 5B | -0.0206402 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0204657 |
| ZNF652 | zinc finger protein 652 | -0.0203302 |
| TPD52 | tumor protein D52 | -0.0202987 |
| SNX3 | sorting nexin 3 | -0.0202876 |
| TENM3 | teneurin transmembrane protein 3 | -0.0202042 |
| SEPTIN11 | septin 11 | -0.0201394 |
