| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.283298 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.213801 |
| ENO1 | enolase 1, (alpha) | 0.169981 |
| COL6A3 | collagen, type VI, alpha 3 | 0.143384 |
| MT2A | metallothionein 2A | 0.133083 |
| COL6A2 | collagen, type VI, alpha 2 | 0.127292 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.11819 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.117692 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.115455 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.107458 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.106673 |
| CD44 | CD44 molecule (Indian blood group) | 0.100442 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0987696 |
| ASPH | aspartate beta-hydroxylase | 0.095873 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0808359 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0768477 |
| LDHA | lactate dehydrogenase A | 0.0744598 |
| COL5A1 | collagen, type V, alpha 1 | 0.0739657 |
| PKM | pyruvate kinase, muscle | 0.0722974 |
| DST | dystonin | 0.0678646 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0673082 |
| CALR | calreticulin | 0.0645149 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0641958 |
| SEPTIN9 | septin 9 | 0.06088 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0593797 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0590416 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0578496 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0569804 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0569112 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0545545 |
| RRM2 | ribonucleotide reductase M2 | 0.0537849 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.053707 |
| CANX | calnexin | 0.0535476 |
| FAM13A | family with sequence similarity 13, member A | 0.0512276 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0484404 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0477822 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0474244 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.047192 |
| RPS3 | ribosomal protein S3 | 0.0470603 |
| CAPRIN2 | caprin family member 2 | 0.0456162 |
| RPL12 | ribosomal protein L12 | 0.0453856 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0450045 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0442216 |
| PRELID2 | PRELI domain containing 2 | 0.0438008 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0413273 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0401076 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0400141 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0390814 |
| WWOX | WW domain containing oxidoreductase | 0.0385806 |
| SMAD3 | SMAD family member 3 | 0.0383158 |
| ADM | adrenomedullin | 0.0379359 |
| PLEC | plectin | 0.036016 |
| INTS6 | integrator complex subunit 6 | 0.0356964 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0352577 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0350458 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0349375 |
| TPM3 | tropomyosin 3 | 0.0349201 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0346058 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0345557 |
| RPS12 | ribosomal protein S12 | 0.0344432 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0343819 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0343107 |
| ACTN1 | actinin, alpha 1 | 0.0342836 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0340273 |
| APP | amyloid beta (A4) precursor protein | 0.0340173 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0337592 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0333928 |
| ANGPTL4 | angiopoietin-like 4 | 0.0333398 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0330623 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.032812 |
| IER3 | immediate early response 3 | 0.0322987 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0321559 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0321148 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0316901 |
| TNS1 | tensin 1 | 0.0316884 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0315144 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0312911 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0310373 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0309947 |
| RPL35A | ribosomal protein L35a | 0.0306476 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0303158 |
| TFRC | transferrin receptor | 0.0301906 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0300886 |
| RPL26 | ribosomal protein L26 | 0.0295987 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0288303 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0287172 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.028629 |
| ZNF638 | zinc finger protein 638 | 0.028481 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.028453 |
| JAG1 | jagged 1 | 0.0282284 |
| YBX1 | Y box binding protein 1 | 0.0280291 |
| RPLP1 | ribosomal protein, large, P1 | 0.0279965 |
| DSPP | dentin sialophosphoprotein | 0.0277824 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0277492 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0277472 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0276376 |
| MAP1B | microtubule-associated protein 1B | 0.0274992 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0272171 |
| RPL37A | ribosomal protein L37a | 0.0271732 |
