Fusidic acid_CHP-212 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Fusidic acid perturbation in CHP-212 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Fusidic acid_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NALF1 NALCN channel auxiliary factor 1 0.0746839
TPST1 tyrosylprotein sulfotransferase 1 0.074256
EXT1 exostosin glycosyltransferase 1 0.0640433
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.0636391
TLE4 transducin-like enhancer of split 4 0.0627613
DST dystonin 0.0621027
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.0618873
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0606856
PTPRK protein tyrosine phosphatase, receptor type, K 0.0593402
PTPRD protein tyrosine phosphatase, receptor type, D 0.0587064
LINGO2 leucine rich repeat and Ig domain containing 2 0.0560454
TRIO trio Rho guanine nucleotide exchange factor 0.0553271
LSAMP limbic system-associated membrane protein 0.0550418
VMP1 vacuole membrane protein 1 0.0545418
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 0.0537647
PSD3 pleckstrin and Sec7 domain containing 3 0.0497158
PDE10A phosphodiesterase 10A 0.0486365
FAM107B family with sequence similarity 107, member B 0.0484116
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.0475165
ANTXR1 anthrax toxin receptor 1 0.046724
MEIS2 Meis homeobox 2 0.045567
SIK2 salt-inducible kinase 2 0.0449195
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0436269
THSD4 thrombospondin, type I, domain containing 4 0.0430547
SLIT2 slit homolog 2 (Drosophila) 0.0419973
MACF1 microtubule-actin crosslinking factor 1 0.0417598
RNF213 ring finger protein 213 0.0412724
KLHL13 kelch-like family member 13 0.0398237
PLPP1 phospholipid phosphatase 1 0.0396312
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0383264
CEMIP cell migration inducing protein, hyaluronan binding 0.0373415
NPAS2 neuronal PAS domain protein 2 0.0368653
CRH corticotropin releasing hormone 0.0361906
COL4A5 collagen, type IV, alpha 5 0.035553
MSI2 musashi RNA-binding protein 2 0.0350536
PTPRE protein tyrosine phosphatase, receptor type, E 0.0346461
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.034625
BPTF bromodomain PHD finger transcription factor 0.0339593
DGKH diacylglycerol kinase, eta 0.0337814
TENM4 teneurin transmembrane protein 4 0.0334904
SLC38A2 solute carrier family 38, member 2 0.033441
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0329437
SEPTIN9 septin 9 0.0325662
FMN1 formin 1 0.0322726
MYH9 myosin, heavy chain 9, non-muscle 0.0320315
PRKCA protein kinase C, alpha 0.0314959
BICD1 bicaudal D homolog 1 (Drosophila) 0.0312472
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0307837
CDH10 cadherin 10, type 2 (T2-cadherin) 0.0299956
PLAT plasminogen activator, tissue 0.0298906
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0298698
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.029433
ITPRID2 ITPR interacting domain containing 2 0.0291634
ASPH aspartate beta-hydroxylase 0.0289758
GLCCI1 glucocorticoid induced 1 0.0284364
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.028125
NF1 neurofibromin 1 0.0280301
UNC5C unc-5 homolog C (C. elegans) 0.0277795
PDE4D phosphodiesterase 4D, cAMP-specific 0.0276571
ZFC3H1 zinc finger, C3H1-type containing 0.0276076
MYO6 myosin VI 0.0275535
SETBP1 SET binding protein 1 0.0274522
ENO1 enolase 1, (alpha) 0.0274238
PTEN phosphatase and tensin homolog 0.0271339
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.0270881
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0270153
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.026927
ACTN1 actinin, alpha 1 0.0266179
SLITRK6 SLIT and NTRK-like family, member 6 0.0265933
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0263393
ARHGAP9 Rho GTPase activating protein 9 0.0262759
AUTS2 autism susceptibility candidate 2 0.0261493
EXOC4 exocyst complex component 4 0.0257396
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0256293
GAB2 GRB2-associated binding protein 2 0.025612
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.0250077
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0247591
ADARB1 adenosine deaminase, RNA-specific, B1 0.0247403
ANGPT1 angiopoietin 1 0.0245737
SMYD3 SET and MYND domain containing 3 0.0245435
DNM3 dynamin 3 0.0245321
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.0245035
PACS1 phosphofurin acidic cluster sorting protein 1 0.0240929
ATXN1 ataxin 1 0.0240343
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0240026
ZSWIM6 zinc finger, SWIM-type containing 6 0.0237963
PCBP3 poly(rC) binding protein 3 0.0235706
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.023522
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.0232463
SDK1 sidekick cell adhesion molecule 1 0.0229809
BCAS3 breast carcinoma amplified sequence 3 0.0229066
LIMCH1 LIM and calponin homology domains 1 0.0227998
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0226821
GLI3 GLI family zinc finger 3 0.0226606
FNDC3A fibronectin type III domain containing 3A 0.0224887
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0221268
