| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.171578 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.120907 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.105418 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.101549 |
| EZR | ezrin | 0.0954256 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0887968 |
| PRELID2 | PRELI domain containing 2 | 0.0873215 |
| ENO1 | enolase 1, (alpha) | 0.0825651 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0646491 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0605231 |
| ZNF638 | zinc finger protein 638 | 0.0576429 |
| ASPH | aspartate beta-hydroxylase | 0.0537867 |
| TXNRD1 | thioredoxin reductase 1 | 0.0524979 |
| HELZ | helicase with zinc finger | 0.0510757 |
| PCM1 | pericentriolar material 1 | 0.0506422 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0501634 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0497529 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0492686 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.048982 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0476229 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0472968 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0472114 |
| POTEF | POTE ankyrin domain family, member F | 0.0468563 |
| CALR | calreticulin | 0.046788 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0454045 |
| SMYD3 | SET and MYND domain containing 3 | 0.0452576 |
| ATXN1 | ataxin 1 | 0.0437353 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0436083 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0435757 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.042442 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0421638 |
| GOLGB1 | golgin B1 | 0.0419953 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0415613 |
| TPM3 | tropomyosin 3 | 0.0415237 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0413258 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0401709 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0398699 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0398423 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0394301 |
| PCBP2 | poly(rC) binding protein 2 | 0.0388599 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0385999 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.038425 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.038401 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0383346 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0382706 |
| ZNF292 | zinc finger protein 292 | 0.0377349 |
| BBX | bobby sox homolog (Drosophila) | 0.0371748 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0371186 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0370125 |
| HYOU1 | hypoxia up-regulated 1 | 0.036605 |
| DST | dystonin | 0.0365941 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0362321 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0360271 |
| NEBL | nebulette | 0.0358161 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0357703 |
| MT2A | metallothionein 2A | 0.0356616 |
| TMF1 | TATA element modulatory factor 1 | 0.0349072 |
| COPA | coatomer protein complex, subunit alpha | 0.0346141 |
| AFDN | afadin, adherens junction formation factor | 0.0343702 |
| TENM3 | teneurin transmembrane protein 3 | 0.0343558 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.034192 |
| VMP1 | vacuole membrane protein 1 | 0.0340354 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0339953 |
| SPAG9 | sperm associated antigen 9 | 0.0335531 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0334779 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0333648 |
| UTRN | utrophin | 0.0333287 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0328867 |
| SON | SON DNA binding protein | 0.0327969 |
| YEATS2 | YEATS domain containing 2 | 0.0326411 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.032514 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0324778 |
| DSPP | dentin sialophosphoprotein | 0.0324289 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0322425 |
| EXOC6B | exocyst complex component 6B | 0.0320135 |
| YTHDC1 | YTH domain containing 1 | 0.0319226 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0314735 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0313653 |
| TXNIP | thioredoxin interacting protein | 0.031337 |
| ANKRD12 | ankyrin repeat domain 12 | 0.030877 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0304023 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0303955 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.030345 |
| TLN1 | talin 1 | 0.0300551 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0300326 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0299178 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0296639 |
| WWC2 | WW and C2 domain containing 2 | 0.0294412 |
| TJP1 | tight junction protein 1 | 0.0293352 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0293305 |
| RPL3 | ribosomal protein L3 | 0.0288855 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0287772 |
| CANX | calnexin | 0.0287193 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0286368 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0284437 |
| MACROD2 | MACRO domain containing 2 | 0.0280714 |
| USP34 | ubiquitin specific peptidase 34 | 0.0280485 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0278029 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0274731 |