| DTNA | dystrobrevin, alpha | 0.0269637 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.303229 |
| VIM | vimentin | -0.273876 |
| IGF2 | insulin-like growth factor 2 | -0.119346 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0924269 |
| FN1 | fibronectin 1 | -0.0897029 |
| CDH13 | cadherin 13 | -0.083763 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0744094 |
| CDCP1 | CUB domain containing protein 1 | -0.0736251 |
| TENM2 | teneurin transmembrane protein 2 | -0.0709119 |
| ACTG1 | actin gamma 1 | -0.0669812 |
| CLMP | CXADR-like membrane protein | -0.0655555 |
| HMGA2 | high mobility group AT-hook 2 | -0.0545116 |
| SBF2 | SET binding factor 2 | -0.0528931 |
| EGR1 | early growth response 1 | -0.0502995 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0492656 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0472277 |
| CCND1 | cyclin D1 | -0.0469109 |
| RTN4 | reticulon 4 | -0.0455709 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0430831 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0424375 |
| COL1A1 | collagen, type I, alpha 1 | -0.0424369 |
| TMEM165 | transmembrane protein 165 | -0.0416382 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0408986 |
| TUBB6 | tubulin, beta 6 class V | -0.040279 |
| GLIS3 | GLIS family zinc finger 3 | -0.0400899 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.039504 |
| OSMR | oncostatin M receptor | -0.037064 |
| SETD5 | SET domain containing 5 | -0.0342178 |
| NF1 | neurofibromin 1 | -0.0311018 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0304602 |
| TMSB10 | thymosin beta 10 | -0.029914 |
| WASF2 | WAS protein family, member 2 | -0.0285144 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.028031 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0278527 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0278141 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0276672 |
| AGRN | agrin | -0.0272446 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0271084 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0270105 |
| PCNX4 | pecanex 4 | -0.0259767 |
| RIN2 | Ras and Rab interactor 2 | -0.0247185 |
| CUX1 | cut-like homeobox 1 | -0.0246773 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0246483 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0245783 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0244549 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0244486 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0241112 |
| MYADM | myeloid-associated differentiation marker | -0.0235325 |
| S100A10 | S100 calcium binding protein A10 | -0.0230873 |
| SYMPK | symplekin | -0.0227193 |
| PRR11 | proline rich 11 | -0.022368 |
| HM13 | histocompatibility (minor) 13 | -0.0223058 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -0.0221525 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0220198 |
| CD109 | CD109 molecule | -0.0216897 |
| FMN1 | formin 1 | -0.0210082 |
| RAI14 | retinoic acid induced 14 | -0.020735 |
| DSTN | destrin (actin depolymerizing factor) | -0.0206839 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0204032 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0199725 |
| CFDP1 | craniofacial development protein 1 | -0.0198536 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0196026 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0195753 |
| MIS18BP1 | MIS18 binding protein 1 | -0.019564 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0195586 |
| ZNF609 | zinc finger protein 609 | -0.0194138 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0193648 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0192901 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0191113 |
| TAOK1 | TAO kinase 1 | -0.0187768 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0187406 |
| IL1B | interleukin 1, beta | -0.0187391 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0184452 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0182972 |
| VASP | vasodilator-stimulated phosphoprotein | -0.0182614 |
| RHOA | ras homolog family member A | -0.0180699 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.017921 |
| PHF20 | PHD finger protein 20 | -0.0175832 |
| USP34 | ubiquitin specific peptidase 34 | -0.0174082 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0173459 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0172807 |
| CENPE | centromere protein E, 312kDa | -0.0172397 |
| INHBA | inhibin, beta A | -0.0169298 |
| DNER | delta/notch-like EGF repeat containing | -0.0166706 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0165705 |
| PCNX1 | pecanex 1 | -0.0165449 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0165094 |
| METTL15 | methyltransferase like 15 | -0.0164999 |
| HMGA1 | high mobility group AT-hook 1 | -0.0163686 |
| TPM4 | tropomyosin 4 | -0.0163542 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0162528 |
| GLG1 | golgi glycoprotein 1 | -0.0162151 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0161492 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0161478 |
| FAM193A | family with sequence similarity 193, member A | -0.0161223 |
| RNF149 | ring finger protein 149 | -0.0160296 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0159806 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0159792 |
| HIP1 | huntingtin interacting protein 1 | -0.0157878 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0157497 |
