| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.358853 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.151141 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.147627 |
| SMAD3 | SMAD family member 3 | 0.132126 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.131822 |
| EXT1 | exostosin glycosyltransferase 1 | 0.10739 |
| RUNX1 | runt-related transcription factor 1 | 0.1036 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0973378 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.093397 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0832135 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0713668 |
| SQSTM1 | sequestosome 1 | 0.0690127 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0654902 |
| ITGA6 | integrin, alpha 6 | 0.0648391 |
| KYNU | kynureninase | 0.0641656 |
| DST | dystonin | 0.0629335 |
| MSI2 | musashi RNA-binding protein 2 | 0.0598364 |
| EFNB2 | ephrin-B2 | 0.058648 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0524298 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0523483 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0510347 |
| CALR | calreticulin | 0.0506129 |
| FNIP2 | folliculin interacting protein 2 | 0.0490427 |
| ABHD2 | abhydrolase domain containing 2 | 0.048238 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.047388 |
| CTBP2 | C-terminal binding protein 2 | 0.0456801 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0455819 |
| PADI1 | peptidyl arginine deiminase, type I | 0.04377 |
| TOX3 | TOX high mobility group box family member 3 | 0.0434303 |
| DSPP | dentin sialophosphoprotein | 0.042902 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0424292 |
| MLPH | melanophilin | 0.0424053 |
| TRIM2 | tripartite motif containing 2 | 0.0416035 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0415296 |
| PRELID2 | PRELI domain containing 2 | 0.0413155 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0412877 |
| KIAA1217 | KIAA1217 | 0.0405577 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.040502 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.040397 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0399604 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0390465 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0387876 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0382793 |
| SLK | STE20-like kinase | 0.0382491 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.038216 |
| HKDC1 | hexokinase domain containing 1 | 0.0381648 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0381101 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0376161 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0371147 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0368769 |
| EHF | ets homologous factor | 0.0364955 |
| ASPH | aspartate beta-hydroxylase | 0.0363515 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0359905 |
| DUSP16 | dual specificity phosphatase 16 | 0.0356207 |
| YAP1 | Yes-associated protein 1 | 0.0351177 |
| MYO1E | myosin IE | 0.0350944 |
| SPAG9 | sperm associated antigen 9 | 0.0346696 |
| MED13 | mediator complex subunit 13 | 0.0344678 |
| RRBP1 | ribosome binding protein 1 | 0.034389 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0338541 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0332993 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0331821 |
| LAMB3 | laminin, beta 3 | 0.0330455 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0328673 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0324793 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.032479 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0323562 |
| NEBL | nebulette | 0.0323234 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0322119 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0321439 |
| RNF43 | ring finger protein 43 | 0.0320037 |
| CANX | calnexin | 0.0314853 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0313885 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0312009 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0308328 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0299172 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0297584 |
| EPHB2 | EPH receptor B2 | 0.0295406 |
| ENO1 | enolase 1, (alpha) | 0.0294761 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0293137 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.02904 |
| SDC4 | syndecan 4 | 0.0284434 |
| USP54 | ubiquitin specific peptidase 54 | 0.0279762 |
| TC2N | tandem C2 domains, nuclear | 0.027786 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0276148 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0275146 |
| TPR | translocated promoter region, nuclear basket protein | 0.0271754 |
| PDZD8 | PDZ domain containing 8 | 0.0270982 |
| ABLIM1 | actin binding LIM protein 1 | 0.0270432 |
| OGA | O-GlcNAcase | 0.0268045 |
| H1-0 | H1.0 linker histone | 0.0265927 |
| HYOU1 | hypoxia up-regulated 1 | 0.026506 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0264188 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0262024 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.02607 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0258499 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0257839 |
| MUC13 | mucin 13, cell surface associated | 0.0255213 |
| HDAC4 | histone deacetylase 4 | 0.0253531 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0251036 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | -0.12098 |
| LYZ | lysozyme | -0.11417 |
| VCL | vinculin | -0.109437 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0905588 |
| PHF3 | PHD finger protein 3 | -0.0858775 |
| NPSR1 | neuropeptide S receptor 1 | -0.0734364 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.071292 |
| B2M | beta-2-microglobulin | -0.0655864 |
| SP100 | SP100 nuclear antigen | -0.065586 |
| PLSCR2 | phospholipid scramblase 2 | -0.0639315 |
| RIGI | RNA sensor RIG-I | -0.058802 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0578299 |
| XAF1 | XIAP associated factor 1 | -0.0549725 |
| PLSCR1 | phospholipid scramblase 1 | -0.054417 |
| ANXA2 | annexin A2 | -0.0532754 |
| TNS4 | tensin 4 | -0.0527293 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.050286 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0493951 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0487892 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0464815 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0451042 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0447149 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.042997 |
| MX1 | MX dynamin-like GTPase 1 | -0.0429748 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0429656 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0426673 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0417851 |
| MX2 | MX dynamin-like GTPase 2 | -0.0417421 |
| POU2F2 | POU class 2 homeobox 2 | -0.0400987 |
| TXNIP | thioredoxin interacting protein | -0.0400036 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0398189 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.038342 |
| ACTG1 | actin gamma 1 | -0.0380105 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0377994 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0372925 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0369802 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.036223 |
| NCKAP5 | NCK-associated protein 5 | -0.0361046 |
| RPS6 | ribosomal protein S6 | -0.035758 |
| ZNF609 | zinc finger protein 609 | -0.0355579 |
| PMP22 | peripheral myelin protein 22 | -0.0353342 |
| MCL1 | myeloid cell leukemia 1 | -0.0352466 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0347761 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.034211 |
| PTMA | prothymosin, alpha | -0.0341862 |
| MAP7 | microtubule-associated protein 7 | -0.0333387 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0330339 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0326228 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | -0.0301218 |
| NDRG1 | N-myc downstream regulated 1 | -0.030022 |
| AHI1 | Abelson helper integration site 1 | -0.029942 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0298343 |
| INTS6 | integrator complex subunit 6 | -0.0284956 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0284343 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0283077 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0275203 |
| LAP3 | leucine aminopeptidase 3 | -0.0265607 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0264948 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0258559 |
| GPATCH8 | G patch domain containing 8 | -0.0257499 |
| FBXO39 | F-box protein 39 | -0.0253528 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0253283 |
| TRIM25 | tripartite motif containing 25 | -0.0252696 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0250729 |
| TRIM56 | tripartite motif containing 56 | -0.0247665 |
| FOSL1 | FOS-like antigen 1 | -0.024529 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0244984 |
| ADAR | adenosine deaminase, RNA-specific | -0.0243515 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0241988 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0238947 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0237455 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0236776 |
| ZNF207 | zinc finger protein 207 | -0.0231838 |
| AREG | amphiregulin | -0.0228644 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0228325 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.0225038 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0221241 |
| THOC2 | THO complex 2 | -0.0220259 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0219218 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0217853 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0216457 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0215703 |
| RAD51B | RAD51 paralog B | -0.021192 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.0210854 |
| EPCAM | epithelial cell adhesion molecule | -0.0210185 |
| GOLGB1 | golgin B1 | -0.0210038 |
| RPS8 | ribosomal protein S8 | -0.0209578 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0208622 |
| CCND3 | cyclin D3 | -0.0208481 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0208384 |
| TNPO3 | transportin 3 | -0.0207557 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0206995 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0206958 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0205798 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0204907 |
| HSH2D | hematopoietic SH2 domain containing | -0.0202117 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0202104 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0200688 |
| APOL6 | apolipoprotein L, 6 | -0.0200225 |
| IRF9 | interferon regulatory factor 9 | -0.0199707 |