| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.162879 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.140836 |
| FNDC3B | fibronectin type III domain containing 3B | 0.139832 |
| ASPH | aspartate beta-hydroxylase | 0.136871 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.130557 |
| EFNA5 | ephrin-A5 | 0.119607 |
| MYOF | myoferlin | 0.0928594 |
| APOL1 | apolipoprotein L, 1 | 0.0900684 |
| LMO7 | LIM domain 7 | 0.0867685 |
| SMAD3 | SMAD family member 3 | 0.0782757 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0759455 |
| CANX | calnexin | 0.0752174 |
| BICC1 | BicC family RNA binding protein 1 | 0.0750666 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0746145 |
| APP | amyloid beta (A4) precursor protein | 0.0718483 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.069848 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0662649 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0617918 |
| ENO1 | enolase 1, (alpha) | 0.0617294 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.061329 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0595814 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0581485 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0565504 |
| MMP7 | matrix metallopeptidase 7 | 0.0540208 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0536848 |
| PHF3 | PHD finger protein 3 | 0.0523526 |
| FAM3C | family with sequence similarity 3, member C | 0.0519535 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0516615 |
| CD2AP | CD2-associated protein | 0.0499162 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0495535 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0486896 |
| JAK1 | Janus kinase 1 | 0.0466223 |
| EPAS1 | endothelial PAS domain protein 1 | 0.046525 |
| DST | dystonin | 0.0465051 |
| AREG | amphiregulin | 0.0464512 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.046241 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0460778 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0460432 |
| LDHA | lactate dehydrogenase A | 0.0456329 |
| SGMS2 | sphingomyelin synthase 2 | 0.0438868 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0437152 |
| SP100 | SP100 nuclear antigen | 0.0437122 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0436418 |
| KYNU | kynureninase | 0.0435356 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0433923 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0430688 |
| ACTN1 | actinin, alpha 1 | 0.041841 |
| PKM | pyruvate kinase, muscle | 0.0417973 |
| FUS | FUS RNA binding protein | 0.0412493 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0406687 |
| TGFB2 | transforming growth factor, beta 2 | 0.0402774 |
| DOCK5 | dedicator of cytokinesis 5 | 0.039895 |
| PRELID2 | PRELI domain containing 2 | 0.0395054 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0390153 |
| KIF13B | kinesin family member 13B | 0.0387377 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0380924 |
| CALR | calreticulin | 0.0379854 |
| MYO1E | myosin IE | 0.0379139 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0376663 |
| FAAH2 | fatty acid amide hydrolase 2 | 0.0375912 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0365979 |
| NRG3 | neuregulin 3 | 0.0357946 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0357543 |
| MX1 | MX dynamin-like GTPase 1 | 0.035408 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0352217 |
| KIAA1217 | KIAA1217 | 0.0351763 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0351533 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0350404 |
| CMIP | c-Maf inducing protein | 0.0350311 |
| TMSB4X | thymosin beta 4, X-linked | 0.0349777 |
| VMP1 | vacuole membrane protein 1 | 0.0346795 |
| LAMA4 | laminin, alpha 4 | 0.034193 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0341702 |
| TXNIP | thioredoxin interacting protein | 0.0341436 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0341176 |
| GOLGB1 | golgin B1 | 0.0338056 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0336419 |
| RNF213 | ring finger protein 213 | 0.0335344 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0331731 |
| FAM107B | family with sequence similarity 107, member B | 0.0330422 |
| STC2 | stanniocalcin 2 | 0.0329855 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0328792 |
| EHF | ets homologous factor | 0.0327938 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0327721 |
| TGM2 | transglutaminase 2 | 0.0324517 |
| RIGI | RNA sensor RIG-I | 0.0322826 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0320801 |
| RAD51B | RAD51 paralog B | 0.0320677 |
| SHROOM3 | shroom family member 3 | 0.0319611 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0311891 |
| INTS6 | integrator complex subunit 6 | 0.0311464 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.031112 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0310969 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0310428 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0307865 |
| KRT19 | keratin 19, type I | 0.0306715 |
| SMYD3 | SET and MYND domain containing 3 | 0.0306194 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0301614 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0300451 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0298456 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.125762 |
