| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRELID2 | PRELI domain containing 2 | 0.196231 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.183728 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.127175 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.126685 |
| ENO1 | enolase 1, (alpha) | 0.124854 |
| ASPH | aspartate beta-hydroxylase | 0.12028 |
| PKM | pyruvate kinase, muscle | 0.0970995 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0960496 |
| CALR | calreticulin | 0.0916242 |
| CANX | calnexin | 0.0889964 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0857956 |
| ECT2 | epithelial cell transforming 2 | 0.0839882 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0817085 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0781986 |
| INTS6 | integrator complex subunit 6 | 0.075381 |
| EZR | ezrin | 0.0653853 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0649771 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0629301 |
| GOLGB1 | golgin B1 | 0.0626066 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0597109 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0561832 |
| DIAPH3 | diaphanous-related formin 3 | 0.0561647 |
| APP | amyloid beta (A4) precursor protein | 0.0549099 |
| VMP1 | vacuole membrane protein 1 | 0.054805 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0539833 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0508208 |
| SPAG9 | sperm associated antigen 9 | 0.0504739 |
| ANXA1 | annexin A1 | 0.0497874 |
| FNIP1 | folliculin interacting protein 1 | 0.0488869 |
| VCL | vinculin | 0.0477176 |
| LDHA | lactate dehydrogenase A | 0.0473161 |
| SMAD3 | SMAD family member 3 | 0.0466168 |
| DSPP | dentin sialophosphoprotein | 0.0453795 |
| TJP1 | tight junction protein 1 | 0.043796 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0432991 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0430379 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0421177 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0417523 |
| RUNX1 | runt-related transcription factor 1 | 0.0414699 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0408597 |
| MYO1D | myosin ID | 0.0408574 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0406785 |
| ZNF638 | zinc finger protein 638 | 0.0402844 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0401307 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0393016 |
| BBX | bobby sox homolog (Drosophila) | 0.0388323 |
| FNDC3B | fibronectin type III domain containing 3B | 0.037804 |
| CLTC | clathrin, heavy chain (Hc) | 0.0364176 |
| SEPTIN9 | septin 9 | 0.0363526 |
| EXOC4 | exocyst complex component 4 | 0.0360371 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0349703 |
| YEATS2 | YEATS domain containing 2 | 0.0348597 |
| COG6 | component of oligomeric golgi complex 6 | 0.03465 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0344793 |
| KIAA1328 | KIAA1328 | 0.0344099 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0341489 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0337566 |
| GOLGA4 | golgin A4 | 0.0335395 |
| TMF1 | TATA element modulatory factor 1 | 0.0334984 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0334491 |
| HYOU1 | hypoxia up-regulated 1 | 0.0331503 |
| ANO6 | anoctamin 6 | 0.0326248 |
| WWOX | WW domain containing oxidoreductase | 0.0321753 |
| ACTN1 | actinin, alpha 1 | 0.0320706 |
| RAD51B | RAD51 paralog B | 0.0319351 |
| RPL41 | ribosomal protein L41 | 0.0316363 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0315242 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0315229 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0312773 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0312701 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0310651 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0310529 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0307622 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0306043 |
| BPTF | bromodomain PHD finger transcription factor | 0.0305965 |
| METTL15 | methyltransferase like 15 | 0.0304122 |
| AFDN | afadin, adherens junction formation factor | 0.0303911 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0300062 |
| SETX | senataxin | 0.0299221 |
| INSIG2 | insulin induced gene 2 | 0.0299125 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0296599 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0294747 |
| PGM3 | phosphoglucomutase 3 | 0.0294661 |
| SCFD1 | sec1 family domain containing 1 | 0.0294365 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0290097 |
| MT2A | metallothionein 2A | 0.028863 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0288456 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0286947 |
| NUP58 | nucleoporin 58 | 0.02858 |
| TPR | translocated promoter region, nuclear basket protein | 0.028309 |
| MACROD2 | MACRO domain containing 2 | 0.0282451 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0279293 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0278058 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0275516 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0274978 |
| ANLN | anillin, actin binding protein | 0.0272073 |
| ACTN4 | actinin, alpha 4 | 0.0271896 |
| CPNE1 | copine I | 0.0271199 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0270054 |