| PLEC | plectin | 0.027345 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195352 |
| AHNAK | AHNAK nucleoprotein | -0.194749 |
| NDRG1 | N-myc downstream regulated 1 | -0.180924 |
| PTMA | prothymosin, alpha | -0.171047 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0871832 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0845913 |
| SERINC5 | serine incorporator 5 | -0.0759126 |
| RPS6 | ribosomal protein S6 | -0.0597481 |
| RPS24 | ribosomal protein S24 | -0.0588117 |
| EGR1 | early growth response 1 | -0.0514823 |
| FAT1 | FAT atypical cadherin 1 | -0.0474368 |
| RPS8 | ribosomal protein S8 | -0.0469401 |
| TPM4 | tropomyosin 4 | -0.046733 |
| RPS25 | ribosomal protein S25 | -0.0461556 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0461436 |
| FDPS | farnesyl diphosphate synthase | -0.045654 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0450628 |
| CCND1 | cyclin D1 | -0.0445482 |
| KRT18 | keratin 18, type I | -0.0443846 |
| RACK1 | receptor for activated C kinase 1 | -0.0418771 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0408073 |
| RPS15 | ribosomal protein S15 | -0.0405826 |
| TMSB10 | thymosin beta 10 | -0.0396417 |
| S100A6 | S100 calcium binding protein A6 | -0.0390232 |
| TMEM123 | transmembrane protein 123 | -0.0383459 |
| ACTG1 | actin gamma 1 | -0.0378152 |
| S100A10 | S100 calcium binding protein A10 | -0.0371165 |
| RPL7A | ribosomal protein L7a | -0.0357195 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0351592 |
| CADPS | Ca++-dependent secretion activator | -0.0343407 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0343398 |
| UBC | ubiquitin C | -0.0340687 |
| EREG | epiregulin | -0.033426 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0327093 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0324546 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0319499 |
| ITGB4 | integrin, beta 4 | -0.0316708 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0313692 |
| MEF2A | myocyte enhancer factor 2A | -0.0307027 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0297943 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.029755 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0293089 |
| GNAS | GNAS complex locus | -0.0291334 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0288523 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0287921 |
| RPL31 | ribosomal protein L31 | -0.0285208 |
| TUBA1B | tubulin, alpha 1b | -0.028518 |
| RPL34 | ribosomal protein L34 | -0.0272507 |
| HMGA1 | high mobility group AT-hook 1 | -0.026483 |
| PGK1 | phosphoglycerate kinase 1 | -0.0264745 |
| RPS13 | ribosomal protein S13 | -0.0259754 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.025962 |
| VCL | vinculin | -0.0258477 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0258154 |
| RPL11 | ribosomal protein L11 | -0.0256734 |
| PALD1 | phosphatase domain containing, paladin 1 | -0.0249574 |
| SNX14 | sorting nexin 14 | -0.024936 |
| RPS23 | ribosomal protein S23 | -0.0248653 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0247915 |
| EPCAM | epithelial cell adhesion molecule | -0.0246347 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0245785 |
| RPLP0 | ribosomal protein, large, P0 | -0.0245667 |
| TBC1D22A | TBC1 domain family, member 22A | -0.024348 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0243305 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0240919 |
| RPL8 | ribosomal protein L8 | -0.0240638 |
| RPL27A | ribosomal protein L27a | -0.023935 |
| RPL38 | ribosomal protein L38 | -0.0239052 |
| RPL35A | ribosomal protein L35a | -0.0238521 |
| HMGA2 | high mobility group AT-hook 2 | -0.0238362 |
| RPS16 | ribosomal protein S16 | -0.0237454 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0233249 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0232335 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.0231337 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0231062 |
| RPL36A | ribosomal protein L36a | -0.0230908 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0230369 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0229994 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | -0.0224595 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0221761 |
| RPS10 | ribosomal protein S10 | -0.0221743 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0220023 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0219647 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0218982 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0218771 |
| RPLP1 | ribosomal protein, large, P1 | -0.021844 |
| RPL23 | ribosomal protein L23 | -0.0218365 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0217063 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0216628 |
| ADD1 | adducin 1 (alpha) | -0.0216612 |
| RPS5 | ribosomal protein S5 | -0.0216231 |
| RPL13A | ribosomal protein L13a | -0.0216188 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0215957 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0214662 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0213914 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0212452 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0212346 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0210328 |
| LRRC23 | leucine rich repeat containing 23 | -0.0209606 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0209458 |