| DTNA | dystrobrevin, alpha | -0.0836932 |
| HMGA1 | high mobility group AT-hook 1 | -0.0691377 |
| PARD3 | par-3 family cell polarity regulator | -0.0648543 |
| RCOR1 | REST corepressor 1 | -0.0613893 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0580622 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0578646 |
| NDRG1 | N-myc downstream regulated 1 | -0.0573556 |
| AGRN | agrin | -0.0566099 |
| FLNB | filamin B, beta | -0.0541449 |
| TMEM165 | transmembrane protein 165 | -0.0538951 |
| LAMA5 | laminin, alpha 5 | -0.0487762 |
| TMSB10 | thymosin beta 10 | -0.0481242 |
| S100A6 | S100 calcium binding protein A6 | -0.0480397 |
| HLA-A | major histocompatibility complex, class I, A | -0.0467042 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0441774 |
| POTEF | POTE ankyrin domain family, member F | -0.0432223 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0425393 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0416423 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0416303 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.0409749 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0395193 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0389483 |
| GNAS | GNAS complex locus | -0.0388904 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0387425 |
| JUP | junction plakoglobin | -0.0373033 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.034943 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0348132 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0347664 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0340027 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0334619 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0332725 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.033031 |
| PTMA | prothymosin, alpha | -0.0324569 |
| WASF2 | WAS protein family, member 2 | -0.0322763 |
| FOXO3 | forkhead box O3 | -0.0318696 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0317188 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.030814 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0302898 |
| ACTG1 | actin gamma 1 | -0.0301807 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.029771 |
| PLAU | plasminogen activator, urokinase | -0.0297258 |
| HLA-B | major histocompatibility complex, class I, B | -0.0295891 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0293715 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0291276 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0289901 |
| KLF6 | Kruppel-like factor 6 | -0.028901 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0288873 |
| ITGA6 | integrin, alpha 6 | -0.0287954 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0286778 |
| RREB1 | ras responsive element binding protein 1 | -0.0284457 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0275402 |
| B2M | beta-2-microglobulin | -0.0273618 |
| FOSL1 | FOS-like antigen 1 | -0.0272553 |
| TAPBP | TAP binding protein (tapasin) | -0.0270944 |
| MXD1 | MAX dimerization protein 1 | -0.0264183 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0262377 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0260285 |
| HLA-E | major histocompatibility complex, class I, E | -0.0259539 |
| ITGB4 | integrin, beta 4 | -0.0258777 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0258736 |
| EGR1 | early growth response 1 | -0.0258689 |
| VIM | vimentin | -0.0258316 |
| LAMB3 | laminin, beta 3 | -0.0257443 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0254095 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0253793 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0253625 |
| RPS25 | ribosomal protein S25 | -0.0251563 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0250734 |
| ATP11B | ATPase, class VI, type 11B | -0.0250505 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0250287 |
| FA2H | fatty acid 2-hydroxylase | -0.025021 |
| RPS23 | ribosomal protein S23 | -0.0246041 |
| LAMC2 | laminin, gamma 2 | -0.0241269 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.023821 |
| MT1E | metallothionein 1E | -0.0237601 |
| CP | ceruloplasmin (ferroxidase) | -0.0235569 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0235242 |
| ZNF292 | zinc finger protein 292 | -0.0235174 |
| POM121 | POM121 transmembrane nucleoporin | -0.0233788 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0228133 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0227874 |
| JMJD1C | jumonji domain containing 1C | -0.0227262 |
| RTN4 | reticulon 4 | -0.0226775 |
| AXL | AXL receptor tyrosine kinase | -0.022508 |
| MAP1B | microtubule-associated protein 1B | -0.0224843 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0222364 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0221824 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0221598 |
| NCKAP5 | NCK-associated protein 5 | -0.0221273 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0219006 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0217703 |
| CCNY | cyclin Y | -0.0217306 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.021534 |
| TNS4 | tensin 4 | -0.0213826 |
| INSIG1 | insulin induced gene 1 | -0.021349 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0213227 |
| FDPS | farnesyl diphosphate synthase | -0.0213142 |
| TLK2 | tousled-like kinase 2 | -0.0210566 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0210557 |