| CDK13 | cyclin-dependent kinase 13 | 0.0268202 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.137364 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0848941 |
| PTMA | prothymosin, alpha | -0.0774671 |
| ACTG1 | actin gamma 1 | -0.0732215 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0532791 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.052899 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0522288 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0519716 |
| HMGA1 | high mobility group AT-hook 1 | -0.0508689 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0502104 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0449098 |
| MATR3 | matrin 3 | -0.044236 |
| AHNAK | AHNAK nucleoprotein | -0.0434662 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0415505 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0413347 |
| RPL28 | ribosomal protein L28 | -0.0380757 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0378018 |
| NF1 | neurofibromin 1 | -0.0376899 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0373513 |
| TCERG1 | transcription elongation regulator 1 | -0.0372042 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0371809 |
| ZNF292 | zinc finger protein 292 | -0.0371158 |
| CCND1 | cyclin D1 | -0.0369152 |
| RPL31 | ribosomal protein L31 | -0.0366026 |
| RPLP2 | ribosomal protein, large, P2 | -0.0349767 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0349458 |
| PAX8 | paired box 8 | -0.034816 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0346928 |
| PARD3 | par-3 family cell polarity regulator | -0.0344872 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0342255 |
| SSH2 | slingshot protein phosphatase 2 | -0.034188 |
| PCED1B | PC-esterase domain containing 1B | -0.0337185 |
| TMSB10 | thymosin beta 10 | -0.0336927 |
| RPL32 | ribosomal protein L32 | -0.0335578 |
| PGK1 | phosphoglycerate kinase 1 | -0.0327334 |
| ANKRD28 | ankyrin repeat domain 28 | -0.032616 |
| RPS19 | ribosomal protein S19 | -0.0325473 |
| RPS25 | ribosomal protein S25 | -0.0325001 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0323277 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0318979 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0318868 |
| RPS6 | ribosomal protein S6 | -0.0315052 |
| GNAS | GNAS complex locus | -0.0314892 |
| S100A6 | S100 calcium binding protein A6 | -0.0312773 |
| MAP4 | microtubule-associated protein 4 | -0.0312263 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0311709 |
| ANXA2 | annexin A2 | -0.0311687 |
| RPS29 | ribosomal protein S29 | -0.0301955 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0294191 |
| RPS24 | ribosomal protein S24 | -0.0294061 |
| MKI67 | marker of proliferation Ki-67 | -0.0292198 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0291782 |
| SETD5 | SET domain containing 5 | -0.0289734 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.028909 |
| RPL5 | ribosomal protein L5 | -0.028751 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0287381 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0283763 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0280573 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0278515 |
| ZNF207 | zinc finger protein 207 | -0.0278025 |
| RPL7A | ribosomal protein L7a | -0.0277876 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0272576 |
| ZFR | zinc finger RNA binding protein | -0.0271865 |
| SBF2 | SET binding factor 2 | -0.0271551 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0271448 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0271318 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0269673 |
| S100A4 | S100 calcium binding protein A4 | -0.0269511 |
| WWC1 | WW and C2 domain containing 1 | -0.0269286 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.026709 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0264035 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0263973 |
| FIGN | fidgetin | -0.026219 |
| RPL38 | ribosomal protein L38 | -0.0258982 |
| RPS23 | ribosomal protein S23 | -0.0257813 |
| RFX7 | regulatory factor X, 7 | -0.0257692 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0256959 |
| RBM25 | RNA binding motif protein 25 | -0.0252684 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0252023 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0251842 |
| SEPTIN10 | septin 10 | -0.0251396 |
| CDC27 | cell division cycle 27 | -0.0250699 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0249489 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0249122 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0248885 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | -0.0248734 |
| RPS14 | ribosomal protein S14 | -0.0247679 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0247552 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0244252 |
| ATG7 | autophagy related 7 | -0.0243486 |
| TKT | transketolase | -0.0243474 |
| RPS16 | ribosomal protein S16 | -0.0241896 |
| S100A9 | S100 calcium binding protein A9 | -0.023758 |
| RACK1 | receptor for activated C kinase 1 | -0.0237312 |
| IER3 | immediate early response 3 | -0.0236861 |
| NOP58 | NOP58 ribonucleoprotein | -0.023396 |
| RNF145 | ring finger protein 145 | -0.0233412 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0232261 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0232121 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0231503 |
