| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.334604 |
| FN1 | fibronectin 1 | 0.311796 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.216558 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.141152 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.113719 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.11312 |
| CALR | calreticulin | 0.112001 |
| ENO1 | enolase 1, (alpha) | 0.0992853 |
| ASPH | aspartate beta-hydroxylase | 0.0828989 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0727586 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0633843 |
| LDHA | lactate dehydrogenase A | 0.0622741 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0609292 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0584204 |
| CANX | calnexin | 0.0573512 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0563707 |
| RND3 | Rho family GTPase 3 | 0.0552795 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0529794 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0511059 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0492631 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0479079 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0463661 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0448242 |
| PKM | pyruvate kinase, muscle | 0.0443731 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0442205 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0435286 |
| APP | amyloid beta (A4) precursor protein | 0.0427147 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.042603 |
| VMP1 | vacuole membrane protein 1 | 0.041322 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0411551 |
| NAV2 | neuron navigator 2 | 0.0397522 |
| CD44 | CD44 molecule (Indian blood group) | 0.0392945 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0362791 |
| INHBA | inhibin, beta A | 0.0359553 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0349983 |
| PLEC | plectin | 0.0346889 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0342177 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.033135 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0326689 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0318074 |
| TMSB4X | thymosin beta 4, X-linked | 0.0309867 |
| SP100 | SP100 nuclear antigen | 0.0293791 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0287128 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.027897 |
| RIGI | RNA sensor RIG-I | 0.0277229 |
| TUBB | tubulin, beta class I | 0.0272212 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0262645 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0261519 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0253677 |
| SMAD3 | SMAD family member 3 | 0.0253003 |
| JAG1 | jagged 1 | 0.0252374 |
| HYOU1 | hypoxia up-regulated 1 | 0.0251926 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0249345 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0246361 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0243809 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0238918 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0234142 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0232965 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0232043 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0226063 |
| HDAC9 | histone deacetylase 9 | 0.0225558 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0221578 |
| CEP95 | centrosomal protein 95kDa | 0.022114 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0220882 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0219957 |
| CLTC | clathrin, heavy chain (Hc) | 0.0219509 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0213481 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0212892 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0211548 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0210184 |
| CTSB | cathepsin B | 0.0209814 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0207885 |
| KIAA1217 | KIAA1217 | 0.0207605 |
| MAP4 | microtubule-associated protein 4 | 0.0206987 |
| CENPF | centromere protein F, 350/400kDa | 0.020579 |
| AHNAK | AHNAK nucleoprotein | 0.0204923 |
| CD2AP | CD2-associated protein | 0.0201556 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0200545 |
| PRELID2 | PRELI domain containing 2 | 0.019452 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0193657 |
| SFTPA2 | surfactant protein A2 | 0.0192487 |
| H1-0 | H1.0 linker histone | 0.0190519 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.019032 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0190037 |
| FMNL2 | formin-like 2 | 0.0188023 |
| LOX | lysyl oxidase | 0.0187014 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0184719 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0184499 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0181705 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0181071 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0180585 |
| TPR | translocated promoter region, nuclear basket protein | 0.0180221 |
| ADAR | adenosine deaminase, RNA-specific | 0.0179992 |
| CD164 | CD164 molecule, sialomucin | 0.0179434 |
| ARRDC3 | arrestin domain containing 3 | 0.0178203 |
| RPN1 | ribophorin I | 0.0177624 |
| PGM3 | phosphoglucomutase 3 | 0.0177193 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0176994 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0176963 |
| CAPRIN2 | caprin family member 2 | 0.0176753 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.281468 |
| NDRG1 | N-myc downstream regulated 1 | -0.238539 |
| COL1A1 | collagen, type I, alpha 1 | -0.169348 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.11876 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.108894 |
| CADM1 | cell adhesion molecule 1 | -0.104976 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.100206 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0735461 |
| PDE10A | phosphodiesterase 10A | -0.0715843 |
| CDH13 | cadherin 13 | -0.0694374 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0650543 |
| COL5A1 | collagen, type V, alpha 1 | -0.0636616 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0620163 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0598268 |
| COL1A2 | collagen, type I, alpha 2 | -0.0591818 |
| VIM | vimentin | -0.0545753 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0526236 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0482424 |
| VEGFA | vascular endothelial growth factor A | -0.0478483 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0458322 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.041841 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.03924 |
| KIF13A | kinesin family member 13A | -0.0384176 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0364318 |
| TMEM165 | transmembrane protein 165 | -0.0359546 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0353532 |
| FBN1 | fibrillin 1 | -0.0335321 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0330894 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.031395 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0312 |
| QKI | QKI, KH domain containing, RNA binding | -0.0310195 |
| PRR16 | proline rich 16 | -0.0308219 |
| RPL28 | ribosomal protein L28 | -0.0293145 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0289736 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0287035 |
| CD109 | CD109 molecule | -0.0277162 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0277003 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0276038 |
| ACTG1 | actin gamma 1 | -0.0274262 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0269558 |
| ATP13A3 | ATPase type 13A3 | -0.0268761 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0265505 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0264777 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0263884 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0263472 |
| CALD1 | caldesmon 1 | -0.0259518 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.025908 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0257764 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0253261 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0244646 |
| RHEB | Ras homolog enriched in brain | -0.0236592 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0233819 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0231215 |
| CLMP | CXADR-like membrane protein | -0.0228802 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0226766 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0225255 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0222647 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0221211 |
| SBF2 | SET binding factor 2 | -0.0216874 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0216802 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0215478 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | -0.0213498 |
| STC1 | stanniocalcin 1 | -0.0212129 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0206243 |
| SETD5 | SET domain containing 5 | -0.0205409 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0204267 |
| CA12 | carbonic anhydrase XII | -0.0202849 |
| RPS25 | ribosomal protein S25 | -0.0198118 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0197782 |
| EFNA5 | ephrin-A5 | -0.0196072 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0195988 |
| TENM3 | teneurin transmembrane protein 3 | -0.0195456 |
| TMSB10 | thymosin beta 10 | -0.0193885 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0193801 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0193459 |
| TFG | TRK-fused gene | -0.0191935 |
| USP3 | ubiquitin specific peptidase 3 | -0.0190216 |
| PHF21A | PHD finger protein 21A | -0.0189576 |
| PTMA | prothymosin, alpha | -0.0187882 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0187748 |
| GNAS | GNAS complex locus | -0.0186402 |
| ATG7 | autophagy related 7 | -0.0184538 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0183344 |
| TRAM1 | translocation associated membrane protein 1 | -0.0181706 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0181422 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0179966 |
| SULF1 | sulfatase 1 | -0.0179048 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0178879 |
| ZNF292 | zinc finger protein 292 | -0.0178196 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0177986 |
| GOLGA4 | golgin A4 | -0.0177792 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0177161 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0177036 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0176759 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0176629 |
| RPL35A | ribosomal protein L35a | -0.0176471 |
| PGK1 | phosphoglycerate kinase 1 | -0.0175781 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0174211 |
| PTEN | phosphatase and tensin homolog | -0.0173775 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0171963 |