APP amyloid beta (A4) precursor protein 0.0218527
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.0215286
HMBOX1 homeobox containing 1 0.0214526
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0213545

decreased expression

Symbol Name Standardized Value
IGF2 insulin-like growth factor 2 -0.21189
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.169594
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -0.116757
PTMA prothymosin, alpha -0.0921185
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0628851
VIM vimentin -0.0584168
TPT1 tumor protein, translationally-controlled 1 -0.0557627
RPL38 ribosomal protein L38 -0.0555436
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0547336
COL1A1 collagen, type I, alpha 1 -0.0528877
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0423756
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0417135
ACTG1 actin gamma 1 -0.0416272
RPLP1 ribosomal protein, large, P1 -0.0372214
RPL19 ribosomal protein L19 -0.0362384
RPS24 ribosomal protein S24 -0.0359157
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0336947
CCDC47 coiled-coil domain containing 47 -0.0317198
WDR45B WD repeat domain 45B -0.0305897
HAND2 heart and neural crest derivatives expressed 2 -0.0294235
RAB1A RAB1A, member RAS oncogene family -0.0285534
FKBP10 FK506 binding protein 10, 65 kDa -0.0281801
RPL23 ribosomal protein L23 -0.0270578
NAP1L1 nucleosome assembly protein 1-like 1 -0.026641
NME2 NME/NM23 nucleoside diphosphate kinase 2 -0.0260863
H3-3B H3.3 histone B -0.0260277
SEPTIN2 septin 2 -0.0254163
RPL34 ribosomal protein L34 -0.0249929
NRG1 neuregulin 1 -0.0249357
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0248378
NPEPPS aminopeptidase puromycin sensitive -0.024513
KPNB1 karyopherin (importin) beta 1 -0.0242039
RPL32 ribosomal protein L32 -0.0241936
EIF1 eukaryotic translation initiation factor 1 -0.0235224
FNBP1 formin binding protein 1 -0.0227089
KDM3A lysine (K)-specific demethylase 3A -0.0226886
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0221549
CCND1 cyclin D1 -0.0219713
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0218505
IARS1 isoleucyl-tRNA synthetase 1 -0.0218418
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0216822
RPLP0 ribosomal protein, large, P0 -0.0211949
PNISR PNN-interacting serine/arginine-rich protein -0.0210561
PRR11 proline rich 11 -0.0208592
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0207222
LMNA lamin A/C -0.0204479
GOLGA4 golgin A4 -0.0199339
MARCHF6 membrane associated ring-CH-type finger 6 -0.019915
GARS1 glycyl-tRNA synthetase 1 -0.0198361
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.0188968
ANXA2 annexin A2 -0.0187232
RPS23 ribosomal protein S23 -0.0186621
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0185621
AHNAK AHNAK nucleoprotein -0.0184745
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0184081
S100A6 S100 calcium binding protein A6 -0.0183885
RPS27A ribosomal protein S27a -0.0181815
RPL36A ribosomal protein L36a -0.0180838
EIF3A eukaryotic translation initiation factor 3, subunit A -0.0180141
PCNX4 pecanex 4 -0.017965
SEC63 SEC63 homolog (S. cerevisiae) -0.0178622
SCLT1 sodium channel and clathrin linker 1 -0.0177418
RPL7A ribosomal protein L7a -0.0176873
MBD5 methyl-CpG binding domain protein 5 -0.0171962
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0171878
HDLBP high density lipoprotein binding protein -0.0171142
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -0.0169479
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.0168615
TMEM123 transmembrane protein 123 -0.0167444
PDIA3 protein disulfide isomerase family A, member 3 -0.0165988
HMGB1 high mobility group box 1 -0.0162287
PHIP pleckstrin homology domain interacting protein -0.0161725
RPS16 ribosomal protein S16 -0.016108
RPS25 ribosomal protein S25 -0.0160503
RPL9 ribosomal protein L9 -0.0160289
RFC3 replication factor C (activator 1) 3, 38kDa -0.0157935
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0157529
GLG1 golgi glycoprotein 1 -0.0156892
RPL7 ribosomal protein L7 -0.0156463
ATP5F1B ATP synthase F1 subunit beta -0.0156148
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0155989
RPS15 ribosomal protein S15 -0.0155483
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.015405
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0153882
RPL30 ribosomal protein L30 -0.0153608
RPS5 ribosomal protein S5 -0.0152796
AKAP10 A kinase (PRKA) anchor protein 10 -0.0151562
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0148876
ACBD3 acyl-CoA binding domain containing 3 -0.0148667
UBE2O ubiquitin-conjugating enzyme E2O -0.0146938
ANKRD10 ankyrin repeat domain 10 -0.0146905
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.0146526
ARF1 ADP-ribosylation factor 1 -0.0146343
DSCAM Down syndrome cell adhesion molecule -0.0145504
SMC4 structural maintenance of chromosomes 4 -0.014509
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0144875
CENPF centromere protein F, 350/400kDa -0.0144719
RBMX RNA binding motif protein, X-linked -0.0144571
RAB7A RAB7A, member RAS oncogene family -0.0143969
LPIN1 lipin 1 -0.0143215